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PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e104467
In the Materials and Methods section, under the subheading “Animal Care and Usage”, the protocol number approved by the Institutional Animal Care and Use... 
LRP5 protein
Journal Article
Hormone Research in Paediatrics, ISSN 1663-2818, 04/2012, Volume 77, Issue 2, pp. 115 - 120
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2014, Volume 29, Issue 10, pp. 2250 - 2261
Journal Article
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, ISSN 1871-4021, 07/2019, Volume 13, Issue 4, pp. 2381 - 2385
The main of this study was to investigate the association between the rs566442 (V1119V) coding polymorphism of Low-density lipoprotein receptor-related protein... 
LRP5 | Obesity | Postmenopausal women | rs566442
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 02/2017, Volume 56, Issue 2, pp. 191 - 201
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2018, Volume 293, Issue 51, pp. 19710 - 19724
Upon binding to the canonical WNT glycoproteins, Frizzled family receptors (FZDs) and low-density lipoprotein receptor-related protein 5/6 (LRP5/6) undergo a... 
Wnt signaling | SFRP2 | signalosome | hepatoma | cell signaling | cancer | tumor development | Frizzled | LRP5/6 | receptor endocytosis | ACTIVATION | DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LRP5 | DRIVEN | LRP6 | BINDS | INHIBITION | WNT | SELECTIVITY | Index Medicus
Journal Article
Bone, ISSN 8756-3282, 2016, Volume 90, pp. 127 - 132
Abstract Osteogenesis Imperfecta (OI) comprises a group of genetic skeletal fragility disorders. The mildest form of OI, Osteogenesis Imperfecta type I, is... 
Orthopedics | Wnt signaling | Osteogenesis Imperfecta | Mov13 | Lrp5
Journal Article
Human mutation, ISSN 1059-7794, 3/2018, Volume 39, Issue 3, pp. 378 - 382
Expanded mutation detection and novel gene discovery for isolated polycystic liver disease (PCLD) are necessary as 50% of cases do not have identified... 
GANAB | minigene | LRP5 | polycystic liver disease | splice assay
Journal Article
Nature Communications, ISSN 2041-1723, 05/2016, Volume 7, Issue 1, pp. 11505 - 11505
Inhibition of the Wnt antagonist sclerostin increases bone mass in patients with osteoporosis and in preclinical animal models. Here we show increased levels... 
MULTIPLE-MYELOMA | MINERAL DENSITY | INHIBITION | SOST GENE | MULTIDISCIPLINARY SCIENCES | LRP5 MUTATIONS | POSTMENOPAUSAL WOMEN | BETA-CATENIN | WNT | EXPRESSION | BINDING | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 07/2006, Volume 20, Issue 14, pp. 1933 - 1945
Journal Article
American Journal of Reproductive Immunology, ISSN 1046-7408, 06/2018, Volume 80, Issue S1, pp. 77 - 77
Journal Article
NATURE REVIEWS GENETICS, ISSN 1471-0056, 08/2012, Volume 13, Issue 8, pp. 576 - 588
Osteoporosis is among the most common and costly diseases and is increasing in prevalence owing to the ageing of our global population. Clinically defined... 
QUANTITATIVE TRAIT LOCI | LRP5 GENE | METAANALYSIS | BONE-MINERAL DENSITY | GENETICS & HEREDITY | VERTEBRAL FRACTURE | GROWTH-PLATE | PAGETS-DISEASE | POSTMENOPAUSAL WOMEN | FRACTURE RISK | MISSENSE MUTATIONS
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 1, pp. 103 - 110
Recently, the emerging role of microRNAs (miRNAs) has been identified in osteogenesis and the development of osteoporosis. Here, we found that miR-545-3p was... 
LRP5 | SP1 | miR-545-3p | Osteogenesis | Wnt/beta-catenin | Osteoporosis | Genetic transcription | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 04/2018, Volume 28, Issue 6, pp. 1116 - 1121
BMD4503-2 containing a quinoxaline moiety recovered the downregulated activity of the Wnt/β-catenin signaling pathway by competitive binidng to the... 
Virtual screening | Osteoporosis | Wnt/β-catenin signalling pathway | Structure-activity relationships | LRP5/6-sclerostin interaction | SCLEROSTIN | CHEMISTRY, MEDICINAL | DISEASE | CHEMISTRY, ORGANIC | Wnt/beta-catenin signalling pathway | LRP5/6 | Medical colleges | Research institutes | Index Medicus
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 03/2019, Volume 120, Issue 3, pp. 3362 - 3366
Journal Article
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 11/2018, Volume 256, Issue 11, pp. 2149 - 2156
To describe and analyse the clinical and genetic characteristics of digenic familial exudative vitreoretinopathy (FEVR).The study cohort consisted of patients... 
Phenotype | Digenic FEVR | Ophthalmology | FEVR | Medicine & Public Health | Gene | VARIANTS | FZD4 | LRP5 | OPHTHALMOLOGY | MUTATIONS | SPECTRUM | IDENTIFICATION | Medicine, Experimental | Medical research | Anopheles | Genetic aspects | Analysis | Familial exudative vitreoretinopathy | Phenotypes | Genetic analysis | LRP5 protein | Mutation | Age | Genotypes | Index Medicus
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 08/2009, Volume 5, Issue 8, pp. 442 - 447
Osteoblasts and adipocytes differentiate from a common pluripotent precursor, the mesenchymal stem cell (MSC). studies have identified numerous transcription... 
NUCLEAR RECEPTOR SUPERFAMILY | GENE-EXPRESSION | CBFA1 | DIFFERENTIATION | RHEUMATOLOGY | BETA-CATENIN | BONE MASS | TRANSCRIPTION FACTOR | MESENCHYMAL STEM-CELLS | MARROW STROMAL CELLS | PROTEIN-5 LRP5
Journal Article
Toxicologic pathology, ISSN 0192-6233, 10/2017, Volume 45, Issue 7, pp. 864 - 868
The WNT signaling pathway is involved in cellular and tissue functions that control such diverse processes as body axis patterning, cellular proliferation,... 
HBM | bone anabolics | Sost | Wnt | osteoporosis | sclerostin | Lrp5
Journal Article
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