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Scientific Reports, ISSN 2045-2322, 12/2020, Volume 10, Issue 1, pp. 1 - 12
Neurodevelopmental disorders (NDDs) are clinically and genetically extremely heterogeneous with shared phenotypes often associated with genes from the same... 
Phenotypes | Microencephaly | Insects | Morphology | Epilepsy | Lethality | Genetic engineering | Neurodevelopmental disorders | Mental retardation | Ubiquitin-protein ligase | Genetic screening
Journal Article
Scientific reports, ISSN 2045-2322, 01/2020, Volume 10, Issue 1, pp. 444 - 13
Hepatic stellate cells (HSCs) are essential for liver fibrosis. E6 associated protein (E6AP) is one of the E3-ubiquitin-protein ligase and has been studied in... 
Ubiquitin | Stellate cells | Phosphorylation | Smad protein | Carbon tetrachloride | Liver | MAP kinase | Kinases | Proteins | Signal transduction | Hepatocytes | Protein kinase | MicroRNAs | Plasminogen activator inhibitors | Fibrosis | miRNA | Ubiquitin-protein ligase | Cellular stress response | mRNA stability
Journal Article
Nature communications, ISSN 2041-1723, 01/2020, Volume 11, Issue 1, pp. 359 - 11
Protein ubiquitylation is involved in a plethora of cellular processes. While antibodies directed at ubiquitin remnants (K-ɛ-GG) have improved the ability to... 
Multiplexing | Ubiquitin | Spectroscopy | Profiling | Ionic mobility | Antibodies | Waveforms | Ions | Mass spectroscopy | Breast cancer | Tissues | Depth profiling | Substrates | Proteins | Proteomics | Measurement methods | Scientific imaging | Mass spectrometry | Ubiquitin-protein ligase
Journal Article
Neuron, ISSN 0896-6273, 02/2020, Volume 105, Issue 3, pp. 475 - 490.e6
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders with symptoms including social deficits, anxiety, and communication difficulties.... 
Translation | Mental disorders | Genomics | Genes | Excitability | Schizophrenia | Neurodevelopmental disorders | Risk factors | Cullin | Proteins | Signal transduction | Autism | Social behavior | Social interaction | Anxieties | Rodents | Cell cycle | Anxiety | Behavior | Glutamatergic transmission | Mutation | Neurotransmission | Ubiquitin-protein ligase
Journal Article
Neuron, ISSN 0896-6273, 02/2020, Volume 105, Issue 3, pp. 398 - 399
In this issue of Neuron, Dong et al. (2020) finds that deficiency of the psychiatric risk gene Cul3, which encodes an E3 ubiquitin ligase, leads to an... 
Ubiquitin | Translation | Mental disorders | Neurons | Genes | Excitability | Protein biosynthesis | Proteins | Autism | Anxieties | Morphology | Physiology | Anxiety | Behavior | Glutamatergic transmission | Mutation | Ubiquitin-protein ligase
Journal Article
Cancer Science, ISSN 1347-9032, 02/2020, Volume 111, Issue 2, pp. 489 - 501
Journal Article
Epilepsy Currents, ISSN 1535-7597, 1/2020, Volume 20, Issue 1, pp. 14 - 15
Clinical utility of multigene panel testing in adults with epilepsy and intellectual disability Borlot F, De Almeida BI, Combe SL, Andrade DM, Filloux FM,... 
Journal Article
SCIENCE, ISSN 0036-8075, 12/2019, Volume 366, Issue 6472, pp. 1486 - 1486
Journal Article
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 12/2019, Volume 132, p. 104585
Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by maternal mutation and paternal imprinting of the gene encoding UBE3A, an E3 ubiquitin... 
SILAM | Proteome | Angelman syndrome | UBE3A | autophagy | HAP1 | LOCALIZES | COMPLEX | UBIQUITIN LIGASE | PHOSPHORYLATION | SYNAPSE | MEDIATED DEGRADATION | ATG14 | NEUROSCIENCES | MUTATION | RUBICON | HUNTINGTIN-ASSOCIATED PROTEIN
Journal Article
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