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Circulation, ISSN 0009-7322, 11/2004, Volume 110, Issue 20, pp. 3259 - 3269
Background - Weight loss in obese insulin-resistant but not in insulin-sensitive persons reduces coronary heart disease risk. To what extent changes in gene... 
Obesity | Lipoproteins | Circadian rhythm | Genes | Atherosclerosis | atherosclerosis | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | LIPID-METABOLISM | genes | LOW-DENSITY-LIPOPROTEIN | BLOOD-PRESSURE VARIABILITY | BODY-COMPOSITION | circadian rhythm | PPAR-GAMMA | PERIPHERAL VASCULAR DISEASE | CIRCULATING OXIDIZED LDL | CORONARY-HEART-DISEASE | HEMATOLOGY | lipoproteins | obesity | TRANSGENIC MICE | ADIPOSE-TISSUE | Obesity - diet therapy | Up-Regulation | Oxidative Stress | Arteriosclerosis - genetics | Obesity - genetics | Adipose Tissue - metabolism | Myocardium - metabolism | Receptors, LDL - deficiency | Autoantibodies - analysis | Transcription, Genetic | Heart Function Tests | PPAR gamma - genetics | Arteriosclerosis - etiology | Receptors, LDL - genetics | Echocardiography | PPAR alpha - biosynthesis | Obesity - complications | Mice, Inbred C57BL | Adipose Tissue - pathology | Insulin Resistance | Lipoproteins, LDL - analysis | Aorta, Thoracic - metabolism | Gene Expression Regulation - physiology | Genotype | PPAR alpha - genetics | Inflammation | Leptin - genetics | Circadian Rhythm | PPAR gamma - biosynthesis | Mice, Knockout | Obesity - pathology | Hypertriglyceridemia - prevention & control | Arteriosclerosis - prevention & control | Animals | Weight Loss | Hypertriglyceridemia - etiology | Glucose - metabolism | Mice, Obese | Arteriosclerosis - metabolism | Mice | Leptin - deficiency | Lipoproteins, LDL - immunology | Index Medicus | Abridged Index Medicus
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 03/2016, Volume 43, Issue 5, pp. 653 - 661
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19888 - 19899
Farnesoid X receptor alpha (FXR alpha) as a bile acid sensor plays potent roles in multiple metabolic processes, and its antagonist has recently revealed... 
OBESITY | HOMEOSTASIS | NATURAL PRODUCT | CHOLESTEROL | METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | BILE-ACID RECEPTOR | LIGAND | IDENTIFICATION | ORPHAN NUCLEAR RECEPTOR | AGONIST | Glucose-6-Phosphatase - genetics | Receptors, Leptin - genetics | Humans | Phosphoenolpyruvate Carboxykinase (ATP) - antagonists & inhibitors | Crystallography, X-Ray | Male | Hepatocytes - metabolism | Hepatocytes - cytology | Protein Isoforms - metabolism | ATP-Binding Cassette Transporters - genetics | Protein Isoforms - agonists | Receptors, Cytoplasmic and Nuclear - chemistry | ATP-Binding Cassette Transporters - metabolism | Benzamides - pharmacology | Retinoid X Receptors - genetics | Retinoid X Receptors - metabolism | Hepatocytes - drug effects | Benzamides - chemistry | Recombinant Proteins - metabolism | Signal Transduction | Isoxazoles - antagonists & inhibitors | Gene Expression Regulation | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Recombinant Proteins - genetics | Glucose-6-Phosphatase - metabolism | Hep G2 Cells | Mice, Knockout | Isoxazoles - pharmacology | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Receptors, Leptin - deficiency | Animals | ATP Binding Cassette Subfamily B Member 11 | Retinoid X Receptors - agonists | Glucose-6-Phosphatase - antagonists & inhibitors | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Mice | Molecular Docking Simulation | Mutation | Primary Cell Culture | Protein Isoforms - antagonists & inhibitors | ATP-Binding Cassette Transporters - antagonists & inhibitors | Protein Isoforms - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Protein Structure and Folding | FXR | homodimerization | molecular pharmacology | crystal structure | nuclear receptor | transcription target gene | metabolic disease | antagonist
Journal Article
Circulation, ISSN 0009-7322, 04/2008, Volume 117, Issue 17, pp. 2253 - 2261
Background - In obesity, decreases in adiponectin and increases in proinflammatory adipokines are associated with heart disease. Because adipocytes express... 
Obesity | Adipose tissue | Mineralocorticoid receptor | Diabetes mellitus | Inflammation | Aldosterone | Aldosterone antagonists | MACROPHAGE INFILTRATION | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | aldosterone | adipose tissue | diabetes mellitus | mineralocorticoid receptor | inflammation | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | aldosterone antagonists | HEMATOLOGY | TYPE-2 DIABETES-MELLITUS | TRANSCRIPTIONAL REGULATION | obesity | ADIPOSE-TISSUE | Diabetes Mellitus, Experimental - drug therapy | Body Weight | Myocardium - immunology | Obesity - drug therapy | Obesity - immunology | Receptors, Mineralocorticoid - metabolism | Male | PPAR gamma - immunology | Adipose Tissue - immunology | RNA, Messenger - metabolism | Inflammation - complications | Inflammation - drug therapy | Mice, Mutant Strains | Adipokines - genetics | Adiponectin - genetics | Diabetes Mellitus, Experimental - complications | Leptin - immunology | Mineralocorticoid Receptor Antagonists | PPAR gamma - genetics | Obesity - complications | Homeostasis - immunology | Aldosterone - pharmacology | Adipokines - immunology | Inflammation - immunology | Leptin - genetics | 3T3-L1 Cells | Diabetes Mellitus, Experimental - immunology | Animals | Triglycerides - blood | Biomarkers | Mice | Adiponectin - immunology | Adipose Tissue - drug effects | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2015, Volume 125, Issue 7, pp. 2861 - 2876
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