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Nature (London), ISSN 1476-4687, 07/2012, Volume 488, Issue 7409, pp. 106 - 110
Medulloblastomas are themost commonmalignant brain tumours in children(1). Identifying and understanding the genetic events that drive these tumours is critical... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Transcription Factors - chemistry | Humans | Hedgehog Proteins - metabolism | Wnt Proteins - metabolism | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | TCF Transcription Factors - metabolism | Patched Receptors | Cerebellar Neoplasms - classification | DEAD-box RNA Helicases - metabolism | Medulloblastoma - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Child | DEAD-box RNA Helicases - chemistry | DNA Helicases - genetics | Intracellular Signaling Peptides and Proteins - genetics | DNA Helicases - chemistry | Histone-Lysine N-Methyltransferase - genetics | Signal Transduction | Models, Molecular | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nuclear Proteins - chemistry | beta Catenin - metabolism | Genome, Human - genetics | beta Catenin - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Histone Methyltransferases | Histone-Lysine N-Methyltransferase - metabolism | LIM Domain Proteins - genetics | Medulloblastoma - classification | Patched-1 Receptor | Receptors, Cell Surface - genetics | Medulloblastoma | Physiological aspects | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Metastasis | DNA sequencing | Cancer | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, pp. e0183081 - e0183081
Ciliopathies are a group of rare disorders characterized by a high genetic and phenotypic variability, which complicates their molecular diagnosis... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Male | LIM Domain Proteins - metabolism | Ciliopathies - diagnosis | DNA-Binding Proteins - metabolism | Exome | Ciliopathies - genetics | Female | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Eye Proteins - genetics | Microfilament Proteins - genetics | Biomarkers - metabolism | Gene Expression | Cilia - pathology | Membrane Proteins - genetics | Genotype | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Cilia - metabolism | Nerve Tissue Proteins - metabolism | Proteins - genetics | Transcription Factors - metabolism | Phenotype | Proteins - metabolism | Eye Proteins - metabolism | LIM Domain Proteins - genetics | Consanguinity | High-Throughput Nucleotide Sequencing | Genome, Human | Cell Cycle Proteins | Ciliopathies - pathology | Usage | Genetic disorders | Gene mutations | Cilia and ciliary motion | Exome sequencing | Research | Diagnosis | Health aspects | Pediatrics | Filtration | Genetic variability | Genes | Genomics | Disorders | Bardet-Biedl syndrome | Patients | Genetic screening | Gene sequencing | Studies | Filters | Hospitals | Diagnostic software | Strategy | Diagnostic systems | Mutation | Bioinformatics | Genetic counselling | Deoxyribonucleic acid--DNA | Methods | Cilia | Index Medicus | Ciliopathies | Genome analysis | Deoxyribonucleic acid | DNA
Journal Article
Blood, ISSN 1528-0020, 03/2016, Volume 127, Issue 10, pp. 1325 - 1335
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2009, Volume 284, Issue 19, pp. 13202 - 13212
.... In this study, we show that a four-and-a-half LIM domain protein 2 (FHL2) inhibits transcriptional activation of vSMC-specific genes mediated by the bone morphogenetic... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Serum Response Factor - genetics | Muscle, Smooth, Vascular - metabolism | Homeodomain Proteins - metabolism | Humans | Transcriptional Activation | Cercopithecus aethiops | RNA Polymerase II - metabolism | RNA, Messenger - metabolism | Pulmonary Artery - metabolism | Chromatin Immunoprecipitation | Muscle Proteins - metabolism | Trans-Activators - genetics | Adenoviridae - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | Muscle Proteins - physiology | Promoter Regions, Genetic | Transcription Factors - physiology | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Serum Response Factor - metabolism | RNA, Messenger - genetics | Cells, Cultured | Aorta, Thoracic - metabolism | Chromatin Assembly and Disassembly | Nuclear Proteins - metabolism | Transcription Factors - genetics | Muscle, Smooth, Vascular - cytology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Bone Morphogenetic Protein Receptors, Type II - metabolism | Homeodomain Proteins - genetics | Mice, Knockout | Pulmonary Artery - cytology | Muscle Proteins - genetics | Transcription Factors - metabolism | Aorta, Thoracic - cytology | DNA Helicases - metabolism | Phenotype | Animals | Fluorescent Antibody Technique | LIM-Homeodomain Proteins | RNA Polymerase II - genetics | Trans-Activators - metabolism | Mice | Homeodomain Proteins - physiology | COS Cells | Index Medicus
Journal Article
American journal of human genetics, ISSN 0002-9297, 04/2015, Volume 96, Issue 4, pp. 597 - 611
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide and the fourth most lethal cancer in China. However, although genomic... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Immunohistochemistry | Carcinoma, Squamous Cell - genetics | Humans | Molecular Sequence Data | Immunoblotting | Gene Knockdown Techniques | CREB-Binding Protein - genetics | Polycomb Repressive Complex 1 - genetics | Tetrazolium Salts | APOBEC-1 Deaminase | Ligases | Base Sequence | China | Tumor Suppressor Proteins - genetics | Thiazoles | Patched Receptors | Real-Time Polymerase Chain Reaction | Esophageal Squamous Cell Carcinoma | Genetic Predisposition to Disease - genetics | Cytidine Deaminase - genetics | In Situ Hybridization, Fluorescence | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Mutation - genetics | Ubiquitin Thiolesterase - genetics | Sequence Analysis, DNA | Genome, Human - genetics | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Analysis of Variance | Esophageal Neoplasms - genetics | Polycomb-Group Proteins - genetics | Cell Line, Tumor | LIM Domain Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Squamous cell carcinoma | Genetic aspects | Gene mutations | Identification and classification | Esophageal cancer | Chromatin | Genomics | DNA damage | Genetics | Mutation | Cancer | Tumors | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2017, Volume 127, Issue 1, pp. 215 - 229
Journal Article
Journal Article