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Development (Cambridge, England), ISSN 0950-1991, 02/2018, Volume 145, Issue 3, pp. e0303 - e0303
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 04/2018, Volume 58, Issue 4, pp. 482 - 491
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 02/2005, Volume 16, Issue 2, pp. 649 - 664
Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all eukaryotes. In vitro, ADF/cofilins promote actin dynamics by... 
RNA INTERFERENCE | LATRUNCULIN-A | PHOSPHORYLATION | LEADING-EDGE | LIM-KINASE | DYNAMICS | ADF/COFILIN | FILAMENT TURNOVER | BINDING PROTEIN | MOTILITY | CELL BIOLOGY
Journal Article
by Xu, XH and Gera, N and Li, HY and Yun, M and Zhang, LY and Wang, YH and Wang, QJ and Jin, T
MOLECULAR BIOLOGY OF THE CELL, ISSN 1059-1524, 03/2015, Volume 26, Issue 5, pp. 874 - 886
Chemotaxis requires precisely coordinated polymerization and depolymerization of the actin cytoskeleton at leading fronts of migrating cells. However, GPCR... 
CELLS | ACTIVATION | ACTIN REORGANIZATION | PHOSPHORYLATION | ROLES | DOWNSTREAM | LIM-KINASE | RECEPTOR | POLARIZATION | FAMILY | CELL BIOLOGY
Journal Article
ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 05/2016, Volume 68, Issue 5, pp. 1272 - 1280
Objective. Behcet's disease (BD) is a systemic inflammatory disease with an incompletely understood etiology. Despite the identification of multiple common... 
GLYCOSYLASE | POPULATION | ACTIVATION | LIM-KINASE 2 | INTERACTION NETWORKS | VASCULITIS | RHEUMATOLOGY | LARGE GENE LISTS | ASSOCIATION | ENDOTHELIAL GROWTH-FACTOR | PREDICTION
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2018, Volume 17, Issue 11, pp. 1381 - 1389
LIMKs (LIMK1 and LIMK2) are serine/threonine protein kinases that involve in various cellular activities such as cell migration, morphogenesis and cytokinesis.... 
embryo development | blastocyst | LIMK1/2 | actin | FERTILIZATION | CYTOSKELETON | LIM-KINASE | PORCINE OOCYTE MATURATION | CELL BIOLOGY | EARLY COMPACTION | DYNAMICS | ADF/COFILIN | CELL | COFILIN PHOSPHORYLATION
Journal Article
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 01/2015, Volume 6, Issue 1, pp. 84 - 88
The structure of LX7101, a dual LIM-kinase and ROCK inhibitor for the treatment of ocular hypertension and associated glaucoma, is disclosed. Previously... 
kinase | ROCK inhibitor | LIM-kinase | LX7101 | glaucoma | CHEMISTRY, MEDICINAL | IDENTIFICATION | FAMILY
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 08/2019, Volume 116, pp. 109054 - 109054
Depression is a common disease that endangers people’s physical and mental health. Traditional Chinese medicine has advantages in treating the emotional and... 
Cofilin | Depression | Rac1 | Baicalin | Synaptic plasticity | MEDICINE, RESEARCH & EXPERIMENTAL | SYNAPTIC FUNCTION | PHOSPHORYLATION | LIM-KINASE | GROWTH | PHARMACOLOGY & PHARMACY | MORPHOLOGY | PLASTICITY
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 1/2018, Volume 38, Issue 1, pp. 87 - 102
Intracerebral hemorrhage (ICH) represents the deadliest subtype of all strokes. The development of brain edema, a consequence of blood–brain barrier (BBB)... 
Cortactin | intracerebral hemorrhage | PDGFR-β | LIM kinase | stress fibers | PDGFR-beta | LOCALIZATION | RHO KINASE | PERMEABILITY | ACTIN | NEUROSCIENCES | BETA | GROWTH-FACTOR RECEPTOR | IN-VIVO | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | VE-CADHERIN | ADHERENS JUNCTIONS | HEMATOLOGY | Index Medicus | Original
Journal Article
Journal Article
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 01/2005, Volume 118, Issue 1, pp. 19 - 26
Cofilin has emerged as a key regulator of actin dynamics at the leading edge of motile cells. Through its actin-severing activity, it creates new actin barbed... 
FILAMENT BARBED ENDS | F-ACTIN | MAMMARY ADENOCARCINOMA | LAMELLIPOD EXTENSION | PHOSPHOLIPASE-C | LIM-KINASE | INTERACTING PROTEIN-1 | NONMUSCLE CELLS | CELL BIOLOGY | Arp2/3 complex | ACTIN-DEPOLYMERIZING FACTOR | stimulated protrusion model | chemotaxis
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 08/2018, Volume 9, pp. 1090 - 1090
The proliferation and migration of intestinal epithelial cell is important to the barrier integrity of intestinal epithelium. Cucurbitacin E (CuE) is one of... 
Cell proliferation | Actin | Cell cycle | Intestinal epithelial cells | LIM kinase | Cofilin | Cucurbitacin E | Cell migration | Research | cell migration | intestinal epithelial cells | cofilin | cell proliferation | cell cycle
Journal Article
Frontiers in physiology, ISSN 1664-042X, 2018, Volume 9, p. 1090
The proliferation and migration of intestinal epithelial cell is important to the barrier integrity of intestinal epithelium. Cucurbitacin E (CuE) is one of... 
Journal Article
Nature Neuroscience, ISSN 1097-6256, 06/2012, Volume 15, Issue 6, pp. 891 - 896
Journal Article