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Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2011, Volume 11, Issue 4, pp. 334 - 339
Journal Article
Journal of Analytical Toxicology, ISSN 0146-4760, 04/2018, Volume 42, Issue 3, pp. e27 - e32
Abstract Novel psychoactive substances (NPS), and specifically novel opioids, continue to cause adverse events, including death, within drug-using populations.... 
CHEMISTRY, ANALYTICAL | TOXICOLOGY | HUMAN LIVER-MICROSOMES | METABOLISM | FENTANYL | SYNTHETIC OPIOIDS
Journal Article
Pharmacopsychiatry, ISSN 0176-3679, 01/2018, Volume 51, Issue 1/02, pp. 9 - 62
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2018, Volume 61, Issue 14, pp. 5822 - 5880
The electronic properties and relatively small size of fluorine endow it with considerable versatility as a bioisostere and it has found application as a... 
PEPTIDASE-IV INHIBITOR | CHEMISTRY, MEDICINAL | MECHANISM-BASED INHIBITION | HUMAN CATHEPSIN-L | KINASE BTK INHIBITOR | SMALL-MOLECULE INHIBITORS | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | PROTEIN KSP INHIBITORS | HUMAN LIVER-MICROSOMES | GENERATION DOPAMINERGIC AGENTS | ORTHOGONAL MULTIPOLAR INTERACTIONS
Journal Article
by Dai, ZR and Ning, J and Sun, GB and Wang, P and Zhang, F and Ma, HP and Zou, LW and Hou, J and Wu, JJ and Ge, GB and Sun, XB and Yang, L
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 02/2019, Volume 10, p. 52
Bufotalin (BFT), one of the naturally occurring bufodienolides, has multiple pharmacological and toxicological effects including antitumor activity and... 
VITRO | BUFALIN | hydroxylation | ACTIVE-SITE | cytochrome P450 3A (CYP3A) | PHASE-I METABOLISM | docking simulations | human liver microsomes (HLMs) | HUMAN LIVER-MICROSOMES | DRUG-DRUG INTERACTION | CYTOTOXIC BUFADIENOLIDES | bufotalin | ISOFORM-SPECIFIC PROBE | PHARMACOLOGY & PHARMACY | BINDING
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 11/2018, Volume 367, Issue 2, pp. 322 - 334
High-permeability-low-molecular-weight acids/zwitterions [i.e., extended clearance classification system class 1A (ECCS 1A) drugs] are considered to be cleared... 
VITRO | COA REDUCTASE INHIBITORS | HUMAN HEPATOCYTES | IN-VIVO EXTRAPOLATION | INTERINDIVIDUAL VARIABILITY | QUANTITATIVE PREDICTION | PHARMACOKINETIC PARAMETERS | PHARMACOLOGY & PHARMACY | METABOLIC-CLEARANCE | HUMAN LIVER-MICROSOMES | DISPOSITION
Journal Article
Current Drug Metabolism, ISSN 1389-2002, 2014, Volume 15, Issue 1, pp. 48 - 61
Journal Article
Journal Article