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by Collisson, EA and Campbell, JD and Brooks, AN and Berger, AH and Lee, W and Chmielecki, J and Beer, DG and Cope, L and Creighton, CJ and Danilova, L and Ding, L and Getz, G and Hammerman, PS and Hayes, DN and Hernandez, B and Herman, JG and Heymach, JV and Jurisica, I and Kucherlapati, R and Kwiatkowski, D and Ladanyi, M and Robertson, G and Schultz, N and Shen, RL and Sinha, R and Sougnez, C and Tsao, MS and Travis, WD and Weinstein, JN and Wigle, DA and Wilkerson, MD and Chu, AD and Cherniack, AD and Hadjipanayis, A and Rosenberg, M and Weisenberger, DJ and Laird, PW and Radenbaugh, A and Ma, SG and Stuart, JM and Byers, LA and Baylin, SB and Govindan, R and Meyerson, M and Gabriel, SB and Cibulskis, K and Kim, J and Stewart, C and Lichtenstein, L and Lander, ES and Lawrence, MS and Getz and Kandoth, C and Fulton, R and Fulton, LL and McLellan, MD and Wilson, RK and Ye, K and Fronick, CC and Maher, CA and Miller, CA and Wendl, MC and Cabanski, C and Mardis, E and Wheeler, D and Balasundaram, M and Butterfield, YSN and Carlsen, R and Chuah, E and Dhalla, N and Guin, R and Hirst, C and Lee, D and Li, HYI and Mayo, M and Moore, RA and Mungall, AJ and Schein, JE and Sipahimalani, P and Tam, A and Varhol, R and Robertson, AG and Wye, N and Thiessen, N and Holt, RA and Jones, SJM and Marra, MA and Imielinski, M and Onofrio, RC and Hodis, E and Zack, T and Helman, E and Pedamallu, CS and Mesirov, J and Saksena, G and Schumacher, SE and Carter, SL and Garraway, L and Beroukhim, R and Lee, S and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
NATURE, ISSN 0028-0836, 07/2014, Volume 511, Issue 7511, pp. 543 - 550
Journal Article
Mayo Clinic Proceedings, ISSN 0025-6196, 08/2018, Volume 93, Issue 8, pp. 1153 - 1154
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2009, Volume 361, Issue 10, pp. 947 - 957
This trial compared gefitinib, an inhibitor of the tyrosine kinase of epidermal growth factor (EGFR), with carboplatin plus paclitaxel as initial treatment of... 
CELL LUNG-CANCER | RECEPTOR GENE-MUTATIONS | MEDICINE, GENERAL & INTERNAL | THERAPY | FUNCTIONAL ASSESSMENT | PROSPECTIVE PHASE-II | 1ST-LINE GEFITINIB | EGFR MUTATIONS | TREATED PATIENTS | NEVER-SMOKERS | ERLOTINIB | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Lung Neoplasms - mortality | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antineoplastic Agents - therapeutic use | Carboplatin - adverse effects | Carboplatin - therapeutic use | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Lung Neoplasms - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | Paclitaxel - adverse effects | Adenocarcinoma - drug therapy | Paclitaxel - therapeutic use | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Quinazolines - adverse effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Adenocarcinoma - mortality | Care and treatment | Dosage and administration | Nonsmokers | Gefitinib | Health aspects | Lung cancer | Chemotherapy | Pharmaceutical industry | Ovarian cancer | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 12/2016, Volume 107, Issue 12, pp. 1800 - 1805
We proposed to compare the outcomes of first‐line epidermal growth factor receptor–tyrosine kinase inhibitor (EGFR‐TKI) alone with EGFR‐TKI plus whole‐brain... 
EGFR mutation | radiotherapy | prognosis | Brain metastasis | lung adenocarcinoma | CANCER PATIENTS | GEFITINIB | PHASE-II | RADIATION-THERAPY | TKI | ONCOLOGY | MUTATIONS | ERLOTINIB | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Lung Neoplasms - mortality | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Protein Kinase Inhibitors - adverse effects | Brain Neoplasms - secondary | Adult | Female | Adenocarcinoma - genetics | Retrospective Studies | Brain Neoplasms - mortality | Lung Neoplasms - genetics | ErbB Receptors - antagonists & inhibitors | Proportional Hazards Models | Treatment Outcome | Combined Modality Therapy | Disease Progression | Protein Kinase Inhibitors - administration & dosage | Protein Kinase Inhibitors - therapeutic use | Brain Neoplasms - therapy | Radiotherapy - methods | Aged | Mutation | Neoplasm Staging | Adenocarcinoma - mortality | Adenocarcinoma | Tyrosine | Brain | Medical research | Care and treatment | Epidermal growth factor | Lung cancer | Brain tumors | Medicine, Experimental | Phenols | Metastasis | Radiotherapy | Medical imaging | Epidermal growth factor receptors | Brain cancer | Oncology | Nervous system | Radiation therapy | Cancer therapies | Survival | Patients | Disease control | Metastases | Studies | Survival analysis | Neurotoxicity | Clonal deletion | Medical prognosis | Response rates | Protein-tyrosine kinase | Original
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