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Epileptic Disorders, ISSN 1294-9361, 12/2017, Volume 19, Issue 4, pp. 450 - 455
Aims . Somatic mutation of the lissencephaly‐1 gene is a cause of subcortical band heterotopia (“double cortex”). The severity of the phenotype depends on the... 
LIS1 | Double Cortex | somatic mosaic mutation | gene | subcortical band heterotopia | LIS1 gene
Journal Article
Cell Cycle, ISSN 1538-4101, 01/2017, Volume 16, Issue 1, pp. 7 - 8
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 12/2018, Volume 176, Issue 12, pp. 2808 - 2812
We describe a mother and son with focal epilepsy, mild cognitive impairment, and pachygyria, which was parieto‐occipital in the mother and with remarkable... 
epilepsy | LIS1 | malformations of cortical development | pachygyria | PAFAH1B1 | DOUBLECORTIN | ACETYLHYDROLASE | GENETICS & HEREDITY | LISSENCEPHALY GENE | CHILD | MISSENSE MUTATIONS | Phenotypes | Epilepsy | Cortex | Cognitive ability | LIS1 protein | Mutation | Gene expression
Journal Article
Revue Neurologique, ISSN 0035-3787, 04/2014, Volume 170, pp. A147 - A148
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2019, Volume 10
Single-molecule cytoplasmic dynein function is well understood, but there are major gaps in mechanistic understanding of cellular dynein regulation. We... 
NEURONAL MIGRATION | INSULIN | TRANSPORT | ACTIVATION | COMPLEX | MECHANISM | TUG-OF-WAR | MULTIDISCIPLINARY SCIENCES | LIS1 | GLUT4 | NUDE
Journal Article
Nature Physics, ISSN 1745-2473, 05/2018, Volume 14, Issue 5, pp. 515 - 522
Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges... 
PLURIPOTENT STEM-CELLS | NEURONAL MIGRATION | NEURAL PROGENITORS | PHYSICS, MULTIDISCIPLINARY | RNA-SEQ | GROWTH | LISSENCEPHALY GENE | LIS1 | MODEL | RADIAL GLIA | CEREBRAL-CORTEX | Wrinkling | Brain | Stability | Scaling | Modulus of elasticity | Folding | Physics | Strain
Journal Article
Cell Reports, ISSN 2211-1247, 03/2018, Volume 22, Issue 12, pp. 3277 - 3291
Intracellular transport of membranous organelles and protein complexes to various destinations is fundamental to signaling transduction and cellular function.... 
dynein | LIS1 | endocytosis | development | NDE1 | FGF signaling | CYTOPLASMIC DYNEIN | EARLY EMBRYONIC LETHALITY | LIMB | MITOTIC SPINDLE | LUNG DEVELOPMENT | ENDOCYTOSIS | EXPRESSION | NEURONAL MIGRATION DEFECTS | MOUSE LUNG | LISSENCEPHALY GENE LIS1 | CELL BIOLOGY
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 3/2002, Volume 156, Issue 6, pp. 959 - 968
Mutations in the human LIS1 gene cause type I lissencephaly, a severe brain developmental disease involving gross disorganization of cortical neurons. In lower... 
COS cells | Neurons | Kinetochores | Microtubules | Antibodies | Monoclonal antibodies | Cell biology | Gene expression regulation | Two hybrid system techniques | Cells | LIS1 | Dynactin | CLIP-170 | Dynein | CYTOPLASMIC DYNEIN | PROTEIN | ACTIVATING-FACTOR ACETYLHYDROLASE | ASPERGILLUS-NIDULANS | CHROMOSOME ALIGNMENT | INTERMEDIATE-CHAIN BINDING | MICROTUBULE ORGANIZATION | CELL BIOLOGY | dynein | HEAVY-CHAIN | kinetochores | LISSENCEPHALY GENE-PRODUCT | IN-VIVO | dynactin | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Protein Transport - drug effects | Trinucleotide Repeats - genetics | Molecular Motor Proteins - genetics | Neoplasm Proteins | 1-Alkyl-2-acetylglycerophosphocholine Esterase | Molecular Motor Proteins - metabolism | Peptide Fragments - genetics | Dyneins - metabolism | Peptide Fragments - metabolism | Kinetochores - metabolism | Dynactin Complex | Gene Expression Regulation - physiology | Protein Structure, Tertiary - genetics | Mutation - genetics | Protein Transport - genetics | Gene Expression Regulation - drug effects | Phenotype | Animals | Mitosis - physiology | Fluorescent Antibody Technique | HeLa Cells | COS Cells | Reports | Cell research | Research | lissencephaly | LIS1 gene | CLIP-170 protein | dynein; dynactin; LIS1; CLIP-170; kinetochores
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 12/2009, Volume 10, Issue 12, pp. 854 - 865
Journal Article