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Biomedicine & Pharmacotherapy, ISSN 0753-3322, 07/2019, Volume 115, pp. 108956 - 108956
Non-small cell lung cancer (NSCLC) is demonstrated as one of the most common malignant tumors and accounts for about 25% of cancer-related deaths each year.... 
miR-4319 | YAP | NSCLC | LIN28 | RFX5
Journal Article
03/2014
CNS-PNETs are rare, aggressive, paediatric embryonal brain tumours that are poorly studied. We recently identified an aggressive sub-group of CNS-PNETs... 
Primitive Neuro-ectodermal Tumours | CNS-PNET | 0992 | LIN28 | OLIG2
Dissertation
Cell and Tissue Research, ISSN 0302-766X, 8/2016, Volume 365, Issue 2, pp. 319 - 330
The commonly used inhalational anesthetic, sevoflurane, can cause toxicity to the central nervous system of the developing fetus. Lin28 has been reported to... 
Human Genetics | Sevoflurane | let-7a -Lin28 pathway | Self-renewal | Biomedicine | Mouse embryonic stem cell | Proteomics | Molecular Medicine | Neurogenesis | let-7a-Lin28 pathway | LIN28 | PLURIPOTENCY | PROLIFERATION | NEUROTOXICITY | CELL BIOLOGY | ANESTHESIA | CIRCUITRY | METABOLISM | BIOLOGY | let-7 alpha-Lin28 pathway | AXIS | Apoptosis - drug effects | Cell Survival - genetics | Apoptosis - genetics | Male | MicroRNAs - metabolism | Mouse Embryonic Stem Cells - cytology | Neurons - cytology | Brain - growth & development | Cell Self Renewal - drug effects | Brain - metabolism | Cell Self Renewal - genetics | Cell Differentiation - genetics | Anesthesia | Female | Neurons - metabolism | Neurons - drug effects | Biomarkers - metabolism | Cell Survival - drug effects | Mice, Inbred C57BL | Embryonic Development - genetics | Gene Expression Regulation, Developmental - drug effects | Up-Regulation - genetics | Methyl Ethers - pharmacology | Signal Transduction - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Brain - drug effects | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Mice | Embryonic Development - drug effects | RNA-Binding Proteins - metabolism | Pregnancy | Anesthetics | Cell differentiation | Embryonic stem cells | Pregnant women | Pharmacology | Gene expression | Embryos | Stem cells | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17386 - 17397
Journal Article
Journal of the Royal Society Interface, ISSN 1742-5689, 12/2014, Volume 11, Issue 101, pp. 20140962 - 20140962
Journal Article
Cell Reports, ISSN 2211-1247, 06/2018, Volume 23, Issue 10, pp. 3091 - 3101
LIN28 is an RNA-binding protein that regulates the maturation of the let-7 family of microRNAs by bipartite interactions with let-7 precursors through its two... 
LIN28 inhibitor | TPEN | let-7 | LI71 | LIN28 | TUT4 | oligouridylation | pre-let-7 | TUTase | 5-(methylamino)nicotinic acid | APOPTOSIS | STEM-CELLS | MODELS | TUMOR | CANCER CELL-GROWTH | MATURATION | SUFFICIENT | FEEDBACK LOOP | MICRORNA | CELL BIOLOGY | Index Medicus
Journal Article
by Kang, M and Lee, KH and Lee, HS and Jeong, CW and Ku, JH and Kim, HH and Kwak, C
PLOS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9
We examined the anti-cancer effects and molecular mechanism of simvastatin in human castration-resistant prostate cancer (CRPC) cells, particularly focused on... 
APOPTOSIS | ACTIVATION | PRODUCTS | LIN28 | MULTIDISCIPLINARY SCIENCES | GROWTH | MEVALONATE PATHWAY | STATINS | TUMORS
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 12/2015, Volume 75, Issue 24, pp. 5206 - 5210
This report summarizes information presented at the 2015 Keystone Symposium on "MicroRNAs and Noncoding RNAs in Cancer." Nearly two decades after the discovery... 
APOPTOSIS | GENE | ONCOLOGY | LIN28 | CERNAS | LET-7 | IDENTIFICATION | MICRORNA | Animals | Neoplasms - genetics | Humans | RNA, Untranslated | Index Medicus
Journal Article
Journal Article
Chinese Journal of Clinical Oncology, ISSN 1000-8179, 04/2014, Volume 41, Issue 8, pp. 530 - 533
Journal Article