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Journal Article
American Journal of Pathology, ISSN 0002-9440, 09/2007, Volume 171, Issue 3, pp. 728 - 738
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7501, pp. 492 - 496
The BRAF kinase is mutated, typically Val 600 -> Glu (V600E), to induce an active oncogenic state in a large fraction of melanomas, thyroid cancers, hairy cell... 
ACTIVATION | MELANOMA | MEK INHIBITION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RAS ONCOGENESIS | CATALYZED OXIDATION REACTIONS | MUTATIONS | CANCER | BETA-ADRENERGIC RECEPTOR | MASS-SPECTROMETRY | Lung Neoplasms - drug therapy | Mitogen-Activated Protein Kinase Kinases - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Mitogen-Activated Protein Kinase Kinases - metabolism | Copper - metabolism | Cation Transport Proteins - genetics | Female | Hepatolenticular Degeneration - drug therapy | Indoles - pharmacology | Phosphorylation - drug effects | Cation Transport Proteins - deficiency | Chelating Agents - therapeutic use | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Lung Neoplasms - genetics | Copper - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Chelating Agents - pharmacology | Drug Repositioning | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Proto-Oncogene Proteins B-raf - genetics | Survival Analysis | Cell Line, Tumor | Mice | Cell Transformation, Neoplastic - drug effects | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Copper in the body | Cellular signal transduction | Growth | Health aspects | Cancer cells | Proteins | Signal transduction | Phosphorylation | Diet | Melanoma | Tumorigenesis | Mutation | Kinases | Tumors
Journal Article
BBA - Reviews on Cancer, ISSN 0304-419X, 12/2009, Volume 1796, Issue 2, pp. 91 - 98
Malignant tumor cells display uncontrolled proliferation, loss of epithelial cell polarity, altered interactions with neighboring cells and the surrounding... 
Rho GTPases | DIRECTED MIGRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | BREAST-CANCER | LUNG-CANCER | HEPATOCELLULAR-CARCINOMA | BIOPHYSICS | ONCOLOGY | IN-VIVO | SQUAMOUS-CELL CARCINOMA | RAS TRANSFORMATION | ABERRANT SOMATIC HYPERMUTATION | CYCLE PROGRESSION | Proteins | Analysis | Genetically modified organisms | Development and progression | Mice | G proteins | Tumors
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2015, Volume 17, Issue 1, pp. 81 - 94
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2014, Volume 19, Issue 5, pp. 795 - 809
Journal Article
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 1, pp. 33 - 38