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FEBS Letters, ISSN 0014-5793, 08/2018, Volume 592, Issue 15, pp. 2612 - 2623
The crosstalk between the free fatty acid receptor FFA4 and the lysophosphatidic acid receptor LPA1 seems to be of pathophysiological importance. We explored... 
FFA4 receptor | receptor crosstalk | FRET | LPA1 desensitization | receptor–receptor interaction
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 10/2018, Volume 1863, Issue 10, pp. 1237 - 1245
Microglia regulate immune responses in the brain, and their activation is key to the pathogenesis of diverse neurological diseases. Receptor-mediated... 
TACE | ERK1/2 | TNF-α | Septic brain | LPA1 | Microglia | LPA | TNF-alpha | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | KINASE | NECROSIS-FACTOR-ALPHA | RELEASE | CELL BIOLOGY | BIOPHYSICS | LYSOPHOSPHOLIPIDS | GENE-EXPRESSION | LIPOPOLYSACCHARIDE | CHANNELS | POLARIZATION | CELL-LINE
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 05/2019, Volume 110, pp. 91 - 102
Lysophosphatidic acid (LPA) is a ubiquitous lysophospholipid that induces a wide range of cellular processes such as wound healing, differentiation,... 
Nucleus | LPA | PKCα | LPA1 receptor | Glioblastoma
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 08/2018, Volume 833, pp. 8 - 15
The Lysophosphatidic Acid 1 Receptor (LPA receptor) has been linked to the initiation and progression of a variety of poorly treated fibrotic conditions.... 
Backscattering interferometry | G-protein signalling | Negative allosteric modulator | LPA1 receptor | Fibrosis | receptor | LPA
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 12/2018, Volume 841, pp. 49 - 56
Lysophosphatidic acid receptor 1 (LPA ) is one of six G protein-coupled receptors (GPCRs) activated by the bioactive lipid, lysophosphatidic acid (LPA).... 
GPCR | Carrageenan | Phospholipase A2 (PLA2) | Lysophosphatidic acid (LPA) | Inflammatory pain | LPA1 | PLA | LPA | Phospholipase A
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2019, Volume 155, pp. 150 - 161
Lysophosphatidic acid (LPA) is a bioactive lipid mediator of inflammation that binds to its specific cell surface G protein coupled receptors (LPA1-6). It is... 
Depression | Neuronal apoptosis | ROCK2 | RhoA | LPA1 | RHO-FAMILY GTPASES | BEHAVIOR | CELL APOPTOSIS | MODEL | NEUROSCIENCES | LYSOPHOSPHATIDIC ACID | PATHWAY | INFLAMMATION | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION | G proteins | Neurons | Depression, Mental | Apoptosis
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2017, Volume 815, pp. 258 - 265
Lysophosphatidic acid (LPA) modulates the function of many organs, including the lung. A549 is a lung carcinoma-derived cell line, frequently used as a model... 
Calcium signaling | Lysophosphatidic acid receptors | Desensitization | A549 cells | ERK 1/2 phosphorylation | LPA1 | LPA
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 06/2015, Volume 95, Issue 4, pp. 311 - 323
Different lines of evidence indicate that the lysophosphatidic acid (LPA) receptor LPA is involved in neurogenesis, synaptic plasticity and anxiety-related... 
Insulin-like growth factor-I receptor | ERK1/2 | CHO-K1 fibroblasts | Antidepressants | LPA1 receptor | receptor | LPA
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 03/2019, Volume 847, pp. 83 - 90
Current pharmacotherapies for voiding dysfunctions are in need of improvement. Lysophosphatidic acid (LPA) is a phospholipid that contracts the urethra by... 
Lysophosphatidic acid | Urethra | Lower urinary tract symptoms | Nitric oxide | LPA1 | Urine voiding | LPA | MICTURITION REFLEX | NEURAL-CONTROL | TRACT SYMPTOMS SECONDARY | GENE | L-ARGININE | IN-VIVO | MEN | PHARMACOLOGY & PHARMACY | INDUCED RELAXATION | INHIBITOR | Arginine | Drug discovery
Journal Article
Journal Article
Leukemia Research, ISSN 0145-2126, 03/2018, Volume 66, pp. 39 - 48
A common mechanism for inhibition of leukemia cell myeloid differentiation and breast cancer cell motility involving NM23 and EDG2. The gene is overexpressed... 
Cell motility | NM23 | ATRA | EDG2/lpa1 | Myeloid differentiation
Journal Article
Kidney international, ISSN 0085-2538, 3/2017, Volume 91, Issue 3, pp. 628 - 641
The expansion of the fibroblast pool is a critical step in organ fibrosis, but the mechanisms driving expansion remain to be fully clarified. We previously... 
fibroblast | Fibrosis | LPA1 | CTGF
Journal Article
Bone, ISSN 8756-3282, 2011, Volume 49, Issue 3, pp. 395 - 403
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 07/2016, Volume 55, Issue 1, pp. 105 - 116
Journal Article