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1. Full Text Left–right asymmetry in the level of active Nodal protein produced in the node is translated into left–right asymmetry in the lateral plate of mouse embryos
by Kawasumi, Aiko and Nakamura, Tetsuya and Iwai, Naomi and Yashiro, Kenta and Saijoh, Yukio and Belo, Jose Antonio and Shiratori, Hidetaka and Hamada, Hiroshi
Developmental biology, ISSN 0012-1606, 05/2011, Volume 353, Issue 2, pp. 321 - 330
Left–right (L–R) asymmetry in the mouse embryo is generated in the node and is dependent on cilia-driven fluid flow, but how the initial asymmetry is transmitted from the node to the lateral plate has remained unknown... 
Smad | Nodal signaling | Node | Left–right asymmetry | Left-right asymmetry | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Phosphorylation | Humans | Male | Smad3 Protein - metabolism | Mesoderm - cytology | Mice, Neurologic Mutants | Biological Transport, Active | Nodal Protein - genetics | Forkhead Transcription Factors - metabolism | Female | Forkhead Transcription Factors - deficiency | Mesoderm - embryology | Signal Transduction | Smad2 Protein - metabolism | Mice, Transgenic | Forkhead Transcription Factors - genetics | Body Patterning - physiology | Mice, Knockout | Pregnancy | Animals | Enhancer Elements, Genetic | Left-Right Determination Factors - genetics | Mesoderm - metabolism | Mice | Nodal Protein - physiology | Body Patterning - genetics | Embryonic development | Index Medicus | node
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2. Full Text The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry
by Long, S
Development (Cambridge), ISSN 1477-9129, 06/2003, Volume 130, Issue 11, pp. 2303 - 2316
We have identified and characterized a new zebrafish gene, southpaw , that is required for visceral and diencephalic left-right asymmetry... 
Zebrafish | Nodal-related | Asymmetry | Southpaw | Left-right | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Amino Acid Sequence | Oligodeoxyribonucleotides, Antisense - pharmacology | Heart Defects, Congenital - embryology | DNA, Complementary - genetics | Molecular Sequence Data | Oligodeoxyribonucleotides, Antisense - genetics | Mesoderm - cytology | Zebrafish - embryology | Pancreas - embryology | Organizers, Embryonic - embryology | Zebrafish - genetics | Sequence Homology, Amino Acid | Heart Defects, Congenital - genetics | Diencephalon - embryology | Animals | In Situ Hybridization | Transforming Growth Factor beta - genetics | Gene Expression Regulation, Developmental | Models, Biological | Base Sequence | Mutation | Zebrafish Proteins - genetics | Body Patterning - genetics | Nodal Protein | Index Medicus
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3. Full Text Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut
by Essner, J. J
Development (Cambridge), ISSN 1477-9129, 02/2005, Volume 132, Issue 6, pp. 1247 - 1260
Monocilia have been proposed to establish the left-right (LR) body axis in vertebrate embryos by creating a directional fluid flow that triggers asymmetric... 
Kupffer's vesicle | Left-right dynein | Left-right patterning | Dorsal forerunner cells | Cilia | Organogenesis | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cilia - physiology | Gastrointestinal Tract - embryology | Brain - embryology | Animals | Transforming Growth Factor beta - genetics | Left-Right Determination Factors | Zebrafish Proteins - metabolism | Heart - embryology | Zebrafish Proteins - genetics | Zebrafish - embryology | Transforming Growth Factor beta - metabolism | Body Patterning - physiology | Index Medicus
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4. Full Text Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target
by Gamse, J. T
Development (Cambridge), ISSN 1477-9129, 09/2005, Volume 132, Issue 21, pp. 4869 - 4881
.... Under the influence of Nodal signaling, positioning of the parapineal sets the direction of habenular asymmetry and thereby determines the left-right origin of habenular projections onto the midbrain... 
Leftover gene | Habenular nuclei | Left-right asymmetry | Fasciculus retroflexus | KCTD gene family | Diencephalon | Interpeduncular nucleus | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Epithalamus - physiology | Animals | Mesencephalon - embryology | Neurons | Body Patterning | Embryo, Nonmammalian | Epithalamus - embryology | Nervous System - embryology | Pineal Gland - embryology | Zebrafish - embryology | Habenula - embryology | Index Medicus | Mesencephalon | Nervous System | Pineal Gland | Biochemistry, Molecular Biology | Zebrafish | Epithalamus | Life Sciences | Habenula | Molecular biology
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5. Full Text Intrinsic chiral properties of the Xenopus egg cortex: an early indicator of left-right asymmetry?
by Michael V. Danilchik and Elizabeth E. Brown and Kristen Riegert
Development, ISSN 0950-1991, 11/2006, Volume 133, Issue 22, pp. 4517 - 4526
...) axis also emerges, presaging eventual morphological asymmetries of the heart and other viscera... 
Egg | Actin | Left-right asymmetry | Xenopus laevis | Cytoskeleton | Microtubule | Axis formation | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Diacetyl - analogs & derivatives | Ovum - cytology | Animals | Actins - metabolism | Histocytochemistry | Cell Polarity - physiology | Xenopus - embryology | Body Patterning - physiology | Index Medicus
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6. Full Text Nodal signalling is involved in left–right asymmetry in snails
by Grande, Cristina and Patel, Nipam H
Nature (London), ISSN 1476-4687, 12/2008, Volume 457, Issue 7232, pp. 1007 - 1011
Many animals display specific internal or external features with left-right asymmetry... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Paired Box Transcription Factors - genetics | Signal Transduction | Snails - genetics | Snails - drug effects | Snails - metabolism | Molecular Sequence Data | Nodal Protein - metabolism | Snails - embryology | Body Patterning - physiology | Animals | Nodal Protein - genetics | Gene Expression Regulation, Developmental | Body Patterning - genetics | Paired Box Transcription Factors - metabolism | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Snails | Genes | Studies | Cell division | Mollusks | Embryos | Cells | Index Medicus
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7. Full Text Cerberus–Nodal–Lefty–Pitx signaling cascade controls left–right asymmetry in amphioxus
by Guang Li and Xian Liu and Chaofan Xing and Huayang Zhang and Sebastian M. Shimeld and Yiquan Wang
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 4/2017, Volume 114, Issue 14, pp. 3684 - 3689
Many bilaterally symmetrical animals develop genetically programmed left–right asymmetries. In vertebrates, this process is under the control of Nodal signaling, which is restricted to the left side by antagonists Cerberus and Lefty... 
Embryonic development | Amphioxus | Nodal|left-right asymmetry | TALEN | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Heat shock proteins | Vertebrates | Genotype & phenotype | Gene expression | Index Medicus | amphioxus | left–right asymmetry | Biological Sciences | Nodal | embryonic development
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8. Left-right asymmetry in embryonic development and breast cancer: Common molecular determinants?
by Wilting, J and Hagedorn, M
Current medicinal chemistry, ISSN 0929-8673, 2011, Volume 18, Issue 36, pp. 5519 - 5527
.... In recent years, our knowledge about the molecular control of left-right asymmetry during embryonic development has grown considerably... 
Nodal | FGF | HB-EGF | Left-right asymmetry | HGF | Notch | Breast cancer | Laterality | Lefty | Pitx2 | FoxA2 | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Pregnancy | Animals | Breast Neoplasms - genetics | Humans | Left-Right Determination Factors - genetics | Embryonic Development - genetics | Left-Right Determination Factors - metabolism | Female | Male | Body Patterning - genetics | Breast Neoplasms - metabolism
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9. Full Text Regulation of left-right asymmetry by thresholds of Pitx2c activity
by Chengyu Liu and Wei Liu and Mei-Fang Lu and Nigel A. Brown and James F. Martin
Development, ISSN 0950-1991, 06/2001, Volume 128, Issue 11, pp. 2039 - 2048
Although much progress has been made in understanding the molecular mechanisms regulating left-right asymmetry, the final events of asymmetric organ morphogenesis remain poorly understood... 
Morphogenesis | Mouse | Left-right asymmetry | Homebox | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Duodenum - embryology | Gene Expression | Transcription Factors - physiology | Mice, Inbred C57BL | Transcription Factors - genetics | Homeodomain Proteins - genetics | Protein Isoforms - physiology | Nuclear Proteins | Animals | Alleles | Body Patterning | Mice | Homeodomain Proteins - physiology | Protein Isoforms - genetics | heterotaxia | Pitx2 gene | Index Medicus
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10. Full Text A unified model for left–right asymmetry? Comparison and synthesis of molecular models of embryonic laterality
by Vandenberg, Laura N and Levin, Michael
Developmental biology, ISSN 0012-1606, 07/2013, Volume 379, Issue 1, pp. 1 - 15
.... Yet, a large body of evidence suggests that biophysical, molecular, and bioelectrical asymmetries exist much earlier in development, some as early as the first cell cleavage after fertilization... 
Cytoskeleton | Asymmetry | Laterality | Chirality | Left–right | Cilia | Left-right | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Polarity | Chromatids - genetics | Cytoskeleton - genetics | Cytoplasm - metabolism | Penetrance | Embryonic Development | Cilia - metabolism | Cilia - genetics | Chromatids - metabolism | Animals | Gene Expression Regulation, Developmental | Models, Biological | Body Patterning | Cytoskeleton - metabolism | Models, Animal | Cytoplasm - genetics | Mice | Cell Movement | Models | Evolutionary biology | Developmental biology | Analysis | Index Medicus | asymmetry | cilia | chirality | cytoskeleton | left-right | laterality
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