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1. Full Text Adjuvant letrozole and tamoxifen alone or sequentially for postmenopausal women with hormone receptor-positive breast cancer: Long-term follow-up of the BiG 1-98 trial
by Ruhstaller, Thomas and Giobbie-Hurder, Anita and Colleoni, Marco and Jensen, Maj-Britt and Ejlertsen, Bent and De Azambuja, Evandro and Neven, Patrick and Láng, István and Jakobsen, Erik Hugger and Gladieff, Laurence and Bonnefoi, Hervé and Harvey, Vernon J and Spazzapan, Simon and Tondini, Carlo and Del Mastro, Lucia and Veyret, Corinne and Simoncini, Edda and Gianni, Lorenzo and Rochlitz, Christoph and Kralidis, Elena and Zaman, Khalil and Jassem, Jacek and Piccart-Gebhart, Martine and Di Leo, Angelo and Gelber, Richard D and Coates, Alan S and Goldhirsch, Aron and Thürlimann, Beat and Regan, Meredith M and members of the BIG 1-98 Collaborative Group and the International Breast Cancer Study Group and for the members of the BIG 1-98 Collaborative Group and the International Breast Cancer Study Group
Journal of clinical oncology, ISSN 0732-183X, 01/2019, Volume 37, Issue 2, pp. 105 - 114
Letrozole - administration & dosage | Receptors, Estrogen - metabolism | Double-Blind Method | Drug Administration Schedule | Antineoplastic Agents, Hormonal - administration & dosage | Humans | Letrozole - therapeutic use | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Breast Neoplasms - drug therapy | Tamoxifen - administration & dosage | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Antineoplastic Agents, Hormonal - therapeutic use | Letrozole - adverse effects | Tamoxifen - therapeutic use | Postmenopause | Female | Aged | Chemotherapy, Adjuvant | Tamoxifen - adverse effects | Index Medicus | ORIGINAL REPORTS
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2. Full Text Quantitative comparative analysis uncovered the role of E2 in Nile tilapia GSD + TE
by Teng, Jian and Chen, Hong Ju and Xu, Gao Peng and Wang, Yao Yao and Zhao, Yan and Ji, Xiang Shan
Aquaculture, ISSN 0044-8486, 12/2020, Volume 529, p. 735656
Cyp19a1a | High temperature | Nile tilapia | Letrozole | Estrogen
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3. Full Text Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial
by Mamounas, Eleftherios P and Bandos, Hanna and Lembersky, Barry C and Jeong, Jong-Hyeon and Geyer, Charles E and Rastogi, Priya and Fehrenbacher, Louis and Graham, Mark L and Chia, Stephen K and Brufsky, Adam M and Walshe, Janice M and Soori, Gamini S and Dakhil, Shaker R and Seay, Thomas E and Wade, James L and McCarron, Edward C and Paik, Soonmyung and Swain, Sandra M and Wickerham, D Lawrence and Wolmark, Norman
The lancet oncology, ISSN 1470-2045, 01/2019, Volume 20, Issue 1, pp. 88 - 99
Life Sciences & Biomedicine | Oncology | Science & Technology | Aromatase Inhibitors - administration & dosage | Letrozole - administration & dosage | Multivariate Analysis | Receptors, Estrogen - metabolism | Double-Blind Method | Humans | Letrozole - therapeutic use | Middle Aged | Breast Neoplasms - drug therapy | Receptors, Progesterone - metabolism | Disease-Free Survival | Receptors, Progesterone - analysis | Aromatase Inhibitors - adverse effects | Breast Neoplasms - pathology | Letrozole - adverse effects | Tamoxifen - therapeutic use | Intention to Treat Analysis | Postmenopause | Female | Aged | Chemotherapy, Adjuvant | Aromatase Inhibitors - therapeutic use | Antimitotic agents | Usage | Care and treatment | Analysis | Clinical trials | Breast cancer | Postmenopausal women | Product development | Antineoplastic agents | Health aspects | Cancer | Index Medicus
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4. The NEOLETEXE trial: a neoadjuvant cross-over study exploring the lack of cross resistance between aromatase inhibitors
by Bahrami, Nazli and Sauer, Torill and Engebretsen, Siri and Aljabri, Belal and Bemanian, Vahid and Lindstrom, Jonas and Luders, Torben and Kristensen, Vessela and Lorentzen, Annika and Loeng, Marie and Odegard, Hilde Presterud and Kvaloy, Jan Oyvind and Vestol, Ingeborg Berge and Geisler, Stephanie Beate and Gravdehaug, Berit and Gundersen, Joanna Majak and Geisler, Jurgen
Future oncology (London, England), ISSN 1479-6694, 11/2019, Volume 15, Issue 32, pp. 3675 - 3682
Life Sciences & Biomedicine | Oncology | Science & Technology | Estradiol - blood | Breast Neoplasms - surgery | Receptors, Estrogen - metabolism | Aromatase Inhibitors - pharmacology | Humans | Letrozole - therapeutic use | Receptor, ErbB-2 - metabolism | Antineoplastic Agents - therapeutic use | Letrozole - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Postmenopause | Female | Neoadjuvant Therapy | Antineoplastic Agents - pharmacology | Aromatase Inhibitors - therapeutic use | Letrozole - administration & dosage | Drug Administration Schedule | Breast Neoplasms - drug therapy | Cross-Over Studies | Androstadienes - administration & dosage | Androstadienes - pharmacology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Androstadienes - therapeutic use | Drug Resistance, Neoplasm - drug effects
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5. Full Text Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy
by Warth, Benedikt and Raffeiner, Philipp and Granados, Ana and Huan, Tao and Fang, Mingliang and Forsberg, Erica M and Benton, H. Paul and Goetz, Laura and Johnson, Caroline H and Siuzdak, Gary
Cell chemical biology, ISSN 2451-9456, 03/2018, Volume 25, Issue 3, pp. 291 - 300.e3
drug-exposome interactions | untargeted metabolomics | bioactive food constituents | endocrine-disrupting chemicals | mTOR | metabolic pathway analysis | soy isoflavone | combinatory chemotherapy | Ibrance | CDK4/6 inhibitor | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Metabolomics | Receptors, Estrogen - metabolism | Pyridines - chemistry | Humans | Letrozole - therapeutic use | Phytoestrogens - chemistry | Piperazines - chemistry | Letrozole - pharmacology | MCF-7 Cells | Female | Principal Component Analysis | Phytoestrogens - pharmacology | Pyridines - therapeutic use | Carbon - metabolism | Zearalenone - chemistry | Genistein - chemistry | Piperazines - therapeutic use | Breast Neoplasms - drug therapy | Piperazines - pharmacology | Letrozole - chemistry | Diet | Metabolome - drug effects | Breast Neoplasms - pathology | Genistein - pharmacology | Pyridines - pharmacology | Zearalenone - pharmacology
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6. Full Text Chronic aromatase inhibition increases ventral hippocampal neurogenesis in middle-aged female mice
by Chaiton, Jessica A and Wong, Sarah J and Galea, Liisa AM
Psychoneuroendocrinology, ISSN 0306-4530, 08/2019, Volume 106, pp. 111 - 116
Middle-aged females | Estrogens | Doublecortin | Depression | Ki67 | Neurogenesis | Letrozole | Hippocampus | Endocrinology & Metabolism | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Cell Proliferation | Dentate Gyrus - metabolism | Aromatase Inhibitors - pharmacology | Microtubule-Associated Proteins - metabolism | Aromatase - metabolism | Neuropeptides - metabolism | Neural Stem Cells | Hippocampus - drug effects | Letrozole - pharmacology | Depression - drug therapy | Hippocampus - metabolism | Animals | Behavior, Animal - drug effects | Female | Mice | Neurogenesis - drug effects | Neurons - metabolism | Estrogens - metabolism | Letrozole - metabolism | Index Medicus
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7. Full Text Effect of misoprostol with and without letrozole on the induction of abortion for women with first‐trimester missed abortion
by Allameh, Zahra and Goharian, Maryam and Eslamian, Mohammad
International journal of gynecology and obstetrics, ISSN 0020-7292, 11/2020, Volume 151, Issue 2, pp. 214 - 218
Pregnancy | Misoprostol | Letrozole | Missed abortion | Medical abortion | Life Sciences & Biomedicine | Obstetrics & Gynecology | Science & Technology | Letrozole - administration & dosage | Double-Blind Method | Abortion, Missed - drug therapy | Humans | Letrozole - therapeutic use | Misoprostol - administration & dosage | Administration, Intravaginal | Treatment Outcome | Abortifacient Agents, Nonsteroidal - therapeutic use | Pregnancy Trimester, First | Young Adult | Iran | Abortifacient Agents, Nonsteroidal - administration & dosage | Adult | Female | Drug Therapy, Combination | Misoprostol - therapeutic use | Prenatal Care | Index Medicus
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8. Full Text Characterization of letrozole in human hair using LC-MS/MS and confirmation by LC-HRMS: Application to a doping case
by Ameline, Alice and Gheddar, Laurie and Raul, Jean-Sébastien and Kintz, Pascal
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, ISSN 1570-0232, 01/2021, Volume 1162, pp. 122495 - 122495
Hair | LC-MS/MS | LC-HRMS | Letrozole | Doping | Index Medicus
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9. Full Text Preexisting musculoskeletal burden and its development under letrozole treatment in early breast cancer patients
by Nabieva, Naiba and Häberle, Lothar and Brucker, Sara Y and Janni, Wolfgang and Volz, Bernhard and Loehberg, Christian R and Hartkopf, Andreas D and Walter, Christina‐Barbara and Baake, Gerold and Fridman, Alexander and Malter, Wolfram and Wuerstlein, Rachel and Harbeck, Nadia and Hoffmann, Oliver and Kuemmel, Sherko and Martin, Bernhard and Thomssen, Christoph and Graf, Heiko and Wolf, Christopher and Lux, Michael P and Bayer, Christian M and Rauh, Claudia and Hack, Carolin C and Almstedt, Katrin and Gass, Paul and Heindl, Felix and Brodkorb, Tobias and Lindner, Christoph and Kolberg, Hans‐Christian and Krabisch, Petra and Weigel, Michael and Steinfeld‐Birg, Dieter and Kohls, Andreas and Brucker, Cosima and Schulz, Volker and Fischer, Gunnar and Pelzer, Volker and Rack, Brigitte and Beckmann, Matthias W and Fehm, Tanja and Rody, Achim and Maass, Nicolai and Hein, Alexander and Fasching, Peter A
International journal of cancer, ISSN 0020-7136, 10/2019, Volume 145, Issue 8, pp. 2114 - 2121
letrozole | breast cancer | arthralgia/joint pain | myalgia/muscle and limb pain | endocrine treatment/therapy | aromatase inhibitor | Life Sciences & Biomedicine | Oncology | Science & Technology | Postmenopause - drug effects | Humans | Letrozole - therapeutic use | Middle Aged | Arthralgia - physiopathology | Arthralgia - chemically induced | Breast Neoplasms - drug therapy | Breast Neoplasms - physiopathology | Musculoskeletal Pain - chemically induced | Aromatase Inhibitors - adverse effects | Pain Measurement - methods | Time Factors | Letrozole - adverse effects | Female | Musculoskeletal Pain - physiopathology | Aged | Aromatase Inhibitors - therapeutic use | Postmenopause - physiology | Antimitotic agents | Cancer patients | Care and treatment | Breast cancer | Drug therapy | Antineoplastic agents | Cancer | Therapy | Pain | Statistical analysis | Aromatase | Joints (anatomy) | Muscles | Median (statistics) | Statistical tests | Index Medicus
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10. Full Text Relevant factors for the optimal duration of extended endocrine therapy in early breast cancer
by Blok, E.J and Kroep, Judith and Meershoek-Klein Kranenbarg, Elma and Duijm-de Carpentier, M and Putter, Hein and Liefers, Gerrit-Jan and Nortier, Johan W. R and Rutgers, Emiel and Seynaeve, Caroline and Velde, Cornelis
Breast cancer research and treatment, ISSN 0167-6806, 12/2017, pp. 1 - 8
Postmenopausal | Extended | IDEAL | Subgroup | Adjuvant | Letrozole
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11. Full Text Impact of palbociclib plus letrozole on patient-reported health-related quality of life: results from the PALOMA-2 trial
by Rugo, H S and Diéras, V and Gelmon, K A and Finn, R S and Slamon, D J and Martin, M and Neven, P and Shparyk, Y and Mori, A and Lu, D R and Bhattacharyya, H and Bartlett, C Huang and Iyer, S and Johnston, S and Ettl, J and Harbeck, N
Annals of oncology, ISSN 0923-7534, 04/2018, Volume 29, Issue 4, pp. 888 - 894
Health-related quality of life | Metastatic breast cancer | ER+/HER2 | Letrozole | Palbociclib | Life Sciences & Biomedicine | Oncology | Science & Technology | Piperazines - administration & dosage | Letrozole - administration & dosage | Pyridines - administration & dosage | Double-Blind Method | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Breast Neoplasms - drug therapy | Breast Neoplasms - physiopathology | Breast Neoplasms - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Placebos | Postmenopause | Quality of Life | Female | Index Medicus | letrozole | metastatic breast cancer | health-related quality of life | HER2 | Original | palbociclib | ER
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12. Full Text Letrozole concentration is associated with CYP2A6 variation but not with arthralgia in patients with breast cancer
by Borrie, Adrienne E and Rose, Rhiannon V and Choi, Yun-Hee and Perera, Francisco E and Read, Nancy and Sexton, Tracy and Lock, Michael and Vandenberg, Theodore A and Hahn, Karin and Dinniwell, Robert and Younus, Jawaid and Logan, Diane and Potvin, Kylea and Yaremko, Brian and Yu, Edward and Lenehan, John and Welch, Stephen and Tyndale, Rachel F and Teft, Wendy A and Kim, Richard B
Breast cancer research and treatment, ISSN 0167-6806, 11/2018, Volume 172, Issue 2, pp. 371 - 379
CYP2A6 | Breast cancer | Arthralgia | Letrozole | Pharmacogenomics | Life Sciences & Biomedicine | Oncology | Science & Technology | Aromatase Inhibitors - administration & dosage | Letrozole - administration & dosage | Cytochrome P-450 CYP2A6 - genetics | Antineoplastic Agents, Hormonal - administration & dosage | Humans | Middle Aged | Genotype | Arthralgia - physiopathology | Breast Neoplasms - drug therapy | Antineoplastic Agents, Hormonal - adverse effects | Aromatase Inhibitors - adverse effects | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Letrozole - blood | Aged, 80 and over | Breast Neoplasms - blood | Adult | Female | Aged | Arthralgia - genetics | Women | Care and treatment | Cancer patients | Adjuvant treatment | Cytochrome P-450 | Genetic aspects | Postmenopausal women | Health aspects | Cancer | Index Medicus
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13. Full Text Comparison of efficacy of letrozole and clomiphene citrate for induction of ovulation
by Jawad, Ariana and Ali, Mahabad and Jawad, Rojan
Zanco journal of medical sciences, ISSN 1995-5588, 07/2020, Volume 24, Issue 1, pp. 21 - 27
letrozole | clomiphene citrate | pregnancy | ovulation
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