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1. Full Text Ex Vivo Microscopy A Promising Next-Generation Digital Microscopy Tool for Surgical Pathology Practice
by Krishnamurthy, S and Brown, JQ and Iftimia, N and Levenson, RM and Rajadhyaksha, M
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, ISSN 0003-9985, 09/2019, Volume 143, Issue 9, pp. 1058 - 1068
Context.-The rapid evolution of optical imaging modalities in recent years has opened the opportunity for ex vivo tissue imaging, which has significant... 
MEDICINE, RESEARCH & EXPERIMENTAL | OPTICAL COHERENCE TOMOGRAPHY | LIGHT-SHEET MICROSCOPY | PATHOLOGY | ULTRAVIOLET SURFACE EXCITATION | MOHS MICROGRAPHIC SURGERY | CANCER MARGINS | HIGH-RESOLUTION | IN-VIVO | MULTIPHOTON MICROSCOPY | MEDICAL LABORATORY TECHNOLOGY | FLUORESCENCE CONFOCAL MICROSCOPY | REAL-TIME | Acridine | Decision making | Confocal microscopy | Histology | Breast cancer | Electronic medical records | Acridine orange | Pathology | Contrast agents | Microscopy | Lasers | Spectrum analysis | Light | Surgeons | Titanium | Artificial intelligence | Contrast media | Reflectance | Sulforhodamine | Tumors
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2. Full Text In vivo imaging of neural activity
by Yang, Weijian and Yuste, Rafael
Nature Methods, ISSN 1548-7091, 2017, Volume 14, Issue 4, pp. 349 - 359
Since the introduction of calcium imaging to monitor neuronal activity with single-cell resolution, optical imaging methods have revolutionized neuroscience by... 
DENDRITIC SPINES | NEURONAL-ACTIVITY | FLUORESCENCE MICROSCOPY | ACOUSTOOPTIC LENS | LIGHT-SHEET MICROSCOPY | MULTIFOCAL MULTIPHOTON MICROSCOPY | ADAPTIVE OPTICS | BIOCHEMICAL RESEARCH METHODS | FIELD-OF-VIEW | 2-PHOTON MICROSCOPY | HIGH-SPEED | Microscopy - methods | Animals | Microscopy, Fluorescence - methods | Calcium - metabolism | Microscopy - instrumentation | Humans | Neurons - physiology | Molecular Imaging - methods | Calcium - analysis | Brain - physiology | Equipment Design | Calcium imaging | Nervous system | In vivo methods and tests | Calcium | Microscopy | Imaging
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3. Full Text Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution
by Chen, Bi-Chang and Legant, Wesley R and Wang, Kai and Shao, Lin and Milkie, Daniel E and Davidson, Michael W and Janetopoulos, Chris and Wu, Xufeng S and Hammer, John A and Liu, Zhe and English, Brian P and Mimori-Kiyosue, Yuko and Romero, Daniel P and Ritter, Alex T and Lippincott-Schwartz, Jennifer and Fritz-Laylin, Lillian and Mullins, R. Dyche and Mitchell, Diana M and Bembenek, Joshua N and Reymann, Anne-Cecile and Böhme, Ralph and Grill, Stephan W and Wang, Jennifer T and Seydoux, Geraldine and Tulu, U. Serdar and Kiehart, Daniel P and Betzig, Eric
Science, ISSN 0036-8075, 10/2014, Volume 346, Issue 6208, pp. 1257998 - 439
Although fluorescence microscopy provides a crucial window into the physiology of living specimens, many biological processes are too fragile, are too small,... 
Microscopy - methods | Drosophila melanogaster - embryology | Animals | Embryo, Nonmammalian - ultrastructure | Imaging, Three-Dimensional - methods | Cell Communication | Molecular Imaging - methods | Mice | Spheroids, Cellular - ultrastructure | Caenorhabditis elegans - embryology | Embryonic Stem Cells - ultrastructure | MULTIDISCIPLINARY SCIENCES | Cell division | Lattice theory | Kinetics | Microscopy | Cellular biology | Optical lattices | Immunology | Light sheets | Dynamics | Imaging | Dynamical systems | Embryos | Biological activity
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4. Full Text Light sheet microscopy
by Weber, Michael and Mickoleit, Michaela and Huisken, Jan
2014, ISBN 9780124201385, Volume 123
This chapter introduces the concept of light sheet microscopy along with practical advice on how to design and build such an instrument. Selective plane... 
Mounting | Light sheet microscopy | Image processing | Developmental biology | Zebrafish | Ultramicroscopy | Fluorescence microscopy | Three-dimensional imaging | Selective plane illumination microscopy | Animals | Microscopy, Fluorescence - methods | Image Enhancement | Humans | Imaging, Three-Dimensional - methods | Time-Lapse Imaging - methods | Microscopy, Confocal - methods
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5. Full Text Swept confocally-aligned planar excitation (SCAPE) microscopy for high-speed volumetric imaging of behaving organisms
by Bouchard, Matthew B and Voleti, Venkatakaushik and Mendes, César S and Lacefield, Clay and Grueber, Wesley B and Mann, Richard S and Bruno, Randy M and Hillman, Elizabeth M. C
Nature Photonics, ISSN 1749-4885, 02/2015, Volume 9, Issue 2, pp. 113 - 119
We report a three-dimensional microscopy technique-swept, confocally-aligned planar excitation (SCAPE) microscopy-that allows volumetric imaging of living... 
MOUSE-BRAIN | HEART | OSTEOCYTES | NEURONS IN-VIVO | PHYSICS, APPLIED | CAENORHABDITIS-ELEGANS | INTRACELLULAR CALCIUM | LIGHT-SHEET MICROSCOPY | RESOLUTION | ILLUMINATION MICROSCOPY | CONTRAST | OPTICS | Firing | Planes | Microscopy | Imaging | High speed | Illumination | Excitation | Confocal | Three dimensional
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6. Full Text Axial plane optical microscopy
by Li, Tongcang and Ota, Sadao and Kim, Jeongmin and Wong, Zi Jing and Wang, Yuan and Yin, Xiaobo and Zhang, Xiang
Scientific Reports, ISSN 2045-2322, 2014, Volume 4, Issue 1, p. 7253
We present axial plane optical microscopy (APOM) that can, in contrast to conventional microscopy, directly image a sample's cross-section parallel to the... 
TOMOGRAPHY | CELLS | MULTIDISCIPLINARY SCIENCES | LIGHT-SHEET MICROSCOPY | ILLUMINATION MICROSCOPY | DIFFRACTION | SYSTEMS | BRAIN | EMBRYOS | SECTIONING MICROSCOPY | MECHANOTRANSDUCTION | Reproducibility of Results | Microscopy - instrumentation | Sensitivity and Specificity | Imaging, Three-Dimensional - instrumentation | Image Enhancement - instrumentation | Equipment Design | Equipment Failure Analysis | Lenses | Neuroimaging | Illumination | Scanning | Microscopy | Microscopes | Brain slice preparation
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7. Full Text The light-sheet microscopy revolution
by Girkin, J.M and Carvalho, M.T
Journal of Optics (United Kingdom), ISSN 2040-8978, 05/2018, Volume 20, Issue 5, p. 53002
This paper reviews the rapid advances that have been made in one form of optical biological imaging in the last decade, namely that of light sheet microscopy.... 
in vivo imaging | 3D biological imaging | selective plane illumination microscopy | optical microscopy | light-sheet microscopy | SPIM | EMBRYONIC-DEVELOPMENT | PLANE ILLUMINATION MICROSCOPY | SUPERRESOLUTION MICROSCOPY | ADAPTIVE OPTICS | STRUCTURED-ILLUMINATION | FLUORESCENCE MICROSCOPY | BESSEL BEAMS | IN-VIVO | OPTICS | WIDE-FIELD | CORRELATION SPECTROSCOPY
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8. Full Text Correlative two-photon and light sheet microscopy
by Silvestri, Ludovico and Allegra Mascaro, Anna Letizia and Costantini, Irene and Sacconi, Leonardo and Pavone, Francesco Saverio
Methods, ISSN 1046-2023, 03/2014, Volume 66, Issue 2, pp. 268 - 272
Information processing inside the central nervous system takes place on multiple scales in both space and time. A single imaging technique can reveal only a... 
Two-photon fluorescence microscopy | Brain imaging | Light sheet microscopy | Correlative microscopy | MOUSE-BRAIN | SPINE GROWTH | NEOCORTEX IN-VIVO | STRUCTURAL PLASTICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | ELECTRON-MICROSCOPY | ADULT NEOCORTEX | SCANNING MICROSCOPY | VISUAL-CORTEX | SHG MICROSCOPY | ILLUMINATION MICROSCOPY | Animals | Microscopy, Fluorescence - methods | Green Fluorescent Proteins - biosynthesis | Somatosensory Cortex - blood supply | Mice, Transgenic | Somatosensory Cortex - cytology | Dendrites - ultrastructure | Mice | Microscopy, Confocal - methods | Microscope and microscopy
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9. Full Text Phototoxicity in live fluorescence microscopy, and how to avoid it
by Icha, Jaroslav and Weber, Michael and Waters, Jennifer C and Norden, Caren
BioEssays, ISSN 0265-9247, 08/2017, Volume 39, Issue 8, p. 1700003
Phototoxicity frequently occurs during live fluorescence microscopy, and its consequences are often underestimated. Damage to cellularmacro molecules upon... 
live imaging | photobleaching | reactive oxygen species | photodamage | phototoxicity | light sheet fluorescence microscopy | selective plane illumination | LONG-TERM | 2-PHOTON EXCITATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIGHT-SHEET MICROSCOPY | INDUCED CELL-DAMAGE | BIOLOGY | ILLUMINATION MICROSCOPY | HIGH-SPEED | EXPOSURE | LIVING CELLS | Biological Assay - methods | Reactive Oxygen Species - metabolism | Microscopy, Fluorescence - methods | Photobleaching | Physiological aspects | Photobiology | Analysis | Fluorescence microscopy | Methods | Focal plane | Microscopy | Macromolecules | Light | Fluorescence | Phototoxicity | Illumination | Biological activity | Constraining
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10. Full Text Light-Sheet Microscopy in Neuroscience
by Hillman, Elizabeth M.C and Voleti, Venkatakaushik and Li, Wenze and Yu, Hang
ANNUAL REVIEW OF NEUROSCIENCE, VOL 42, ISSN 0147-006X, 7/2019, Volume 42, Issue 1, pp. 295 - 313
Light-sheet microscopy is an imaging approach that offers unique advantages for a diverse range of neuroscience applications. Unlike point-scanning techniques... 
GCaMP | microscopy | functional imaging | light sheet | tissue clearing | EXCITATION | PLANE ILLUMINATION MICROSCOPY | RECONSTRUCTION | RESOLUTION | TISSUE | NEUROSCIENCES | FLUORESCENCE MICROSCOPY | DEEP | DECONVOLUTION | PROTEINS | WIDE-FIELD | Physiological aspects | Neural circuitry | Microscope and microscopy | Methods | Neuroimaging | Neurosciences | Embryogenesis | Scanning | Microscopy | Light | Nervous system | Microscopes | Photobleaching
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11. Full Text Technical implementations of light sheet microscopy
by Elisa, Zagato and Toon, Brans and De Smedt, Stefaan C and Katrien, Remaut and Kristiaan, Neyts and Kevin, Braeckmans and Cella Zanacchi, Francesca
Microscopy Research and Technique, ISSN 1059-910X, 09/2018, Volume 81, Issue 9, pp. 941 - 958
Fluorescence‐based microscopy is among the most successful methods in biological studies. It played a critical role in the visualization of subcellular... 
light sheet microscopy | SPIM | EXCITATION | PLANE ILLUMINATION MICROSCOPY | STED-SPIM | ANATOMY & MORPHOLOGY | RESOLUTION | CROSS-CORRELATION SPECTROSCOPY | MICROSCOPY | FLUORESCENCE MICROSCOPY | BESSEL BEAMS | BIOLOGY | FLOW-CYTOMETRY | HIGH-SPEED | EMBRYOS | Microscope and microscopy | Image resolution | Optical sectioning | Fluorescence | Tissues | Drug screening | Chemical compounds | Sectioning | Microscopy | Light | Fluorophores | Data collection | Microscopes | Fluorescence microscopy | Cellular structure | Photobleaching
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12. Full Text K-domain transform based three-dimensional microscopy
by Zhang, Xuedan and Liu, Cheng and Zhu, Jianqiang
Applied Physics Letters, ISSN 0003-6951, 11/2018, Volume 113, Issue 22, p. 221106
A K-domain transform based three-dimensional microscopy technique is proposed. By illuminating an object with a light sheet along the optical axis and... 
TOMOGRAPHY | PHYSICS, APPLIED | LIGHT SHEET MICROSCOPY | TILTED PLANES | RESOLUTION | DIFFRACTION | SCALE | FIELD FLUORESCENCE MICROSCOPY | EQUATION | IMAGE-FORMATION
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13. Full Text Adaptive particle representation of fluorescence microscopy images
by Cheeseman, Bevan L and Günther, Ulrik and Gonciarz, Krzysztof and Susik, Mateusz and Sbalzarini, Ivo F
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5160 - 13
Modern microscopes create a data deluge with gigabytes of data generated each second, and terabytes per day. Storing and processing this data is a severe... 
CONTRAST | MULTIDISCIPLINARY SCIENCES | FLOW | LIGHT-SHEET MICROSCOPY | ADAPTATION | Compression | Image processing | Data compression | Fluorescence | Data processing | Image compression | Pixels | Image quality | Storage | Microscopy | Representations | Microscopes | Fluorescence microscopy
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14. Full Text 3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy
by Gao, Liang and Shao, Lin and Chen, Bi-Chang and Betzig, Eric
Nature Protocols, ISSN 1754-2189, 2014, Volume 9, Issue 5, pp. 1083 - 1101
3D live imaging is important for a better understanding of biological processes, but it is challenging with current techniques such as spinning-disk confocal... 
DEEP | LIGHT-SHEET MICROSCOPY | RESOLUTION | BIOCHEMICAL RESEARCH METHODS | LIMIT | STRUCTURED-ILLUMINATION | EMBRYOS | Models, Theoretical | Microscopy, Fluorescence - methods | Single-Cell Analysis - methods | Imaging, Three-Dimensional - instrumentation | Imaging, Three-Dimensional - methods | Cells - metabolism | Microscopy, Fluorescence - instrumentation | Lighting - methods | Photobleaching | Diagnostic imaging | Research | Fluorescence microscopy | Methods
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