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Cytokine & growth factor reviews, ISSN 1359-6101, 2015, Volume 26, Issue 5, pp. 533 - 544
Highlights • Leukemia inhibitory factor is a highly pleiotropic cytokine. • It belongs to the IL6 superfamily characterized by use of the receptor chain gp130... 
Advanced Basic Science | Pregnancy | Embryonic stem cells | Leukemia inhibitory factor | LIF receptor | Nerve and muscle | JAK/STAT/SOCS | IL-6 SIGNAL TRANSDUCER | FACTOR-RECEPTOR | ACTIVATED PROTEIN-KINASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | PRIMORDIAL GERM-CELLS | CELL BIOLOGY | ONCOSTATIN-M | EMBRYONIC STEM-CELLS | RAT SYMPATHETIC NEURONS | SKELETAL-MUSCLE REGENERATION | Cytokine Receptor gp130 - genetics | Humans | Mouse Embryonic Stem Cells - immunology | Embryo Implantation - genetics | Leukemia Inhibitory Factor - genetics | STAT Transcription Factors - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Blastocyst - immunology | MAP Kinase Signaling System - genetics | Human Embryonic Stem Cells - immunology | Janus Kinases - immunology | Receptors, OSM-LIF - immunology | Janus Kinases - genetics | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Cytokine Receptor gp130 - immunology | Leukemia Inhibitory Factor - immunology | Embryo Implantation - immunology | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | STAT Transcription Factors - genetics | Animals | Receptors, OSM-LIF - genetics | Mice | Leukemia | STAT | nerve and muscle | JAK | embryonic stem cells | pregnancy | SOCS | leukemia inhibitory factor
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 56, pp. 78 - 85
... to irreversible neurodegeneration, which currently is untreatable. There is much interest in potential therapeutics that promote remyelination and here we explore use of leukaemia inhibitory factor (LIF... 
Advanced Basic Science | Dentistry | Multiple sclerosis | Leukaemia inhibitory factor | Myelin | Nanotherapy | Remyelination | IMMUNE-MEDIATED DEMYELINATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MACROPHAGES | PROLIFERATION | MATURATION | ASTROCYTES | DELIVERY | MULTIPLE-SCLEROSIS | SECRETION | EXPRESSION | PLGA NANOPARTICLES | Gold - chemistry | Cytokines - metabolism | Nanoparticles - chemistry | Biocompatible Materials - chemistry | Mice, Inbred C57BL | Rats | Male | Axons - physiology | Chondroitin Sulfates - chemistry | Microscopy, Electron | Neural Stem Cells - cytology | Multiple Sclerosis - therapy | Proteoglycans - chemistry | Rats, Sprague-Dawley | Antigens - chemistry | Leukemia Inhibitory Factor - chemistry | Drug Delivery Systems | Animals | Cell Differentiation | Mice | Lysophosphatidylcholines - chemistry | Myelin Sheath - chemistry | Oligodendroglia - cytology | Nanoparticles | Analysis | Leukemia | Therapeutics | Sulfates | Biomedical engineering | Homeopathy | Materia medica and therapeutics | Surgical implants | Axons | Biomedical materials | Drug delivery systems | Process control | Mathematical models | Repair | OPC, oligodendrocyte precursor cell | NP, nanoparticle | PBS, phosphate buffered saline | OD, oligodendrocyte | MS, multiple sclerosis | EM, electron microscopy | CNS, central nervous system | LIF, leukaemia inhibitory factor | PFA, paraformaldehyde | dpl, days post lesion
Journal Article
Journal Article
Placenta (Eastbourne), ISSN 0143-4004, 2013, Volume 34, Issue 11, pp. 1014 - 1019
.... Leukemia inhibitory factor (LIF) has roles in extravillous trophoblast adhesion and invasion and is present in ectopic implantation sites... 
Internal Medicine | Obstetrics and Gynecology | Pregnancy | Implantation | EVT | Placenta | Ectopic | Leukemia inhibitory factor | EMBRYO IMPLANTATION | BLASTOCYST IMPLANTATION | FACTOR LIF | RECEPTOR | CYTOKINE | INTERLEUKIN-11 | DEVELOPMENTAL BIOLOGY | OBSTETRICS & GYNECOLOGY | REPRODUCTIVE BIOLOGY | UNEXPLAINED INFERTILITY | HUMAN FALLOPIAN-TUBE | HUMAN ENDOMETRIUM | EXPRESSION | Pregnancy, Tubal - metabolism | Embryo Implantation - drug effects | Coculture Techniques | Humans | Middle Aged | STAT3 Transcription Factor - agonists | Fallopian Tubes - surgery | Blastocyst - pathology | Leukemia Inhibitory Factor - genetics | Leukemia Inhibitory Factor - metabolism | Fallopian Tubes - pathology | Young Adult | Leukemia Inhibitory Factor Receptor alpha Subunit - metabolism | Adult | Female | Leukemia Inhibitory Factor - antagonists & inhibitors | Leukemia Inhibitory Factor Receptor alpha Subunit - antagonists & inhibitors | Spheroids, Cellular | Fallopian Tubes - drug effects | STAT3 Transcription Factor - metabolism | Polyethylene Glycols - pharmacology | Cell Line | Epithelium - drug effects | Epithelium - pathology | Pregnancy, Tubal - surgery | Epithelium - metabolism | Tissue Culture Techniques | Blastocyst - metabolism | Cell Adhesion - drug effects | Leukemia Inhibitory Factor - pharmacology | Blastocyst - drug effects | Pregnancy, Tubal - pathology | Leukemia Inhibitory Factor Receptor alpha Subunit - agonists | Leukemia Inhibitory Factor Receptor alpha Subunit - genetics | Placenta - drug effects | Placenta - metabolism | Fallopian Tubes - metabolism | Signal Transduction - drug effects | Adolescent | Placenta - pathology | Cell Proliferation - drug effects | STAT3 Transcription Factor - antagonists & inhibitors | Pregnancy, Ectopic | Pregnant women | Developmental biology | Mortality | Leukemia
Journal Article
International journal of molecular medicine, ISSN 1107-3756, 07/2018, Volume 42, Issue 1, pp. 131 - 140
Leukemia inhibitory factor (LIF) is the most pleiotropic cytokine of the interleukin-6 family, and is widely used to establish and maintain pluripotent stem cells, particularly mouse pluripotent stem cells... 
Marmoset | Phosphoinositide 3-kinase/AKT | T-box 3 | Induced pluripotent stem cells | Leukemia inhibitory factor | MEDICINE, RESEARCH & EXPERIMENTAL | phosphoinositide 3-kinase/AKT | SELF-RENEWAL | FACTOR LIF | RECEPTOR | induced pluripotent stem cells | marmoset | DIFFERENTIATION | leukemia inhibitory factor | CALLITHRIX-JACCHUS | EXPRESSION
Journal Article
PLoS pathogens, ISSN 1553-7366, 01/2017, Volume 13, Issue 1, p. e1006120
.... HTLV-1 bZIP factor (HBZ) is constitutively expressed in HTLV-1 infected cells and ATL cells and promotes T-cell proliferation... 
PROTEIN | PROGRAMMED DEATH-1 | TRANSCRIPTION | MICROBIOLOGY | TAX | VIROLOGY | SUPPORTS PROLIFERATION | PATHWAY | VIRUS TYPE-I | LEUKEMIA-CELLS | PD-1 | FACTOR HBZ | PARASITOLOGY | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Basic-Leucine Zipper Transcription Factors - metabolism | Humans | Lymphocyte Activation - immunology | Receptors, Immunologic - biosynthesis | Programmed Cell Death 1 Receptor - biosynthesis | ZAP-70 Protein-Tyrosine Kinase - metabolism | HTLV-I Infections - transmission | Jurkat Cells | Mice, Inbred C57BL | Cell Proliferation - physiology | Programmed Cell Death 1 Receptor - metabolism | Mice, Transgenic | Basic-Leucine Zipper Transcription Factors - genetics | CD3 Complex - metabolism | Encephalomyelitis, Autoimmune, Experimental - virology | HTLV-I Infections - virology | Retroviridae Proteins - genetics | Animals | Proteins - metabolism | Retroviridae Proteins - metabolism | Cell Line, Tumor | Human T-lymphotropic virus 1 - pathogenicity | T-Lymphocytes - immunology | Mice | GRB2 Adaptor Protein - metabolism | Receptors, Immunologic - metabolism | Cell death | Analysis | Physiological aspects | Development and progression | Research | Non-Hodgkin's lymphomas | T cells | Medical research | Flow cytometry | Research & development--R&D | Laboratories | Funding | Genes | Leukemia | T cell receptors | Inflammatory diseases | Cell growth | Immunology | Lymphocytes | Rodents | Physiology | Life sciences | Lymphomas | Localization | Research & development | R&D
Journal Article
PloS one, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e25288
.... Here, we investigated the role of leukemia inhibitory factor (LIF) in human and murine decidualization. Ex vivo human (H... 
IN-VITRO | EARLY-PREGNANCY | PROGESTERONE | LIF-RECEPTOR | EMBRYO IMPLANTATION | MULTIDISCIPLINARY SCIENCES | BLASTOCYST IMPLANTATION | INTERLEUKIN-11 | DIFFERENTIATION | MOUSE UTERUS | EXPRESSION | Immunohistochemistry | Decidua - cytology | Humans | Endometrium - drug effects | Leukemia Inhibitory Factor - genetics | Leukemia Inhibitory Factor - metabolism | Leukemia Inhibitory Factor Receptor alpha Subunit - metabolism | Polymerase Chain Reaction | Pregnancy Trimester, First - metabolism | Female | Leukemia Inhibitory Factor Receptor alpha Subunit - antagonists & inhibitors | Endometrium - cytology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Endometrium - metabolism | Embryo Implantation - physiology | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Leukemia Inhibitory Factor - pharmacology | Blotting, Western | Decidua - metabolism | Leukemia Inhibitory Factor Receptor alpha Subunit - genetics | Pregnancy | Animals | Pregnancy Trimester, First - genetics | Desmin - metabolism | Desmin - genetics | Mice | Decidua - drug effects | In Vitro Techniques | Leukemia | Surgical implants | Phosphorylation | Laboratories | Estrogens | mRNA | Gestation | Western blotting | Interleukin 6 | Proteins | Ethics | Granulocyte colony-stimulating factor | Prolactin | Polyethylene glycol | Rodents | Interleukin 1 | Endometrium | Interleukin 8 | Menstruation | Cytokines | Developmental biology | Leukemia inhibitory factor | Stat3 protein | Implantation | Decidua | Interleukin 15 | Desmin | Medroxyprogesterone acetate | Biopsy | Womens health | Stromal cells | Ligands | In vivo methods and tests | Females | Acetic acid | Peritoneum
Journal Article
Journal Article