X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (24396) 24396
Publication (3055) 3055
Book Review (2985) 2985
Book Chapter (493) 493
Conference Proceeding (159) 159
Dissertation (112) 112
Book / eBook (70) 70
Newsletter (64) 64
Reference (31) 31
Web Resource (25) 25
Government Document (11) 11
Magazine Article (10) 10
Data Set (3) 3
Journal / eJournal (3) 3
Newspaper Article (3) 3
Trade Publication Article (3) 3
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (17424) 17424
ligand-binding (12692) 12692
biochemistry & molecular biology (9944) 9944
humans (8473) 8473
animals (7830) 7830
ligands (5696) 5696
ligand binding (5422) 5422
protein binding (4743) 4743
binding sites (4479) 4479
models, molecular (4234) 4234
research (3634) 3634
proteins (3622) 3622
amino acid sequence (3402) 3402
molecular sequence data (3342) 3342
analysis (3262) 3262
protein conformation (2977) 2977
crystal-structure (2885) 2885
biophysics (2615) 2615
kinetics (2590) 2590
ligand-binding domain (2590) 2590
cell biology (2233) 2233
protein structure, tertiary (1996) 1996
pharmacology & pharmacy (1970) 1970
mice (1897) 1897
article (1850) 1850
thermodynamics (1841) 1841
protein (1699) 1699
chemistry, multidisciplinary (1621) 1621
expression (1617) 1617
structure-activity relationship (1529) 1529
mutation (1519) 1519
chemical properties (1502) 1502
physiological aspects (1491) 1491
activation (1478) 1478
signal transduction (1415) 1415
crystallography, x-ray (1382) 1382
rats (1375) 1375
binding (1374) 1374
identification (1371) 1371
chemistry, medicinal (1335) 1335
multidisciplinary sciences (1296) 1296
escherichia-coli (1268) 1268
cell line (1255) 1255
receptors (1236) 1236
structure (1191) 1191
male (1167) 1167
chemistry, physical (1138) 1138
female (1067) 1067
protein structure, secondary (1067) 1067
biochemistry (1063) 1063
biochemical research methods (1040) 1040
base sequence (1005) 1005
endocrinology & metabolism (1003) 1003
molecular structure (995) 995
mutagenesis, site-directed (992) 992
drug design (941) 941
computer simulation (921) 921
cells (899) 899
receptor (897) 897
molecular dynamics simulation (878) 878
recombinant proteins - metabolism (844) 844
usage (836) 836
sequence homology, amino acid (835) 835
molecular dynamics (832) 832
proteins - chemistry (828) 828
fluorescence (827) 827
chemistry (818) 818
transfection (817) 817
affinity (811) 811
dimerization (808) 808
neurosciences (784) 784
structural basis (783) 783
mechanism (778) 778
gene expression (767) 767
enzymes (751) 751
recognition (738) 738
spectroscopy (737) 737
drug discovery (721) 721
recombinant proteins - chemistry (712) 712
biology (700) 700
complex (698) 698
molecular-dynamics (690) 690
protein folding (687) 687
hydrogen bonding (668) 668
site-directed mutagenesis (666) 666
crystal structure (658) 658
models, chemical (656) 656
sequence alignment (650) 650
myoglobin (647) 647
dynamics (644) 644
binding, competitive (634) 634
phosphorylation (625) 625
chemistry, analytical (623) 623
peptides (619) 619
amino acids (615) 615
cloning, molecular (611) 611
molecular biology (605) 605
domain (604) 604
mutagenesis (597) 597
protein-coupled receptors (586) 586
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (41) 41
Online Resources - Online (27) 27
Collection Dvlpm't (Acquisitions) - Closed Orders (7) 7
Collection Dvlpm't (Acquisitions) - Vendor file (7) 7
UofT at Mississauga - Stacks (7) 7
Chemistry (A D Allen) - Stacks (6) 6
UofT at Scarborough - Stacks (3) 3
Gerstein Science - Reference (2) 2
UTL at Downsview - May be requested (2) 2
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - Periodical Stacks (1) 1
Robarts - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (24504) 24504
Chinese (250) 250
Japanese (230) 230
French (32) 32
Russian (21) 21
German (14) 14
Spanish (10) 10
Czech (3) 3
Korean (2) 2
Portuguese (2) 2
Arabic (1) 1
Estonian (1) 1
Malay (1) 1
Swedish (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


2017, First edition., ISBN 9781119238485
Web Resource
07/2011
Background : Cell adhesion plays a pivotal role in diverse biological processes that occur in oncogenesis. BRCA1 was the first breast cancer susceptibility... 
BRCA1 | ligand binding
Web Resource
01/2018, ISBN 9781119238485, 312
eBook
07/2008
Background and Aims: Mycobacterium leprae is an obligate intracellular pathogen. Ligand-binding is an important factor in the success of chemoprevention and... 
Ligand binding | ErbB2 | Leprosy | Trastuzumab
Web Resource
NATURE, ISSN 0028-0836, 04/2016, Volume 532, Issue 7600, pp. 527 - 527
The human sigma 1 receptor is an enigmatic endoplasmic-reticulumresident transmembrane protein implicated in a variety of disorders including depression, drug... 
ACTIVATION | LIGAND-BINDING | CONSERVATION | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | MUTATION | AMINO-ACID-RESIDUES | TUMOR-CELLS | AMYOTROPHIC-LATERAL-SCLEROSIS | MEMBRANE-PROTEINS | EXPRESSION
Journal Article
NATURE, ISSN 0028-0836, 10/2013, Volume 502, Issue 7472, pp. 575 - 575
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which... 
ADRENOCEPTOR | COMPLEX | DISPLAY | LIGAND-BINDING | SERINE | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | RHODOPSIN | STATE | ADRENERGIC-RECEPTOR | AGONIST
Journal Article
SCIENCE, ISSN 0036-8075, 11/2007, Volume 318, Issue 5854, pp. 1258 - 1265
Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors constitute the largest family of eukaryotic signal transduction proteins that... 
MOLECULAR-MECHANISM | CRYSTALLIZATION | ACTIVATION | HUMAN GENOME | LIGAND-BINDING | BETA-ADRENERGIC-RECEPTOR | MEMBRANE | MULTIDISCIPLINARY SCIENCES | RHODOPSIN | HUMAN BETA-2-ADRENERGIC RECEPTOR | AGONIST
Journal Article
NATURE, ISSN 0028-0836, 08/2014, Volume 512, Issue 7514, pp. 270 - 270
Type-A gamma-aminobutyric acid receptors (GABA(A)Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in... 
GLYCINE RECEPTORS | MULTIDISCIPLINARY SCIENCES | X-RAY-STRUCTURE | EXTRACELLULAR DOMAIN | GATED ION CHANNELS | SIZE-EXCLUSION CHROMATOGRAPHY | LIGAND-BINDING DOMAIN | NICOTINIC ACETYLCHOLINE-RECEPTORS | MEMBRANE-PROTEINS | ALPHA-BUNGAROTOXIN | MAMMALIAN-CELLS
Journal Article
NATURE, ISSN 0028-0836, 11/2007, Volume 450, Issue 7168, pp. 383 - U4
Structural analysis of G-protein-coupled receptors (GPCRs) for hormones and neurotransmitters has been hindered by their low natural abundance, inherent... 
CRYSTALLIZATION | AGONIST ACTIVATION | DOMAIN | CONFORMATIONAL-CHANGES | LIGAND-BINDING | BOVINE RHODOPSIN | MULTIDISCIPLINARY SCIENCES | INTERMEDIATE | CRYSTALLOGRAPHY | BACTERIORHODOPSIN | BETA-ADRENERGIC RECEPTOR
Journal Article
Journal of Chemical Theory and Computation, ISSN 1549-9618, 09/2012, Volume 8, Issue 9, pp. 3314 - 3321
MM-PBSA is a post-processing end-state method to calculate free energies of molecules in solution. MMPBSA.py is a program written in Python for streamlining... 
GENERALIZED BORN MODEL | LIGAND-BINDING | CONTINUUM SOLVENT | DOCKING | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | SYSTEMS | PROTEIN-BINDING | PARAMETERS | INHIBITORS | BINDING FREE-ENERGIES | MOLECULAR-MECHANICS
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2001, Volume 123, Issue 22, pp. 5277 - 5284
A new approach of probing proximity effects in porphyrin-fullerene dyads by using an axial ligand coordination controlled "tail-on" and "tail-off" binding... 
Ligand binding (Biochemistry) | Research
Journal Article
Journal of Luminescence, ISSN 0022-2313, 08/2015, Volume 164, pp. 123 - 130
Interaction of pharmacologically important anticancer drug cytosine β-D arabinofuranoside with human serum albumin (HSA) at physiological pH 7.4 has been... 
Binding | Serum albumin | Molecular docking | Fluorescence quenching | SODIUM | LIGAND-BINDING | STRUCTURAL BASIS | DRUGS | CYTARABINE | OPTICS | CIPROFLOXACIN
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2013, Volume 135, Issue 50, pp. 18726 - 18729
Unprecedented direct acceptorless dehydrogenation of C-C single bonds adjacent to functional groups to form α,β-unsaturated compounds has been accomplished by... 
Chemical bonds | Ligand binding (Biochemistry) | Research | Properties | Dehydrogenation
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 07/2019, Volume 141, Issue 28, pp. 10948 - 10952
Chemically induced dimerization (CID) systems, in which two proteins dimerize only in the presence of a small molecule ligand, offer versatile tools for small... 
ANTIBODIES | HIGH-AFFINITY | ACTIVATION | LIGAND-BINDING PROTEINS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 07/2019
Ligand binding site structure has profound consequences for the evolution of function of protein complexes, particularly in homomers - complexes comprised of... 
Journal Article
SCIENCE, ISSN 0036-8075, 03/2012, Volume 335, Issue 6072, pp. 1106 - 1110
Extracellular ligand binding to G protein-coupled receptors (GPCRs) modulates G protein and beta-arrestin signaling by changing the conformational states of... 
PARTIAL AGONISTS | BETA-2-ADRENERGIC RECEPTOR | BETA ADRENERGIC-RECEPTOR | CONFORMATIONAL-CHANGES | LIGAND-BINDING | PROTEIN-COUPLED RECEPTOR | TRANSMEMBRANE RECEPTORS | CRYSTAL-STRUCTURE | NMR-SPECTROSCOPY | MULTIDISCIPLINARY SCIENCES | A(2A) ADENOSINE RECEPTOR
Journal Article
Molecular pharmacology, ISSN 0026-895X, 06/2019, Volume 95, Issue 6, pp. 606 - 614
Nicotinic acetylcholine receptors (nAChRs) are members of the Cys-loop superfamily of ligand-gated ion channels. Typically, channel activation follows the... 
PHARMACOLOGY & PHARMACY | ACTIVATION | PROTEIN | NACHR | LIGAND-BINDING DOMAIN | DETERMINANTS
Journal Article
NATURE, ISSN 0028-0836, 07/2010, Volume 466, Issue 7305, pp. 451 - U1
Obesity induced in mice by high-fat feeding activates the protein kinase Cdk5 (cyclin-dependent kinase 5) in adipose tissues. This results in phosphorylation... 
OLIGONUCLEOTIDE ARRAYS | LIGAND-BINDING | HORMONE | STIMULATION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | ACTIVATED-RECEPTOR-GAMMA | ADIPOGENESIS | EXPRESSION | THIAZOLIDINEDIONES | ADIPOSE-TISSUE | Drugs | Obesity | Phosphorylation | Receptors | Mice | Inhibition | Gene expression | Kinases
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.