Chemical & Pharmaceutical Bulletin, ISSN 0009-2363, 2015, Volume 63, Issue 5, pp. 334 - 340
Liquid crystalline nanoparticles (LCNs) were prepared using glyceryl monooleyl ether (GME) by the modified film rehydration method. Hydrogenated lecithin (HL),...
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2013, Volume 454, Issue 2, pp. 625 - 632
Defining appropriate delivery strategies of therapeutic proteins, based on lipid nanoparticulate carriers, requires knowledge of the nanoscale organization...
Neurotrophin | Protein nanoencapsulation | PEGylated liquid crystalline nanocarriers | BDNF | Hexosomes | PEPTIDE DRUGS | MULTIVESICULAR LIPOSOMES | PARTICLES | X-RAY-DIFFRACTION | WATER CHANNELS | IN-VITRO | PHARMACOLOGY & PHARMACY | CHITOSAN-COATED LIPOSOMES | BICONTINUOUS CUBIC PHASE | DRUG-DELIVERY SYSTEMS | SUSTAINED-RELEASE | Microscopy, Electron, Transmission | Brain-Derived Neurotrophic Factor - chemistry | Lipids - chemistry | Nanoparticles - chemistry | Histones - chemistry | X-Ray Diffraction | Nanoparticles - ultrastructure | Scattering, Small Angle | Chymotrypsinogen - chemistry | Polyethylene Glycols - chemistry
Neurotrophin | Protein nanoencapsulation | PEGylated liquid crystalline nanocarriers | BDNF | Hexosomes | PEPTIDE DRUGS | MULTIVESICULAR LIPOSOMES | PARTICLES | X-RAY-DIFFRACTION | WATER CHANNELS | IN-VITRO | PHARMACOLOGY & PHARMACY | CHITOSAN-COATED LIPOSOMES | BICONTINUOUS CUBIC PHASE | DRUG-DELIVERY SYSTEMS | SUSTAINED-RELEASE | Microscopy, Electron, Transmission | Brain-Derived Neurotrophic Factor - chemistry | Lipids - chemistry | Nanoparticles - chemistry | Histones - chemistry | X-Ray Diffraction | Nanoparticles - ultrastructure | Scattering, Small Angle | Chymotrypsinogen - chemistry | Polyethylene Glycols - chemistry
Journal Article
3.
Toward functional nanocomposites: taking the best of nanoparticles, polymers, and small molecules
Chemical Society reviews, ISSN 0306-0012, 04/2013, Volume 42, Issue 7, pp. 2654 - 2678
Nanocomposites, composed of organic and inorganic building blocks, can combine the properties from the parent constituents and generate new properties to meet...
Nanoparticles | Thin films | Construction | Foundations | Nanocomposites | Nanocomposite materials | Polymers | Block copolymers
Nanoparticles | Thin films | Construction | Foundations | Nanocomposites | Nanocomposite materials | Polymers | Block copolymers
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 03/2019, Volume 58, Issue 10, pp. 2958 - 2978
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized by a polymer based outer corona. Bicontinuous lipid cubic phases...
self-assembly | lipids | nanoparticles | drug delivery | cubosomes | DRUG-DELIVERY | INTERNAL STRUCTURE | ANTIMICROBIAL PEPTIDES | CHEMISTRY, MULTIDISCIPLINARY | GLYCEROL DIOLEATE | IN-VITRO | CUBIC-PHASE | LIQUID-CRYSTALLINE NANOPARTICLES | EX-VIVO | SUSTAINED-RELEASE | CYTOTOXICITY | Drugs | Nanoparticles | Membrane lipids | Drug delivery systems | Ecstasy (Drug) | Vehicles | Channel pores | Aquaporins | Lipids | Drug delivery | Lipid bilayers | Membrane proteins | Proteins | Biomedical materials | Bioreactors | Liposomes | Polymers | Surface area | Biosensors
self-assembly | lipids | nanoparticles | drug delivery | cubosomes | DRUG-DELIVERY | INTERNAL STRUCTURE | ANTIMICROBIAL PEPTIDES | CHEMISTRY, MULTIDISCIPLINARY | GLYCEROL DIOLEATE | IN-VITRO | CUBIC-PHASE | LIQUID-CRYSTALLINE NANOPARTICLES | EX-VIVO | SUSTAINED-RELEASE | CYTOTOXICITY | Drugs | Nanoparticles | Membrane lipids | Drug delivery systems | Ecstasy (Drug) | Vehicles | Channel pores | Aquaporins | Lipids | Drug delivery | Lipid bilayers | Membrane proteins | Proteins | Biomedical materials | Bioreactors | Liposomes | Polymers | Surface area | Biosensors
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 2013, Volume 42, Issue 7, pp. 2654 - 2678
Nanocomposites, composed of organic and inorganic building blocks, can combine the properties from the parent constituents and generate new properties to meet...
SELF-ASSEMBLED STRUCTURES | SEPARATED BLOCK-COPOLYMERS | COIL DIBLOCK COPOLYMERS | SIDE-CHAIN | GOLD NANORODS | COPOLYMER THIN-FILMS | 2 LENGTH SCALES | COMB-SHAPED SUPRAMOLECULES | CHEMISTRY, MULTIDISCIPLINARY | LIQUID-CRYSTALLINE POLYMERS | MAGNETIC-FIELD ALIGNMENT
SELF-ASSEMBLED STRUCTURES | SEPARATED BLOCK-COPOLYMERS | COIL DIBLOCK COPOLYMERS | SIDE-CHAIN | GOLD NANORODS | COPOLYMER THIN-FILMS | 2 LENGTH SCALES | COMB-SHAPED SUPRAMOLECULES | CHEMISTRY, MULTIDISCIPLINARY | LIQUID-CRYSTALLINE POLYMERS | MAGNETIC-FIELD ALIGNMENT
Journal Article
PROGRESS IN CHEMISTRY, ISSN 1005-281X, 12/2014, Volume 26, Issue 12, pp. 1930 - 1941
Silver nanoparticles have been the focus of research in recent decades because of their distinct physical, chemical, and biological properties. The application...
ENHANCED RAMAN-SPECTROSCOPY | ANTIMICROBIAL PROPERTIES | silver polymeric nanocomposites | OPTICAL-PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | LIQUID-CRYSTALLINE POLYMERS | AQUEOUS-SOLUTION | silver nanoparticles | EXCELLENT ANTIBACTERIAL EFFICACY | GREEN SYNTHESIS | shape control synthesis | RAPID SYNTHESIS | IN-SITU | POLYOL SYNTHESIS
ENHANCED RAMAN-SPECTROSCOPY | ANTIMICROBIAL PROPERTIES | silver polymeric nanocomposites | OPTICAL-PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | LIQUID-CRYSTALLINE POLYMERS | AQUEOUS-SOLUTION | silver nanoparticles | EXCELLENT ANTIBACTERIAL EFFICACY | GREEN SYNTHESIS | shape control synthesis | RAPID SYNTHESIS | IN-SITU | POLYOL SYNTHESIS
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 01/2018, Volume 269, pp. 374 - 392
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung cancer therapy. The inhalation route offers many advantages, being...
Nanocomposites | Nanotoxicology | Lung cancer | Pulmonary drug delivery | Nanocarriers | Microparticles | Nanoaggregates | IN-VIVO PHARMACOKINETICS | COLONY-STIMULATING FACTOR | TARGETED PULMONARY DELIVERY | DRY POWDER INHALATION | CHEMISTRY, MULTIDISCIPLINARY | LIPOSOME AEROSOL TREATMENT | LINKED CASEIN NANOPARTICLES | NANOSTRUCTURED LIPID CARRIERS | LIQUID-CRYSTALLINE NANOPARTICLES | PHARMACOLOGY & PHARMACY | SUSTAINED-RELEASE MICROCARRIER | POLYMER HYBRID NANOPARTICLES | Lung Neoplasms - drug therapy | Animals | Nanostructures - administration & dosage | Humans | Administration, Inhalation | Antineoplastic Agents - administration & dosage | Drug Delivery Systems | Drugs | Drug delivery systems | Pharmacy | Health aspects | Nanotechnology | Vehicles | Index Medicus
Nanocomposites | Nanotoxicology | Lung cancer | Pulmonary drug delivery | Nanocarriers | Microparticles | Nanoaggregates | IN-VIVO PHARMACOKINETICS | COLONY-STIMULATING FACTOR | TARGETED PULMONARY DELIVERY | DRY POWDER INHALATION | CHEMISTRY, MULTIDISCIPLINARY | LIPOSOME AEROSOL TREATMENT | LINKED CASEIN NANOPARTICLES | NANOSTRUCTURED LIPID CARRIERS | LIQUID-CRYSTALLINE NANOPARTICLES | PHARMACOLOGY & PHARMACY | SUSTAINED-RELEASE MICROCARRIER | POLYMER HYBRID NANOPARTICLES | Lung Neoplasms - drug therapy | Animals | Nanostructures - administration & dosage | Humans | Administration, Inhalation | Antineoplastic Agents - administration & dosage | Drug Delivery Systems | Drugs | Drug delivery systems | Pharmacy | Health aspects | Nanotechnology | Vehicles | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2010, Volume 132, Issue 8, pp. 2729 - 2742
Water-soluble arene-cored "clicked" and non-"clicked" dendrimers terminated by 27, 81, and 243 triethyleneglycol (TEG) tethers (respectively generations G0,...
AMBIENT CONDITIONS | PD NANOPARTICLES | TRANSITION-METAL-COMPLEXES | DRUG-DELIVERY | SPHERICAL SUPRAMOLECULAR DENDRIMERS | ELECTRON-RESERVOIR COMPLEXES | LIQUID-CRYSTALLINE PHASE | CATALYTIC-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | POLYMERIC PSEUDOCROWN ETHERS | BIMETALLIC NANOPARTICLES | Gold - chemistry | Particle Size | Dendrimers - chemistry | Polyethylene Glycols - chemistry | Nanoparticles - chemistry | Nanoparticles - ultrastructure | Ethylene glycol | Gold | Solvation | Triazoles | Analysis | Organometallic compounds | Oxidation-reduction reaction | Chemical properties | Structure
AMBIENT CONDITIONS | PD NANOPARTICLES | TRANSITION-METAL-COMPLEXES | DRUG-DELIVERY | SPHERICAL SUPRAMOLECULAR DENDRIMERS | ELECTRON-RESERVOIR COMPLEXES | LIQUID-CRYSTALLINE PHASE | CATALYTIC-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | POLYMERIC PSEUDOCROWN ETHERS | BIMETALLIC NANOPARTICLES | Gold - chemistry | Particle Size | Dendrimers - chemistry | Polyethylene Glycols - chemistry | Nanoparticles - chemistry | Nanoparticles - ultrastructure | Ethylene glycol | Gold | Solvation | Triazoles | Analysis | Organometallic compounds | Oxidation-reduction reaction | Chemical properties | Structure
Journal Article
Nanoscale, ISSN 2040-3364, 03/2011, Volume 3, Issue 3, pp. 919 - 924
We demonstrate that oral delivery of self-assembled nanostructured nanoparticles consisting of 5-fluorouracil (5-FU) lipid prodrugs results in a highly...
BUCCAL DELIVERY-SYSTEMS | DISPERSIONS | DESIGN | PHYSICS, APPLIED | LIQUID-CRYSTALLINE | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | BREAST | CAPECITABINE | ORAL FLUOROPYRIMIDINE CARBAMATE | VEHICLES | MONOETHANOLAMIDE LIPIDS | HUMAN LIVER | Prodrugs | Administration, Oral | Drug Compounding - methods | Nanocapsules - administration & dosage | Humans | Treatment Outcome | Antimetabolites, Antineoplastic - chemistry | Breast Neoplasms - drug therapy | Nanocapsules - chemistry | Antimetabolites, Antineoplastic - administration & dosage | Lipids - chemistry | Animals | Fluorouracil - administration & dosage | Breast Neoplasms - pathology | Fluorouracil - chemistry | Nanomedicine - methods | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Crystallization - methods | Nanoparticles | Nanocomposites | Tumours | Lipids | Nanomaterials | Sustained release | Nanostructure | Conversion
BUCCAL DELIVERY-SYSTEMS | DISPERSIONS | DESIGN | PHYSICS, APPLIED | LIQUID-CRYSTALLINE | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | BREAST | CAPECITABINE | ORAL FLUOROPYRIMIDINE CARBAMATE | VEHICLES | MONOETHANOLAMIDE LIPIDS | HUMAN LIVER | Prodrugs | Administration, Oral | Drug Compounding - methods | Nanocapsules - administration & dosage | Humans | Treatment Outcome | Antimetabolites, Antineoplastic - chemistry | Breast Neoplasms - drug therapy | Nanocapsules - chemistry | Antimetabolites, Antineoplastic - administration & dosage | Lipids - chemistry | Animals | Fluorouracil - administration & dosage | Breast Neoplasms - pathology | Fluorouracil - chemistry | Nanomedicine - methods | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Crystallization - methods | Nanoparticles | Nanocomposites | Tumours | Lipids | Nanomaterials | Sustained release | Nanostructure | Conversion
Journal Article
Langmuir, ISSN 0743-7463, 02/2018, Volume 34, Issue 8, pp. 2764 - 2773
Mesophase structures of self-assembled lyotropic liquid crystalline nanoparticles are important factors that directly influence their ability to encapsulate...
SYSTEM | MESOPHASE STRUCTURE | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | OLEIC-ACID | CHEMISTRY, PHYSICAL | WATER CHANNELS | DNA RELEASE | CHEMISTRY, MULTIDISCIPLINARY | AQUEOUS-PHASE BEHAVIOR | LIQUID-CRYSTALLINE NANOPARTICLES | CUBIC PHASE | X-RAY
SYSTEM | MESOPHASE STRUCTURE | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | OLEIC-ACID | CHEMISTRY, PHYSICAL | WATER CHANNELS | DNA RELEASE | CHEMISTRY, MULTIDISCIPLINARY | AQUEOUS-PHASE BEHAVIOR | LIQUID-CRYSTALLINE NANOPARTICLES | CUBIC PHASE | X-RAY
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 1900, Volume 137, Issue 33, pp. 10728 - 10734
Self-assembly of nanoparticles into designed structures with controlled interparticle separations is of crucial importance for the engineering of new materials...
CORED DENDRIMERS | CLICK CHEMISTRY | DNA | STABILITY | LIQUID-CRYSTALLINE NANOPARTICLES | NANOCRYSTALS | OPTICAL-PROPERTIES | INORGANIC NANOPARTICLES | METAL NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | Nanoparticles | Gold | Chemical properties
CORED DENDRIMERS | CLICK CHEMISTRY | DNA | STABILITY | LIQUID-CRYSTALLINE NANOPARTICLES | NANOCRYSTALS | OPTICAL-PROPERTIES | INORGANIC NANOPARTICLES | METAL NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | Nanoparticles | Gold | Chemical properties
Journal Article
ACS Applied Materials & Interfaces, ISSN 1944-8244, 09/2015, Volume 7, Issue 36, pp. 20360 - 20368
Hepatocellular carcinoma is one of the most common cancers in adults and develops due to activation of oncogenes and inactivation of tumor suppressor genes....
multilayer | layer-by-layer | sorafenib | hepatocellular carcinoma | liquid crystalline nanoparticles | SYSTEM | IN-VITRO | PHARMACOKINETICS | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | RELEASE | BIOAVAILABILITY | Niacinamide - analogs & derivatives | Liquid Crystals - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Drug Carriers - toxicity | Male | Phenylurea Compounds - toxicity | Spectroscopy, Fourier Transform Infrared | Drug Carriers - chemistry | Niacinamide - chemistry | Phenylurea Compounds - chemistry | Microscopy, Atomic Force | Erythrocytes - cytology | Liver Neoplasms - pathology | Hemolysis | Cell Survival - drug effects | Microscopy, Electron, Transmission | Rats | Nanoparticles - toxicity | Rats, Sprague-Dawley | Erythrocytes - drug effects | Hep G2 Cells | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Drug Liberation | Calorimetry, Differential Scanning | Niacinamide - toxicity | Polymers - chemistry | Carcinoma, Hepatocellular - metabolism | Hydrogen-Ion Concentration
multilayer | layer-by-layer | sorafenib | hepatocellular carcinoma | liquid crystalline nanoparticles | SYSTEM | IN-VITRO | PHARMACOKINETICS | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | RELEASE | BIOAVAILABILITY | Niacinamide - analogs & derivatives | Liquid Crystals - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Humans | Drug Carriers - toxicity | Male | Phenylurea Compounds - toxicity | Spectroscopy, Fourier Transform Infrared | Drug Carriers - chemistry | Niacinamide - chemistry | Phenylurea Compounds - chemistry | Microscopy, Atomic Force | Erythrocytes - cytology | Liver Neoplasms - pathology | Hemolysis | Cell Survival - drug effects | Microscopy, Electron, Transmission | Rats | Nanoparticles - toxicity | Rats, Sprague-Dawley | Erythrocytes - drug effects | Hep G2 Cells | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Drug Liberation | Calorimetry, Differential Scanning | Niacinamide - toxicity | Polymers - chemistry | Carcinoma, Hepatocellular - metabolism | Hydrogen-Ion Concentration
Journal Article
Soft Matter, ISSN 1744-683X, 2016, Volume 12, Issue 36, pp. 7539 - 7550
Soft mesoporous hierarchically structured particles were created by the self-assembly of an amphiphilic deep cavitand cyclodextrin beta CD-nC(10) (degree of...
CUBIC PHASES | CATIONIC SURFACTANTS | POLYMER SCIENCE | PHYSICS, MULTIDISCIPLINARY | DRUG-DELIVERY | SYNCHROTRON-RADIATION SAXS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | SCATTERING PATTERNS | TARGETED CO-DELIVERY | SURFACE PRESSURE MEASUREMENTS | LIQUID-CRYSTALLINE NANOPARTICLES | LANGMUIR-BLODGETT SYSTEMS | AMPHIPHILIC CYCLODEXTRINS | Carriers | Nanoparticles | Self assembly | Transmission electron microscopy | Cubic lattice | Lipids | Cyclodextrins | Nanostructure | Chemical Sciences
CUBIC PHASES | CATIONIC SURFACTANTS | POLYMER SCIENCE | PHYSICS, MULTIDISCIPLINARY | DRUG-DELIVERY | SYNCHROTRON-RADIATION SAXS | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | SCATTERING PATTERNS | TARGETED CO-DELIVERY | SURFACE PRESSURE MEASUREMENTS | LIQUID-CRYSTALLINE NANOPARTICLES | LANGMUIR-BLODGETT SYSTEMS | AMPHIPHILIC CYCLODEXTRINS | Carriers | Nanoparticles | Self assembly | Transmission electron microscopy | Cubic lattice | Lipids | Cyclodextrins | Nanostructure | Chemical Sciences
Journal Article