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Neuroscience Research, ISSN 0168-0102, 07/2018, Volume 132, pp. 46 - 52
Aberrant cell cycle re-entry promotes neuronal death in various neurological diseases. Thus, cyclin-dependent kinases (CDKs) seem to be one of potential... 
Seizure | Flavopiridol | CDK5 | Epilepsy | Leptomycin B | Index Medicus
Journal Article
by Kim, JE and Kang, TC
NEUROSCIENCE RESEARCH, ISSN 0168-0102, 07/2018, Volume 132, pp. 46 - 52
Aberrant cell cycle re-entry promotes neuronal death in various neurological diseases. Thus, cyclin-dependent kinases (CDKs) seem to be one of potential... 
APOPTOSIS | Flavopiridol | CDK5 | PATHWAY | Epilepsy | Seizure | NEUROSCIENCES | Leptomycin B
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2019, Volume 62, Issue 5, pp. 2390 - 2403
Influenza A viruses (IAVs) have caused worldwide epidemics and pandemics by reassortment and generation of drug-resistant mutants, which render antivirals and... 
ANTIVIRAL AGENTS | NUCLEAR EXPORT | CHEMISTRY, MEDICINAL | INHIBITION | LEPTOMYCIN B | INFLUENZA-A VIRUS
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 04/2009, Volume 124, Issue 8, pp. 1829 - 1840
The Karyopherin proteins are involved in nucleo-cytoplasmic trafficking and are critical for protein anti RNA subcellular localization. Recent studies suggest... 
HUMAN-PAPILLOMAVIRUS TYPE-16 | Karyopherin alpha 2 | LEPTOMYCIN-B | NUCLEAR EXPORT | nuclear transport proteins | MINOR CAPSID PROTEIN | INTRAEPITHELIAL NEOPLASIA | cervical cancer | IMPORTIN-ALPHA | P53 | Crm1 | Karyopherin beta 1 | MESSENGER-RNA | ONCOLOGY | EXPRESSION | NUCLEOCYTOPLASMIC TRANSPORT
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 2, pp. 383 - 389
Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is a promising anti-tumour agent that induces apoptosis of malignant cells through activation... 
TRAIL | Osteosarcoma | Death receptor | Nuclear export inhibitor | Aldehyde dehydrogenase | Apoptosis | Leptomycin B | Viral antibodies | International trade | Relapse | Antibodies | Metastasis | Aldehydes | Exports | Diseases | Index Medicus
Journal Article
ANNALS OF SURGICAL ONCOLOGY, ISSN 1068-9265, 07/2011, Volume 18, Issue 7, pp. 2093 - 2103
Perturbations in the nuclear microenvironment, including transport systems, play a critical role in malignant progression, but the nuclear import abnormalities... 
BREAST-CANCER | SURGERY | IMPORT | CELLS | RISK-FACTORS | ONCOLOGY | INTRAHEPATIC RECURRENCE | RESECTION | PROTEIN EXPRESSION | GENE-EXPRESSION | LEPTOMYCIN-B | NUCLEAR MICROENVIRONMENTS
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2005, Volume 102, Issue 23, pp. 8150 - 8155
Signal transducer and activator of transcription (STAT)3 is a member of a family of DNA-binding factors that function to induce expression of responsive genes.... 
transcription factor | DNA-BINDING DOMAIN | LOCALIZATION SIGNAL | signal transduction | PORE COMPLEX | MULTIDISCIPLINARY SCIENCES | EXPORT SIGNALS | MESSENGER-RNA | nuclear translocation | INTERFERON REGULATORY FACTOR-3 | LEPTOMYCIN B | C-JUN | NUCLEOCYTOPLASMIC TRANSLOCATION
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5725 - 13
Microtubules of all eukaryotic cells are formed by alpha-and beta-tubulin heterodimers. In addition to the well known cytoplasmic tubulins, a subpopulation of... 
LOCALIZATION | PROTEIN | INHIBITION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | LEPTOMYCIN-B | SIGNALS | RECEPTOR | CRM1 | BETA(II)-TUBULIN | GAMMA-TUBULIN | Animal models | Tubulin | Interphase | Microtubules | Nuclear transport | Plant cells | Leptomycin B | Life Sciences | Molecular biology | Biochemistry, Molecular Biology
Journal Article
EXPERIMENTAL BIOLOGY AND MEDICINE, ISSN 1535-3702, 02/2016, Volume 241, Issue 3, pp. 273 - 281
Opioid growth factor receptor (OGFr) facilitates growth inhibition in the presence of its specific ligand opioid growth factor (OGF), chemically termed... 
OGFr | SIGNAL | SYSTEM | MEDICINE, RESEARCH & EXPERIMENTAL | LOCALIZATION | leptomycin B | PATHWAY | PROTEIN-SEQUENCE | CELL-PROLIFERATION | nuclear export signaling | CRM1 | AXIS
Journal Article
Journal Article
Leukemia, ISSN 0887-6924, 01/2013, Volume 27, Issue 1, pp. 66 - 74
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 03/2018, Volume 314, Issue 3, pp. C334 - C348
Foxo transcription factors promote protein breakdown and atrophy of skeletal muscle fibers. Foxo transcriptional effectiveness is largely determined by... 
IGF-I | Nuclear translocation | Skeletal muscle | Foxo1 | Cell culture | Transcription factors | Phosphorylation | Insulin-like growth factor I | AKT protein | Muscular system | Nuclei | Leptomycin B | Fibers | Studies | Atrophy | FOXO1 protein | Green fluorescent protein | Forkhead protein | Skeletal system | Index Medicus | skeletal muscle | nuclear translocation
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 11/2010, Volume 17, Issue 11, pp. 1367 - 1376
Journal Article