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Molecular biology and evolution, ISSN 0737-4038, 09/2019, Volume 36, Issue 9, pp. 2053 - 2068
Recent studies have drawn attention to the evolution of protein dynamics, in addition to sequence and structure, based on the premise... 
elastic network model | protein dynamics | TIM barrel | evolution | superfamily | LeuT | CATH | Methods | ProDy | PBP
Journal Article
Neuropharmacology, ISSN 0028-3908, 02/2019
The serotonin transporter (SERT) belongs to the monoamine transporter family, which also includes the dopamine and norepinephrine transporters. SERT is... 
Journal Article
eLife, ISSN 2050-084X, 02/2019, Volume 8
Nramp family transporters-expressed in organisms from bacteria to humans-enable uptake of essential divalent transition metals via an alternating-access... 
NEUROTRANSMITTER | MECHANISM | CRYSTAL-STRUCTURE | BACTERIAL HOMOLOG | SEQUENCE | BIOLOGY | ALTERNATING ACCESS | NA+ | LEUT | MOLECULAR-BASIS | FAMILY | Physiological aspects | Carrier proteins | Structure | Metal ions | Proteins | Transition metals | Mutation | Nramp protein | Metals | Cytoplasm
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 27314
HIV-1 Tat plays an important role in HIV-associated neurocognitive disorders (HAND) by disrupting neurotransmission including dopamine uptake by human dopamine... 
NEUROTRANSMITTER | TYROSINE 470 | PROTEIN | MULTIDISCIPLINARY SCIENCES | DYNAMICS | PARTICLE-MESH EWALD | LEUT | INDUCED INHIBITION | BINDING | EXPRESSION | BRAIN
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 8, pp. E1709 - E1808
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 02/2019, Volume 54, pp. 161 - 170
Neurotransmitter sodium symporters (NSS) belong to the SLC6 family of solute carriers and play an essential role in neurotransmitter homeostasis throughout the... 
STRUCTURAL BASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-SITE | SEROTONIN | X-RAY STRUCTURES | N-TERMINUS | LEUT | IDENTIFICATION | DOPAMINE TRANSPORTER | MEMBRANE-TRANSPORT | DIVERSE ANTIDEPRESSANTS | CELL BIOLOGY | Pharmacology | Wildlife conservation | Analysis | Membrane proteins
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 2009, Volume 19, Issue 4, pp. 425 - 432
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2018, Volume 114, Issue 1, pp. 10 - 14
Journal Article
Biochemistry, ISSN 0006-2960, 11/2016, Volume 55, Issue 46, pp. 6445 - 6455
NCKX1–5 are proteins involved in K+-dependent Na+/Ca2+ exchange in various signal tissues. Here we present a homology model of NCKX2 based on the crystal... 
SODIUM/CALCIUM EXCHANGER | SKIN PIGMENTATION | ADDITIVE FORCE-FIELD | HYPOMATURATION AMELOGENESIS IMPERFECTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSPORTER LEUT | PARTICLE MESH EWALD | NA/CA-K EXCHANGER | MOLECULAR-DYNAMICS SIMULATIONS | SYNDROMIC OCULOCUTANEOUS ALBINISM | GUI MEMBRANE-BUILDER
Journal Article