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JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 1665 - 1672
Macrocyclic peptides are considered large enough to inhibit"undruggable" targets, but the design of passively cell-permeable molecules in this space remains a... 
BARRIER DOMAIN | ESTIMATE SOLUBILITY | CHEMISTRY, MEDICINAL | LIPID-BILAYER-MEMBRANES | PERMEABILITY | ARTIFICIAL MEMBRANES | NATURAL-PRODUCTS | MACROCYCLES | DEVELOPMENT SETTINGS | CYCLIC-PEPTIDES | DISCOVERY
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 06/2012, Volume 8, Issue 6, pp. 509 - 517
Metabolic pathways may seem arbitrary and unnecessarily complex. In many cases, a chemist might devise a simpler route for the biochemical transformation, so... 
EVOLUTIONARY OPTIMIZATION | AMINO-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | MIXED-ACID FERMENTATION | METHYLGLYOXAL SYNTHASE | ANAEROBIC-BACTERIA | GLYCINE REDUCTASE | CELL-METABOLISM | MILD AQUEOUS CONDITIONS | LIPID BILAYER-MEMBRANES
Journal Article
ACCOUNTS OF CHEMICAL RESEARCH, ISSN 0001-4842, 05/2018, Volume 51, Issue 5, pp. 1106 - 1116
CONSPECTUS: Ever since the first molecular mechanics computer simulations of biological molecules became possible, there has been the dream to study all... 
GENERALIZED BORN THEORY | FOLDING SIMULATIONS | SOLVENT MODELS | LIPID-BILAYER MEMBRANES | TRANSMEMBRANE-HELIX | DIELECTRIC ENVIRONMENTS | FORCE-FIELD | IMPLICIT-MEMBRANE | PORE FORMATION | ANTIMICROBIAL PEPTIDES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Applied Physics Letters, ISSN 0003-6951, 08/2011, Volume 99, Issue 9, pp. 093105 - 093105-3
We integrated an ultra-broadband microwave circuit for direct sampling of single α-Hemolysin pores in a suspended bilipid membrane. Simultaneous direct current... 
PHYSICS, APPLIED | LIPID BILAYER-MEMBRANES | MOLECULAR ADAPTER
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2016, Volume 55, Issue 26, pp. 7550 - 7550
Hydrazone‐activated polymers with a consistent degree of polymerization but with different post‐polymerization functionalization were employed as scaffolds for... 
siRNA delivery | polymers | lipid bilayer membranes | supramolecular chemistry | vesicles | Polymerization | Polymers | siRNA | Degree of polymerization | Scaffolds
Journal Article
Langmuir, ISSN 0743-7463, 03/2003, Volume 19, Issue 5, pp. 1681 - 1691
The adsorption kinetics of small unilamellar egg-yolk phosphatidylcholine vesicles was investigated by the quartz crystal microbalance-dissipation (QCM-D)... 
CYTOCHROME-C | UNILAMELLAR VESICLES | ATOMIC-FORCE MICROSCOPY | PROTEIN ADSORPTION | SOLID SUPPORTS | CHEMISTRY, PHYSICAL | QUARTZ-CRYSTAL MICROBALANCE | PHOSPHOLIPID-BILAYERS | PLANAR MEMBRANES | LIPID BILAYER-MEMBRANES | PLASMON RESONANCE
Journal Article
Journal of the Optical Society of America B: Optical Physics, ISSN 0740-3224, 05/2012, Volume 29, Issue 5, pp. 959 - 964
A four-layer waveguide structure comprising a dielectric substrate, a metal layer, a left-handed material (LHM) as a guiding layer, and a cladding is... 
SENSITIVITY | METAMATERIAL | LIPID-BILAYER-MEMBRANES | OPTICS | RESONANCE | Reflectivity | Reflectance curves | Mathematical analysis | Waveguides | Reflection coefficient | Sensors | Dipping | Reflectance
Journal Article
Drug Delivery and Translational Research, ISSN 2190-393X, 6/2015, Volume 5, Issue 3, pp. 231 - 242
Cholesterol plays a strategic role in liposome composition; however, the quantity used to achieve an appropriate formulation has not been yet clarified.... 
Biomedicine | Pharmaceutical Sciences/Technology | AFM | Mathematical modelling | Liposomes | Cholesterol | Controlled release | MEDICINE, RESEARCH & EXPERIMENTAL | PERMEABILITY | VESICLES | INFRARED-SPECTROSCOPY | LIPID BILAYER-MEMBRANES | MODEL MEMBRANES | ATOMIC-FORCE MICROSCOPY | TEMPERATURE | KINETICS | PHARMACOLOGY & PHARMACY | ENCAPSULATION EFFICIENCY | MODULATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 13, pp. E2545 - E2546
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 15, pp. 6731 - 6736
Journal Article
Chemical Reviews, ISSN 0009-2665, 04/2006, Volume 106, Issue 4, pp. 1462 - 1477
  This paper addresses the aqueous interfaces of nano- and microsize particles in aqueous solutions, commonly referred to as colloids, as examined by means of... 
AIR-WATER-INTERFACE | 2ND HARMONIC-GENERATION | ION-TRANSPORT | NONLINEAR-OPTICAL PROPERTIES | SURFACE COMPLEXATION | SUM-FREQUENCY GENERATION | TITANIUM-DIOXIDE FILMS | HYPER-RAYLEIGH SCATTERING | VIBRATIONAL SPECTROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | LIPID BILAYER-MEMBRANES | Water | Interfaces | Chemistry | Experiments | Spectrum analysis
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 06/2019, Volume 178, pp. 404 - 411
Previous research has shown that ectoines fluidize lipid monolayers by increasing the liquid expanded region in DPPC monolayers and also decreasing the line... 
Compatible solutes | Lipid bilayer membranes | Giant unilamellar vesicles | Osmolytes | Phase transition | MATERIALS SCIENCE, BIOMATERIALS | CHEMISTRY, PHYSICAL | MODEL MEMBRANES | LIPID-BILAYERS | BIOPHYSICS | RAFTS | COMPATIBLE SOLUTE ECTOINE | STRESS
Journal Article
Langmuir, ISSN 0743-7463, 01/2018, Volume 34, Issue 4, pp. 1691 - 1699
Interaction of functional nanoparticles with cells and model biomembranes has been widely studied to evaluate the effectiveness of the particles as potential... 
MATERIALS SCIENCE, MULTIDISCIPLINARY | CHARGED NANOPARTICLES | CHEMISTRY, PHYSICAL | BOUNDARY REGION | FLUORESCENCE CORRELATION SPECTROSCOPY | CHEMISTRY, MULTIDISCIPLINARY | QUANTUM DOTS | ATOMIC-FORCE MICROSCOPY | STIMULATED-EMISSION | PORE-FORMING PROTEINS | LIPID-BILAYER MEMBRANES | UPTAKE MECHANISM | LATERAL DIFFUSION | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7481, pp. 103 - 107
Human body-surface epithelia coexist in close association with complex bacterial communities and are protected by a variety of antibacterial proteins. C-type... 
MULTIDISCIPLINARY SCIENCES | CHANNELS | ANTIMICROBIAL PEPTIDES | BACTERICIDAL LECTIN | CONFORMATION | PROMOTES | LIPID BILAYER-MEMBRANES | SOLVENT | INNATE IMMUNITY | Peptidoglycan - metabolism | Immunity, Mucosal - immunology | Humans | Intestines - chemistry | Lectins, C-Type - immunology | Porins - metabolism | Crystallography, X-Ray | Gram-Negative Bacteria - metabolism | Listeria monocytogenes - immunology | Antigens, Neoplasm - chemistry | Gram-Negative Bacteria - immunology | Porins - antagonists & inhibitors | Intestines - immunology | Lectins, C-Type - chemistry | Immunity, Mucosal - drug effects | Lectins, C-Type - metabolism | Anti-Bacterial Agents - chemistry | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Listeria monocytogenes - metabolism | Porins - chemistry | Phospholipids - metabolism | Biomarkers, Tumor - antagonists & inhibitors | Symbiosis | Microbial Viability - drug effects | Antigens, Neoplasm - immunology | Models, Molecular | Anti-Bacterial Agents - metabolism | Pancreatitis-Associated Proteins | Cryoelectron Microscopy | Gram-Negative Bacteria - drug effects | Anti-Bacterial Agents - immunology | Intestines - microbiology | Cell Membrane Permeability - drug effects | Lipopolysaccharides - pharmacology | Anti-Bacterial Agents - pharmacology | Biomarkers, Tumor - chemistry | Biomarkers, Tumor - immunology | Lectins, C-Type - antagonists & inhibitors | Listeria monocytogenes - drug effects | Biological research | Physiological aspects | Lectins | Membranes (Biology) | Health aspects | Biology, Experimental | Proteins | Membranes | Pore size | Microscopy | Listeria | Lipids | Index Medicus
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2019, Volume 2003, pp. 201 - 251
Neutron scattering has significant benefits for examining the structure of protein-lipid complexes. Cold (slow) neutrons are nondamaging and predominantly... 
Protein–lipid complexes | Neutron reflectometry | Small-angle neutron scattering | Tethered lipid bilayer membranes | Neutron scattering | SMALPs | Supported lipid bilayers | Deuteration | Bilayer deposition | Isotopic contrast variation | Nanodiscs
Journal Article
Journal of Physical Chemistry Letters, ISSN 1948-7185, 09/2017, Volume 8, Issue 17, pp. 4308 - 4313
The lateral diffusion of embedded proteins along lipid membranes in protein-poor conditions has been successfully described in terms of the Saffman-Delbruck... 
BROWNIAN-MOTION | GIANT UNILAMELLAR VESICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | TRANSLATIONAL DIFFUSION | NANOSCIENCE & NANOTECHNOLOGY | PLASMA-MEMBRANE | SINGLE-MOLECULE TRACKING | FLUID | LIPID-BILAYER MEMBRANES | FORCE-FIELD | DOMAINS | LATERAL DIFFUSION | Index Medicus
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 04/2019, Volume 33, Issue 4, pp. 5755 - 5771
The antibiotic bacitracin (Bac) inhibits cell wall synthesis of gram-positive bacteria. Here, we discovered a totally different activity of Bac: the... 
ANTHRAX LETHAL | CHANNEL FUNCTION | toxin inhibitor | BIOCHEMISTRY & MOLECULAR BIOLOGY | bacterial binary AB-toxins | DIPHTHERIA-TOXIN | LIPID BILAYER-MEMBRANES | CELL BIOLOGY | anthrax toxin | BINDING-KINETICS | PERFRINGENS IOTA-TOXIN | TYROSINE GLYCOSYLATION | BIOLOGY | BOTULINUM C2 TOXIN | ADP-RIBOSYLATION | CLOSTRIDIUM
Journal Article
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