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Cochrane Database of Systematic Reviews, ISSN 1469-493X, 11/2018, Volume 2018, Issue 11, p. CD008170
.... Despite widespread use for hypertension, the efficacy and safety of RAS inhibitors compared to other antihypertensive drug classes remains unclear... 
Hypertension | Kidney disease | Stroke | Renin‐Angiotensin System | Sodium Chloride Symporter Inhibitors | Cause of Death | Angiotensin‐Converting Enzyme Inhibitors | Randomized Controlled Trials as Topic | Calcium Channel Blockers | Myocardial Infarction | Management/treatment of Specific sub‐types of Hypertensive Patients | Management of specific sub‐types of hypertensive patients | Heart Failure | Kidney Failure, Chronic | Antihypertensive Agents | Heart & circulation | Medicine General & Introductory Medical Sciences | Treatment of essential Hypertension | Patients with other cardiovascular risk factors (smoking; diabetes; high serum cholesterol levels; arterial fibrillation) | CALCIUM-CHANNEL BLOCKER | INTIMA-MEDIA THICKNESS | LIPID-LOWERING TREATMENT | DEPENDENT DIABETES-MELLITUS | MEDICINE, GENERAL & INTERNAL | END-POINT REDUCTION | CONVERTING ENZYME-INHIBITION | DOUBLE-BLIND | BLOOD-PRESSURE CONTROL | QUALITY-OF-LIFE | LEFT-VENTRICULAR HYPERTROPHY | Myocardial Infarction - epidemiology | Stroke - prevention & control | Calcium Channel Blockers - adverse effects | Humans | Calcium Channel Blockers - therapeutic use | Hypertension - drug therapy | Sodium Chloride Symporter Inhibitors - adverse effects | Sodium Chloride Symporter Inhibitors - therapeutic use | Antihypertensive Agents - therapeutic use | Antihypertensive Agents - adverse effects | Heart Failure - prevention & control | Stroke - chemically induced | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Kidney Failure, Chronic - epidemiology | Angiotensin-Converting Enzyme Inhibitors - adverse effects | Renin-Angiotensin System - drug effects | Aged | Hypertension - mortality | Heart Failure - chemically induced | Heart Failure - mortality
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2016, Volume 134, Issue 21, pp. e468 - e495
Journal Article
Pharmacological reviews, ISSN 1521-0081, 2013, Volume 65, Issue 2, pp. 578 - 640
Journal Article
Journal Article
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 2012, Volume 52, Issue 1, pp. 198 - 207
Statins, the widely prescribed cholesterol-lowering drugs for the treatment of cardiovascular disease, cause adverse skeletal muscle side effects ranging from fatigue to fatal rhabdomyolysis... 
Oxidative stress | Mitochondria | Hydrogen peroxide | Simvastatin | Mitochondrial respiration | Superoxide | Human skeletal muscle | Apoptosis | COA REDUCTASE INHIBITORS | COENZYME-A REDUCTASE | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | INDUCE APOPTOSIS | MUSCLE-CELLS | STATIN-ASSOCIATED MYOPATHY | PERMEABILITY TRANSITION | LIPID-LOWERING DRUGS | MYOTOXICITY | ENDOCRINOLOGY & METABOLISM | Simvastatin - adverse effects | Gene Expression - drug effects | Oxidative Stress | Apoptosis - drug effects | Humans | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Electron Transport Complex I - metabolism | Oxygen Consumption - physiology | Dose-Response Relationship, Drug | Myoblasts - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Myoblasts - metabolism | Electron Transport Complex I - genetics | Cell Respiration - drug effects | Myoblasts - cytology | Superoxides - metabolism | Muscular Diseases - chemically induced | Respiratory System Agents - pharmacology | Muscular Diseases - metabolism | Mitochondria - metabolism | Muscular Diseases - pathology | Mitochondria - drug effects | Anticholesteremic Agents - adverse effects | Adenosine Diphosphate - pharmacology | Hydrogen Peroxide - metabolism | Signal Transduction - drug effects | Cell Differentiation - drug effects | Oxygen Consumption - drug effects | Muscle Fibers, Skeletal - cytology | Primary Cell Culture | Proto-Oncogene Proteins c-bcl-2 - genetics | Enzymes | Low density lipoproteins | Dimethyl sulfoxide | Dosage and administration | Mitochondrial DNA | Permeability | Glutamate | Cells | Muscles | Drugs | Cell culture | Myotubes | Bcl-2 protein | Fatigue | Oxygen consumption | Nuclei | Skeletal muscle | Myoblasts | Atrophy | Electron transport chain | statins | Cardiovascular diseases | Electron transport | mitochondria | hydrogen peroxide | simvastatin | apoptosis | superoxide | oxidative stress | mitochondrial respiration | human skeletal muscle
Journal Article
Journal Article