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Drug Metabolism and Disposition, ISSN 0090-9556, 12/2011, Volume 39, Issue 12, pp. 2347 - 2354
Raloxifene, a selective estrogen receptor modulator, exhibits quite large interindividual variability in pharmacokinetics and pharmacodynamics. In women,... 
Glucuronosyltransferase - genetics | Raloxifene Hydrochloride - metabolism | Glucuronides - metabolism | Humans | Kidney - enzymology | Genotype | Microsomes, Liver - enzymology | Intestines - enzymology | Polymorphism, Genetic
Journal Article
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 12/2016, Volume 29, Issue 12, pp. 2108 - 2110
Exposure to neurotoxic, chiral PCBs has been associated with neurodevelopmental disorders, but their metabolism in humans remains unexplored. We investigated... 
CHEMISTRY, MEDICINAL | RAT | 2,2',3,3',6,6'-HEXACHLOROBIPHENYL | MICE | TOXICOLOGY | CHEMISTRY, MULTIDISCIPLINARY | DISPOSITION | POLYCHLORINATED-BIPHENYLS | Polychlorinated Biphenyls - metabolism | Hydroxylation | Humans | Microsomes, Liver - metabolism | Rapid Report
Journal Article
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 07/2017, Volume 141, pp. 200 - 209
Journal Article
Molecules, ISSN 1420-3049, 03/2017, Volume 22, Issue 3, p. 443
AM-2201 is a synthetic cannabinoid that acts as a potent agonist at cannabinoid receptors and its abuse has increased. However, there are no reports of the... 
AM-2201 | Human liver microsomes | UDP-glucuronosyltransferase inhibition | Drug-drug interaction | Cytochrome P450 inhibition | human liver microsomes | cytochrome P450 inhibition | MAJOR PHYTOCANNABINOIDS | MARIJUANA SMOKE | GLUCURONIDATION | CHEMISTRY, ORGANIC | RECEPTOR | INDUCERS | IN-VITRO | METABOLISM | UDP-GLUCURONOSYLTRANSFERASE 2B7 | SYNTHETIC CANNABINOIDS | drug-drug interaction | DRUG-DRUG INTERACTIONS | Naphthalenes - chemistry | Isoenzymes | Humans | Cytochrome P-450 Enzyme System - metabolism | Enzyme Activation - drug effects | Naphthalenes - pharmacology | Dose-Response Relationship, Drug | Tandem Mass Spectrometry | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Chromatography, Liquid | Glucuronosyltransferase - antagonists & inhibitors | Inhibitory Concentration 50 | Indoles - pharmacology | Microsomes, Liver - enzymology | Molecular Structure | Indoles - chemistry | Cytochrome | Liver | Diclofenac | Receptors | Enzymatic activity | Drug interaction | Inhibition | CYP2D6 protein | Cannabinoid receptors | Glucuronosyltransferase | Enzymes | Abuse | Hydroxylation | Cytochrome P450 | Drug interactions | Mass spectroscopy | Liquid chromatography | Pharmacology | CYP1A2 protein | Microsomes | Naloxone | Uridine | Amodiaquine | Midazolam | Chenodeoxycholic acid | Mass spectrometry | In vitro methods and tests
Journal Article