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Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7409, pp. 106 - 110
Medulloblastomas are themost commonmalignant brain tumours in children(1). Identifying and understanding the genetic events that drive these tumours is... 
COMPLEX | STRUCTURAL BASIS | LANDSCAPE | CHILDHOOD | MULTIDISCIPLINARY SCIENCES | GENES | Transcription Factors - chemistry | Humans | Hedgehog Proteins - metabolism | Wnt Proteins - metabolism | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | TCF Transcription Factors - metabolism | Patched Receptors | Cerebellar Neoplasms - classification | DEAD-box RNA Helicases - metabolism | Medulloblastoma - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Child | DEAD-box RNA Helicases - chemistry | DNA Helicases - genetics | Intracellular Signaling Peptides and Proteins - genetics | DNA Helicases - chemistry | Histone-Lysine N-Methyltransferase - genetics | Signal Transduction | Models, Molecular | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nuclear Proteins - chemistry | beta Catenin - metabolism | Genome, Human - genetics | beta Catenin - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Histone Methyltransferases | Histone-Lysine N-Methyltransferase - metabolism | LIM Domain Proteins - genetics | Medulloblastoma - classification | Patched-1 Receptor | Receptors, Cell Surface - genetics | Medulloblastoma | Physiological aspects | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Metastasis | DNA sequencing | Cancer
Journal Article
Blood, ISSN 0006-4971, 03/2016, Volume 127, Issue 10, pp. 1325 - 1335
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2017, Volume 127, Issue 1, pp. 215 - 229
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 04/2015, Volume 96, Issue 4, pp. 597 - 611
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide and the fourth most lethal cancer in China. However, although genomic... 
POPULATION | DNA | SUSCEPTIBILITY | GENETICS & HEREDITY | ARCHITECTURE | WIDE ASSOCIATION | DIFFERENTIATION | IDENTIFICATION | SOMATIC MUTATIONS | HUMAN CANCER | BREAST | Immunohistochemistry | Carcinoma, Squamous Cell - genetics | Humans | Molecular Sequence Data | Immunoblotting | Gene Knockdown Techniques | CREB-Binding Protein - genetics | Polycomb Repressive Complex 1 - genetics | Tetrazolium Salts | APOBEC-1 Deaminase | Ligases | Base Sequence | China | Tumor Suppressor Proteins - genetics | Thiazoles | Patched Receptors | Real-Time Polymerase Chain Reaction | Esophageal Squamous Cell Carcinoma | Genetic Predisposition to Disease - genetics | Cytidine Deaminase - genetics | In Situ Hybridization, Fluorescence | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Mutation - genetics | Ubiquitin Thiolesterase - genetics | Sequence Analysis, DNA | Genome, Human - genetics | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Analysis of Variance | Esophageal Neoplasms - genetics | Polycomb-Group Proteins - genetics | Cell Line, Tumor | LIM Domain Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Squamous cell carcinoma | Genetic aspects | Gene mutations | Identification and classification | Esophageal cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 45, pp. 18273 - 18280
During cardiogenesis, Fibroblast Growth Factor (Fgf10) is expressed in the anterior second heart field. Together with Fibroblast growth factor 8 (Fgf8), Fgf10... 
Heart | Transgenic animals | Heart ventricles | Genes | Myocardium | Promoter regions | Transgenes | Embryos | Progenitor cells | Binding sites | Transcriptional regulation | Mouse embryo | TRANSCRIPTION FACTORS | CELLS | ARTERIAL POLE | MOUSE HEART | transcriptional regulation | MULTIDISCIPLINARY SCIENCES | OUTFLOW TRACT | mouse embryo | ENHANCER | ISL1 | DIFFERENTIATION | EXPRESSION | FGF10 | Protein Binding - genetics | LIM-Homeodomain Proteins - metabolism | Heart - embryology | Homeodomain Proteins - metabolism | Molecular Sequence Data | Chromosomes, Artificial, Bacterial - genetics | Gene Expression Regulation, Developmental | Base Pairing - genetics | Base Sequence | Myocardium - metabolism | Transcription, Genetic | Fibroblast Growth Factor 10 - genetics | Binding Sites | Fibroblast Growth Factor 10 - metabolism | Transgenes - genetics | Mice, Transgenic | Transcription Factors - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Homeodomain Proteins - genetics | Regulatory Sequences, Nucleic Acid - genetics | T-Box Domain Proteins - metabolism | Transcription Factors - metabolism | Homeobox Protein Nkx-2.5 | LIM-Homeodomain Proteins - genetics | Animals | Genes, Switch - genetics | Models, Biological | Mice | Physiological aspects | Fibroblast growth factors | Genetic aspects | Research | Genetic transcription | Genetic regulation | Health aspects | Heart muscle | Regulatory Sequences, Nucleic Acid | Cellular Biology | Life Sciences | Chromosomes, Artificial, Bacterial | Genes, Switch | Down-Regulation | Base Pairing | Fibroblast Growth Factor 10 | Homeodomain Proteins | Protein Binding | LIM-Homeodomain Proteins | Transcription Factors | T-Box Domain Proteins | Biological Sciences
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 01/2014, Volume 19, Issue 1, pp. 41 - 49
Journal Article
Science Signaling, ISSN 1945-0877, 09/2013, Volume 6, Issue 292, pp. ra81 - ra81
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 2012, Volume 31, Issue 1, pp. 58 - 58
Background: This study was performed to investigate the effect of microRNA-203 (miR-203) on cell proliferation and migration in triple-negative breast cancer... 
Lim and SH3 domain protein 1 | MiR-203 | Proliferation | Migration | baculoviral IAP repeat-containing protein 5 | Triple-negative breast cancer | APOPTOSIS | Lim and SH3 domain | SURVIVIN | protein 1 | LIM | INHIBITION | GENE | ONCOLOGY | EXPRESSION | RNA, Small Interfering - genetics | Receptors, Estrogen - metabolism | Cytoskeletal Proteins - genetics | Inhibitor of Apoptosis Proteins - genetics | Humans | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | LIM Domain Proteins - biosynthesis | MicroRNAs - metabolism | LIM Domain Proteins - metabolism | RNA, Messenger - metabolism | Cell Movement - genetics | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | Transfection | Cytoskeletal Proteins - metabolism | Female | Inhibitor of Apoptosis Proteins - metabolism | Cell Growth Processes - genetics | Cytoskeletal Proteins - biosynthesis | Inhibitor of Apoptosis Proteins - biosynthesis | Down-Regulation | RNA, Messenger - genetics | MicroRNAs - biosynthesis | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | LIM Domain Proteins - genetics | Adaptor Proteins, Signal Transducing - biosynthesis | MicroRNAs - genetics | Adaptor Proteins, Signal Transducing - metabolism | RNA, Small Interfering - administration & dosage | Cell proliferation | Medicine, Experimental | Medical research | Breast cancer | MicroRNA | Luciferase | Proteins | Cell culture | Experiments | Cell adhesion & migration | Triple-negative breast cancer, MiR-203 | baculoviral IAP repeat-containing protein 5, Lim and SH3 domain protein 1, Proliferation, Migration
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30172 - 30180
Background: Vesiculation of tubular recycling endosomes is essential for the recycling of receptors and lipids to the plasma membrane. Results: A novel... 
Membrane Trafficking | Membrane Biogenesis | Subcellular Organelles | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | EHD1 INTERACT | Cell Biology | Membrane Recycling | Protein Sorting | Vesicles | TRANSPORT | Liposomes | Receptor Recycling | CAVEOLAE | ASSOCIATION | Endosomes | INSIGHTS | Adaptor Proteins, Signal Transducing - chemistry | Cytoskeletal Proteins - genetics | Vesicular Transport Proteins - metabolism | Humans | LIM Domain Proteins - metabolism | Endosomes - metabolism | DNA-Binding Proteins - metabolism | Endosomes - ultrastructure | Carrier Proteins - chemistry | Cytoskeletal Proteins - metabolism | Nuclear Proteins - genetics | LIM Domain Proteins - chemistry | Endosomes - genetics | Vesicular Transport Proteins - genetics | Adenosine Triphosphatases - metabolism | Nuclear Proteins - metabolism | Vesicular Transport Proteins - chemistry | Cytoskeletal Proteins - chemistry | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Intracellular Membranes - chemistry | Carrier Proteins - genetics | Carrier Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Endosomes - chemistry | Adenosine Triphosphatases - chemistry | LIM Domain Proteins - genetics | Adenosine Triphosphatases - genetics | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Intracellular Membranes - metabolism
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2012, Volume 18, Issue 5, pp. 766 - 773
Journal Article
12.