Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 2, pp. 466 - 481
One of the defining features of the liver is the capacity to maintain a constant size despite injury. Although the precise molecular signals involved in the...
Gastroenterology and Hepatology | DISEASED MOUSE-LIVER | RAT-LIVER | HEPATOCELLULAR-CARCINOMA | CLONAL IDENTIFICATION | BONE-MARROW | IN-VIVO | HEPATOCYTE TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | EPITHELIAL PROGENITOR CELLS | FETAL LIVER | HEPATIC OVAL CELLS | Prognosis | Prospective Studies | Risk Assessment | Humans | Cell Communication | Liver Failure - pathology | Rats | Graft Survival | Treatment Outcome | Forecasting | Liver Regeneration - physiology | Stem Cell Transplantation - methods | Animals | Liver Failure - therapy | Graft Rejection | Stem Cells - physiology | Mice | Stem Cell Transplantation - trends | Cell Differentiation - physiology | Hepatocytes - physiology | Disease Models, Animal | Stem cell research | Embryonic stem cells | Growth factors | Liver | Hematopoietic stem cells
Gastroenterology and Hepatology | DISEASED MOUSE-LIVER | RAT-LIVER | HEPATOCELLULAR-CARCINOMA | CLONAL IDENTIFICATION | BONE-MARROW | IN-VIVO | HEPATOCYTE TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | EPITHELIAL PROGENITOR CELLS | FETAL LIVER | HEPATIC OVAL CELLS | Prognosis | Prospective Studies | Risk Assessment | Humans | Cell Communication | Liver Failure - pathology | Rats | Graft Survival | Treatment Outcome | Forecasting | Liver Regeneration - physiology | Stem Cell Transplantation - methods | Animals | Liver Failure - therapy | Graft Rejection | Stem Cells - physiology | Mice | Stem Cell Transplantation - trends | Cell Differentiation - physiology | Hepatocytes - physiology | Disease Models, Animal | Stem cell research | Embryonic stem cells | Growth factors | Liver | Hematopoietic stem cells
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2008, Volume 26, Issue 17, pp. 2800 - 2805
In an effort to review the evidence that liver cancer stem cells exist, two fundamental questions must be addressed. First, do hepatocellular carcinomas (HCC)...
PROGENITOR CELLS | HEPATOCYTES | MATURATION ARREST | EPITHELIAL-CELLS | RAT | ONCOLOGY | DIFFERENTIATION THERAPY | GROWTH | STEM/PROGENITOR CELLS | HUMAN HEPATOCELLULAR-CARCINOMA | EXPRESSION | Bile Ducts, Intrahepatic - pathology | Liver Regeneration | Carcinoma, Hepatocellular - physiopathology | Cell Proliferation | Humans | Liver Neoplasms, Experimental - chemically induced | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Liver Neoplasms - pathology | Precancerous Conditions - pathology | Cell Differentiation | Cell Transformation, Neoplastic - pathology | Liver Neoplasms, Experimental - pathology | Hepatoblastoma - pathology | Index Medicus
PROGENITOR CELLS | HEPATOCYTES | MATURATION ARREST | EPITHELIAL-CELLS | RAT | ONCOLOGY | DIFFERENTIATION THERAPY | GROWTH | STEM/PROGENITOR CELLS | HUMAN HEPATOCELLULAR-CARCINOMA | EXPRESSION | Bile Ducts, Intrahepatic - pathology | Liver Regeneration | Carcinoma, Hepatocellular - physiopathology | Cell Proliferation | Humans | Liver Neoplasms, Experimental - chemically induced | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Liver Neoplasms - pathology | Precancerous Conditions - pathology | Cell Differentiation | Cell Transformation, Neoplastic - pathology | Liver Neoplasms, Experimental - pathology | Hepatoblastoma - pathology | Index Medicus
Journal Article
2012, Methods in molecular biology, ISBN 9781617794681, Volume 826., x, 226
Book
1997, Medical intelligence unit (Unnumbered), ISBN 1570594260, 349
Book
Nature Reviews Cancer, ISSN 1474-175X, 01/2012, Volume 12, Issue 1, pp. 23 - 38
After years of extensive scientific discovery much has been learned about the networks that regulate epithelial homeostasis. Loss of expression or functional...
ACTIVATED PROTEIN-KINASE | HIPPO SIGNALING-PATHWAY | ONCOLOGY | MEDIATES CONTACT INHIBITION | INTESTINAL REGENERATION | BETA-CATENIN | C-IOTA | TIGHT JUNCTION | MITOTIC SPINDLE ORIENTATION | ASYMMETRIC DIVISION | TUMOR-SUPPRESSOR PATHWAY | Causes of | Physiological aspects | Research | Epithelial cells | Carcinogenesis | Invasiveness | Liver | Cell adhesion | Stem cells | Cell division | Homeostasis | Polarity | Tumorigenesis | Cancer
ACTIVATED PROTEIN-KINASE | HIPPO SIGNALING-PATHWAY | ONCOLOGY | MEDIATES CONTACT INHIBITION | INTESTINAL REGENERATION | BETA-CATENIN | C-IOTA | TIGHT JUNCTION | MITOTIC SPINDLE ORIENTATION | ASYMMETRIC DIVISION | TUMOR-SUPPRESSOR PATHWAY | Causes of | Physiological aspects | Research | Epithelial cells | Carcinogenesis | Invasiveness | Liver | Cell adhesion | Stem cells | Cell division | Homeostasis | Polarity | Tumorigenesis | Cancer
Journal Article
2019, Methods in Molecular Biology, ISBN 9781493989607, Volume 1905
eBook
Cell Stem Cell, ISSN 1934-5909, 08/2017, Volume 21, Issue 2, pp. 166 - 177
Fibrosis is associated with organ failure and high mortality and is commonly characterized by aberrant myofibroblast accumulation. Investigating the cellular...
organ fibrosis | mesenchymal stem cells | lineage tracing | HEPATIC STELLATE CELLS | SONIC HEDGEHOG | RESIDENT FIBROBLASTS | LIVER FIBROSIS | MULTIPLE ORGANS | GROWTH-FACTOR | CARDIAC FIBROSIS | STROMAL CELLS | PULMONARY-FIBROSIS | BONE-MARROW FIBROSIS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Mesenchymal Stromal Cells - metabolism | Animals | Organ Specificity | Humans | Fibrosis
organ fibrosis | mesenchymal stem cells | lineage tracing | HEPATIC STELLATE CELLS | SONIC HEDGEHOG | RESIDENT FIBROBLASTS | LIVER FIBROSIS | MULTIPLE ORGANS | GROWTH-FACTOR | CARDIAC FIBROSIS | STROMAL CELLS | PULMONARY-FIBROSIS | BONE-MARROW FIBROSIS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Mesenchymal Stromal Cells - metabolism | Animals | Organ Specificity | Humans | Fibrosis
Journal Article
Pediatric Research, ISSN 0031-3998, 01/2018, Volume 83, Issue 1-2, pp. 223 - 231
Recent advances have allowed for three-dimensional (3D) printing technologies to be applied to biocompatible materials, cells and supporting components,...
ENGINEERED HEART-VALVES | BIOINK | ENCAPSULATION | VIABILITY | ALTERNATIVES | PEDIATRICS | DIFFERENTIATION | SCAFFOLDS | TECHNOLOGY | HYDROGEL | STRATEGIES | Human Umbilical Vein Endothelial Cells | Adipose Tissue - physiology | Bone and Bones - physiology | Nervous System | Skin - metabolism | Biocompatible Materials - chemistry | Humans | Mesenchymal Stem Cells - physiology | Muscle, Skeletal - physiology | Wound Healing | Cardiovascular System | Regenerative Medicine - methods | Animals | Bioprinting - methods | Lasers | Liver - physiology | Mice | Induced Pluripotent Stem Cells - cytology | Printing, Three-Dimensional | Artificial Organs
ENGINEERED HEART-VALVES | BIOINK | ENCAPSULATION | VIABILITY | ALTERNATIVES | PEDIATRICS | DIFFERENTIATION | SCAFFOLDS | TECHNOLOGY | HYDROGEL | STRATEGIES | Human Umbilical Vein Endothelial Cells | Adipose Tissue - physiology | Bone and Bones - physiology | Nervous System | Skin - metabolism | Biocompatible Materials - chemistry | Humans | Mesenchymal Stem Cells - physiology | Muscle, Skeletal - physiology | Wound Healing | Cardiovascular System | Regenerative Medicine - methods | Animals | Bioprinting - methods | Lasers | Liver - physiology | Mice | Induced Pluripotent Stem Cells - cytology | Printing, Three-Dimensional | Artificial Organs
Journal Article
Hepatology, ISSN 0270-9139, 01/2009, Volume 49, Issue 1, pp. 318 - 329
Although the existence of cancer stem cells (CSCs) was first proposed over 40 years ago, only in the past decade have these cells been identified in...
BIPOTENTIAL PROGENITOR CELLS | PANCREAS DEVELOPMENT | PROTEIN-KINASE-C | TGF-BETA | EPITHELIAL-CELLS | ALDEHYDE DEHYDROGENASE | MAMMARY STEM/PROGENITOR CELLS | SELF-RENEWAL | HUMAN BREAST-CANCER | BETA-CATENIN | GASTROENTEROLOGY & HEPATOLOGY | Liver Transplantation | Embryonic Stem Cells - cytology | Prognosis | Humans | Biomarkers - analysis | Transforming Growth Factor beta - physiology | Receptors, Notch - physiology | Male | Hedgehog Proteins - physiology | Living Donors | Liver - growth & development | Liver Regeneration - physiology | Cell Lineage | Carcinoma, Hepatocellular - pathology | Neoplastic Stem Cells - pathology | Signal Transduction - physiology | Carcinoma, Hepatocellular - therapy | Liver - cytology | Wnt Proteins - physiology | beta Catenin - physiology | Neoplastic Stem Cells - physiology
BIPOTENTIAL PROGENITOR CELLS | PANCREAS DEVELOPMENT | PROTEIN-KINASE-C | TGF-BETA | EPITHELIAL-CELLS | ALDEHYDE DEHYDROGENASE | MAMMARY STEM/PROGENITOR CELLS | SELF-RENEWAL | HUMAN BREAST-CANCER | BETA-CATENIN | GASTROENTEROLOGY & HEPATOLOGY | Liver Transplantation | Embryonic Stem Cells - cytology | Prognosis | Humans | Biomarkers - analysis | Transforming Growth Factor beta - physiology | Receptors, Notch - physiology | Male | Hedgehog Proteins - physiology | Living Donors | Liver - growth & development | Liver Regeneration - physiology | Cell Lineage | Carcinoma, Hepatocellular - pathology | Neoplastic Stem Cells - pathology | Signal Transduction - physiology | Carcinoma, Hepatocellular - therapy | Liver - cytology | Wnt Proteins - physiology | beta Catenin - physiology | Neoplastic Stem Cells - physiology
Journal Article
Science, ISSN 0036-8075, 11/2008, Volume 322, Issue 5903, pp. 945 - 949
Pluripotent stem cells have been generated from mouse and human somatic cells by viral expression of the transcription factors Oct4, Sox2, Klf4, and c-Myc. A...
Germ cells | Hepatocytes | Genetic vectors | Induced pluripotent stem cells | Somatic cells | Epithelial cells | Cell lines | Stem cells | Fibroblasts | Reports | Liver cells | INDUCTION | EXPRESSION | MULTIDISCIPLINARY SCIENCES | FIBROBLASTS | LIVER | Male | Genes, myc | Hepatocytes - metabolism | Teratoma - etiology | Liver - embryology | Cellular Reprogramming | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Hepatocytes - cytology | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Cloning, Molecular | Adenoviridae - genetics | Female | Cell Differentiation | Transgenes | Fibroblasts - metabolism | Fibroblasts - virology | Cell Line | Pluripotent Stem Cells - cytology | Adenoviridae - physiology | Mice, SCID | Virus Integration | Proto-Oncogene Proteins c-myc - metabolism | Pluripotent Stem Cells - metabolism | Animals | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - transplantation | Hepatocytes - virology | Fibroblasts - cytology | Liver - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Genetic Vectors | Kruppel-Like Transcription Factors - genetics | Chimera | Physiological aspects | Properties | Viruses | Gene expression | Transgenic animals | Rodents | Index Medicus
Germ cells | Hepatocytes | Genetic vectors | Induced pluripotent stem cells | Somatic cells | Epithelial cells | Cell lines | Stem cells | Fibroblasts | Reports | Liver cells | INDUCTION | EXPRESSION | MULTIDISCIPLINARY SCIENCES | FIBROBLASTS | LIVER | Male | Genes, myc | Hepatocytes - metabolism | Teratoma - etiology | Liver - embryology | Cellular Reprogramming | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | Hepatocytes - cytology | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Cloning, Molecular | Adenoviridae - genetics | Female | Cell Differentiation | Transgenes | Fibroblasts - metabolism | Fibroblasts - virology | Cell Line | Pluripotent Stem Cells - cytology | Adenoviridae - physiology | Mice, SCID | Virus Integration | Proto-Oncogene Proteins c-myc - metabolism | Pluripotent Stem Cells - metabolism | Animals | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - transplantation | Hepatocytes - virology | Fibroblasts - cytology | Liver - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Genetic Vectors | Kruppel-Like Transcription Factors - genetics | Chimera | Physiological aspects | Properties | Viruses | Gene expression | Transgenic animals | Rodents | Index Medicus
Journal Article