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LANCET INFECTIOUS DISEASES, ISSN 1473-3099, 07/2014, Volume 14, Issue 7, pp. 572 - 580
Background Daily oral triple therapy is effective at halting HIV disease progression, but can have toxic effects and is costly. We investigated whether dual... 
INFECTIOUS DISEASES | RALTEGRAVIR | EFFICACY | SAFETY | ANALOGS | EFAVIRENZ | LOPINAVIR/RITONAVIR | DARUNAVIR/RITONAVIR | DOLUTEGRAVIR | SPARING REGIMEN | TENOFOVIR/EMTRICITABINE
Journal Article
IDCases, ISSN 2214-2509, 11/2019, p. e00643
Journal Article
AIDS, ISSN 0269-9370, 2015, Volume 29, Issue 18, pp. 2447 - 2457
Objective: To evaluate whether once daily (q.d.) lopinavir/ritonavir is noninferior to twice daily (b.i.d.) dosing in children. Design: International,... 
HIV-1 | Randomized | Trial | Children | Lopinavir/ritonavir | Once daily
Journal Article
AIDS, ISSN 0269-9370, 11/2011, Volume 25, Issue 17, pp. 2113 - 2122
Objective: To explore darunavir/ritonavir (DRV/r) plus raltegravir (RAL) combination therapy in antiretroviral-naive patients. Design: Phase IIb, single-arm,... 
INFECTIOUS DISEASES | SAFETY | antiretroviral therapy | nucleoside sparing | raltegravir | INITIAL TREATMENT | IMMUNOLOGY | COMBINATION | VIROLOGY | HIV-1 VIRAL LOAD | ANTIRETROVIRAL DRUG-RESISTANCE | darunavir | LOPINAVIR/RITONAVIR | INFECTION | ONCE-DAILY DARUNAVIR/RITONAVIR | TENOFOVIR
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 07/2019, Volume 74, Issue 7, pp. 1992 - 2002
Abstract Background Rilpivirine is widely prescribed in people living with HIV. Although trough plasma concentrations have been associated with virological... 
INFECTIOUS DISEASES | EFFICACY | SAFETY | REVERSE-TRANSCRIPTASE | ADULTS | MICROBIOLOGY | COMPARTMENTS | PHASE-3 | HIV DYNAMICS | PHARMACOKINETICS | EFAVIRENZ | PHARMACOLOGY & PHARMACY | LOPINAVIR/RITONAVIR
Journal Article
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, ISSN 0305-7453, 08/2018, Volume 73, Issue 8, pp. 2120 - 2128
Background: In the ANRS 165 DARULIGHT study (NCT02384967) carried out in HIV-infected patients, the use of a darunavir/ritonavir-containing regimen with a... 
TRIAL | INFECTIOUS DISEASES | DARUNAVIR | TREATMENT-NAIVE | PLASMA | EFFICACY | SAFETY | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | LOPINAVIR/RITONAVIR | TENOFOVIR | RITONAVIR
Journal Article
Drug Discovery Today, ISSN 1359-6446, 01/2019, Volume 24, Issue 1, pp. 263 - 271
Malaria is threatening a resurgence because of drug resistance against frontline artemisinin-based combination therapies (ACTs). This necessitates the... 
EARLY-PREGNANCY | SAFETY | MATERNAL USE | RESISTANCE | PROTON PUMP INHIBITORS | RISK | PHARMACOLOGY & PHARMACY | 1ST TRIMESTER | LOPINAVIR/RITONAVIR | AZITHROMYCIN | EXPOSURE
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9987, pp. 2606 - 2615
Summary Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to high plasma tenofovir concentrations. Tenofovir alafenamide... 
Internal Medicine | KIDNEY-DISEASE | RATES | MEDICINE, GENERAL & INTERNAL | ABACAVIR-LAMIVUDINE | BONE-MINERAL DENSITY | SAFETY | ADULTS | ANTIRETROVIRAL THERAPY | LOPINAVIR/RITONAVIR | COUNT | EXPOSURE | Humans | Male | Thiazoles - administration & dosage | Carbamates - administration & dosage | Arthralgia - chemically induced | Thiazoles - adverse effects | Sleep Initiation and Maintenance Disorders - chemically induced | Tenofovir | Adenine - adverse effects | Quinolones - adverse effects | Adult | Anti-HIV Agents - therapeutic use | Deoxycytidine - adverse effects | Female | Headache - chemically induced | Emtricitabine | Adenine - analogs & derivatives | Kidney - drug effects | Respiration Disorders - chemically induced | Double-Blind Method | Anti-HIV Agents - adverse effects | Deoxycytidine - administration & dosage | HIV Infections - virology | Organophosphonates - adverse effects | Treatment Outcome | CD4 Lymphocyte Count | Nausea | Adenine - administration & dosage | Organophosphonates - administration & dosage | Bone Density - drug effects | Quinolones - administration & dosage | Carbamates - adverse effects | HIV Infections - drug therapy | Viral Load - drug effects | Cobicistat | Deoxycytidine - analogs & derivatives | Drug Combinations | Medical colleges | Clinical trials | Cross infection | Nosocomial infections | HIV (Viruses) | Drug therapy | Health aspects | HIV infection | Analysis | Antiretroviral drugs | Infections | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV
Journal Article
Journal Article
by Gianotti, N and Lorenzini, P and Cozzi-Lepri, A and De Luca, A and Madeddu, G and Sighinolfi, L and Pinnetti, C and Santoro, C and Meraviglia, P and Mussini, C and Antinori, A and Monforte, AD and Andreoni, M and Angarano, G and Castelli, F and Cauda, R and Di Perri, G and Galli, M and Iardino, R and Ippolito, G and Lazzarin, A and Perno, CF and von Schloesser, F and Viale, P and Castagna, A and Ceccherini-Silberstein, F and Girardi, E and Lo Caputo, S and Puoti, M and Ammassari, A and Balotta, C and Bandera, A and Bonfanti, P and Bonora, S and Borderi, M and Calcagno, A and Calza, L and Capobianchi, MR and Cingolani, A and Cinque, P and Di Biagio, A and Gori, A and Guaraldi, G and Lapadula, G and Lichtner, M and Maggiolo, F and Marchetti, G and Marcotullio, S and Monno, L and Nozza, S and Roldan, EQ and Rossotti, R and Rusconi, S and Santoro, MM and Saracino, A and Zaccarelli, M and Fanti, I and Galli, L and Rodano, A and Shanyinde, M and Tavelli, A and Carletti, F and Carrara, S and Di Caro, A and Graziano, S and Petrone, F and Prota, G and Quartu, S and Truffa, S and Giacometti, A and Costantini, A and Valeriani, C and Suardi, C and Donati, V and Verucchi, G and Minardi, C and Quirino, T and Abeli, C and Manconi, PE and Piano, P and Cacopardo, B and Celesia, B and Vecchiet, J and Falasca, K and Segala, D and Mazzotta, F and Vichi, F and Cassola, G and Viscoli, C and Alessandrini, A and Bobbio, N and Mazzarello, G and Mastroianni, C and Belvisi, V and Caramma, I and Chiodera, A and Castelli, AP and Rizzardini, G and Ridolfo, AL and Piolini, R and ... and ICONA Fdn Study Grp
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, ISSN 0305-7453, 09/2019, Volume 74, Issue 9, pp. 2732 - 2741
Objectives: Our aim was to investigate the durability of different initial regimens in patients starting ART with CD4+ counts <200 cells/mm(3) and HIV-RNA >5... 
INFECTIOUS DISEASES | EFFICACY | RALTEGRAVIR | ADULTS | MICROBIOLOGY | DOLUTEGRAVIR | DRUG-RESISTANCE | INDIVIDUALS | TENOFOVIR-EMTRICITABINE | NAIVE PATIENTS | PHARMACOLOGY & PHARMACY | LOPINAVIR/RITONAVIR | INHIBITOR
Journal Article
The Journal of antimicrobial chemotherapy, ISSN 0305-7453, 06/2019, Volume 74, Issue 6, pp. 1679 - 1692
Objectives: To assess, at ART initiation, the impact of baseline substitutions in protease, Gag and gp41 regions on the virological response to a first-line... 
DIMERIZATION INHIBITION | INFECTIOUS DISEASES | NAIVE HIV-1-INFECTED PATIENTS | CROSS-RESISTANCE | MICROBIOLOGY | DRUG-RESISTANCE | POLYMORPHISM | MUTANTS | AMPRENAVIR | SUBSTRATE | IMMUNODEFICIENCY-VIRUS TYPE-1 | PHARMACOLOGY & PHARMACY | LOPINAVIR/RITONAVIR
Journal Article
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 04/2011, Volume 154, Issue 7, p. 445
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 18, pp. 1726 - 1737
In this randomized, controlled trial in Africa and India, combination antiretroviral therapy was more effective than standard therapy in preventing... 
PRETERM DELIVERY | CHILD-MORTALITY | MEDICINE, GENERAL & INTERNAL | TENOFOVIR DISOPROXIL FUMARATE | INFECTED WOMEN | PROGESTERONE LEVELS | ADVERSE BIRTH OUTCOMES | LOPINAVIR/RITONAVIR | LOPINAVIR EXPOSURE | PROTEASE | PREGNANCY | HIV Infections - prevention & control | Infant Mortality | Humans | African Americans | Perinatal Care | Infant | Young Adult | Adult | Female | HIV Infections - transmission | Drug Therapy, Combination | Infant, Newborn | Infant, Low Birth Weight | Anti-Retroviral Agents - therapeutic use | Tenofovir - therapeutic use | Zidovudine - adverse effects | Anti-Retroviral Agents - adverse effects | CD4 Lymphocyte Count | Gestational Age | Pregnancy | Infant, Premature | Zidovudine - therapeutic use | HIV Infections - ethnology | Nevirapine - administration & dosage | Infectious Disease Transmission, Vertical - prevention & control | Pregnancy Outcome | Prevention | Highly active antiretroviral therapy | Complications and side effects | Care and treatment | Nevirapine | Pregnant women | HIV patients | Dosage and administration | Research | HIV (Viruses) | Zidovudine | Health aspects | Emtricitabine | Neonates | Antiretroviral drugs | Breastfeeding & lactation | Ritonavir | Lopinavir | Lamivudine | Infants | Gestation | Antiretroviral therapy | Postpartum | CD4 antigen | Disease prevention | Tenofovir | Cost-benefit analysis | Disease transmission | Maternal & child health | Human immunodeficiency virus--HIV | Birth weight | Drug therapy
Journal Article