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life sciences & biomedicine (20) 20
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liver x receptors (11) 11
lxrα (11) 11
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22hc, 22 (1) 1
28-hb-lxr interactions (1) 1
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3 (1) 1
3′utr, 3-prime untranslated region (1) 1
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1. Full Text Liver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α
by Chen, Kai-Ting and Pernelle, Kelig and Tsai, Yuan-Hau and Wu, Yu-Hsuan and Hsieh, Jui-Yu and Liao, Ko-Hsun and Guguen-Guillouzo, Christiane and Wang, Hsei-Wei
Journal of hepatology, ISSN 0168-8278, 2014, Volume 61, Issue 6, pp. 1276 - 1286
Gastroenterology and Hepatology | Hepatogenesis | HepaRG progenitor cell | LXRα/NR1H3 | HNF4A | LXRa/NR1H3 | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Cell Line | Humans | Carbon Tetrachloride - adverse effects | Cell Transplantation | Stem Cells - cytology | Hepatocyte Nuclear Factor 4 - physiology | Mice, SCID | Liver Regeneration - physiology | Hepatocytes - cytology | Animals | Liver Failure - therapy | Liver Failure - chemically induced | Liver X Receptors | Orphan Nuclear Receptors - physiology | Mice, Inbred NOD | Stem Cells - physiology | Mice | In Vitro Techniques | Cell Differentiation - physiology | Hepatocytes - physiology | Disease Models, Animal | Index Medicus | Life Sciences
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2. Full Text Bile acid transporters and regulatory nuclear receptors in the liver and beyond
by Halilbasic, Emina and Claudel, Thierry and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
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3. Full Text Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis
by Yao, Wu and Yang, Peiyan and Qi, Yuanmeng and Jin, Luheng and Zhao, Ahui and Ding, Mingcui and Wang, Di and Li, YiPing and Hao, Changfu
The Science of the total environment, ISSN 0048-9697, 12/2020, Volume 747, pp. 141531 - 141531
LXRα | Silica particles | Pulmonary fibroblasts | Silicosis | Fibrosis | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Index Medicus
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4. Full Text Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice
by González-Granillo, M and Steffensen, K R and Granados, O and Torres, N and Korach-André, M and Ortíz, V and Aguilar-Salinas, C and Jakobsson, T and Díaz-Villaseñor, A and Loza-Valdes, A and Hernandez-Pando, R and Gustafsson, J.-Å and Tovar, A R
Diabetologia, ISSN 0012-186X, 9/2012, Volume 55, Issue 9, pp. 2469 - 2478
Human Physiology | Liver | Metabolic Diseases | LXRα | Internal Medicine | Cholesterol | LXRβ | Soy protein | Medicine & Public Health | Intestine | AMPK | Insulin resistance | Mice | Isoflavones | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Liver - metabolism | Gene Expression Regulation | Insulin Resistance | Bile Acids and Salts - metabolism | Isoflavones - metabolism | Male | Mice, Transgenic | Intestines - metabolism | Hepatocytes - metabolism | Orphan Nuclear Receptors - metabolism | Soybean Proteins - pharmacology | Animals | Protein Isoforms - metabolism | Biological Transport | Diet, High-Fat | Liver X Receptors | Lipid Metabolism - drug effects | Orphan Nuclear Receptors - drug effects | Hepatocytes - drug effects | Physiological aspects | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Lack of association between LXRα and LXRβ gene polymorphisms and prevalence of metabolic syndrome: A case–control study of an Iranian population
by Rooki, Hassan and Ghayour-Mobarhan, Manjid and Haerian, Monir-sadat and Ebrahimi, Mahmoud and Azimzadeh, Pedram and Heidari-Bakavoli, Alireza and Mirfakhraei, Reza and Tavallaie, Shima and Mirhafez, Reza and Ferns, Gordon and Zali, Mohammad-Reza
Gene, ISSN 0378-1119, 12/2013, Volume 532, Issue 2, pp. 288 - 293
LXRα | Single nucleotide polymorphism | Metabolic syndrome | LXRβ | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Haplotypes | Prevalence | Genetic Association Studies | Gene Frequency | Humans | Middle Aged | Male | Orphan Nuclear Receptors - genetics | Case-Control Studies | Linkage Disequilibrium | Metabolic Syndrome - genetics | Liver X Receptors | Adult | Female | Polymorphism, Single Nucleotide | Iran - epidemiology | Metabolic Syndrome - epidemiology | Index Medicus
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6. Full Text Goat liver X receptor α, molecular cloning, functional characterization and regulating fatty acid synthesis in epithelial cells of goat mammary glands
by Wang, Wei and Luo, Jun and Zhong, Yu and Lin, Xian-Zi and Shi, Heng-Bo and Zhu, Jiang-Jiang and Li, Jun and Sun, Yu-Ting and Zhao, Wang-Sheng
Gene, ISSN 0378-1119, 08/2012, Volume 505, Issue 1, pp. 114 - 120
LXRα | Fat acid synthesis | Gene regulation | T0901317 | Dairy goat | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Open Reading Frames - physiology | Fatty Acid Synthases - metabolism | Humans | DNA, Complementary - genetics | Orphan Nuclear Receptors - metabolism | Cattle | Fatty Acids - genetics | Goats - genetics | Isoelectric Point | Liver X Receptors | Cloning, Molecular | Female | Response Elements - physiology | Fatty Acid Synthases - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Organ Specificity - physiology | Protein Structure, Tertiary | Rats | Orphan Nuclear Receptors - genetics | Mammary Glands, Animal - cytology | Goats - metabolism | Sequence Alignment | Animals | Mammary Glands, Animal - metabolism | Sterol Regulatory Element Binding Protein 1 - genetics | Mice | Fatty Acids - biosynthesis | Index Medicus
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7. Full Text The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis
by Kurowska-Stolarska, Mariola, PhD and Hasoo, Manhl K., PhD and Welsh, David J., PhD and Stewart, Lynn, BSc and McIntyre, Donna, PhD and Morton, Brian E., BSc and Johnstone, Steven, PhD and Miller, Ashley M., PhD and Asquith, Darren L., PhD and Millar, Neal L., MD, PhD and Millar, Ann B., MD and Feghali-Bostwick, Carol A., PhD and Hirani, Nikhil, MBChB, PhD and Crick, Peter J., PhD and Wang, Yuqin, PhD and Griffiths, William J., PhD and McInnes, Iain B., MD, PhD and McSharry, Charles, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2016, Volume 139, Issue 6, pp. 1946 - 1956
Allergy and Immunology | fibroblasts | liver X receptor | MicroRNA-155 | alternatively activated macrophages | lung fibrosis | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Cell Count | Humans | Cells, Cultured | Liver X Receptors - metabolism | Pulmonary Fibrosis - genetics | Mice, Knockout | Collagen - metabolism | Macrophages - metabolism | Animals | Bleomycin | Pulmonary Fibrosis - chemically induced | Bronchoalveolar Lavage Fluid - cytology | Lung - metabolism | MicroRNAs - genetics | Pulmonary Fibrosis - metabolism | Liver X Receptors - genetics | Fibroblasts - metabolism | Medical research | Epigenetic inheritance | Medical colleges | Pulmonary fibrosis | MicroRNA | Therapeutics | Medicine, Experimental | Respiratory tract diseases | Research institutes | Homeopathy | Materia medica and therapeutics | Deregulation | Pathogenesis | Liver | Genomics | Macrophages | Assaying | Cell activation | Pathways | Fibroblasts | miRNA | Inhibition | Deposition | Liver X receptors | Lung diseases | Inflammation | Histology | Gene expression | Ribonucleic acid--RNA | Inhibitors | MicroRNAs | Collagen | Fibrosis | Epigenetics | Mice | Index Medicus | Abridged Index Medicus | Arg2, Arginase 2 | Col, Collagen | 22(S)HC, 22(S)-hydroxycholesterol | WT, Wild-type | miR-155, MicroRNA-155 | IPF, Idiopathic pulmonary fibrosis | 3′UTR, 3-Prime untranslated region | LXRα, Liver X receptor alpha | Mechanisms of Allergy and Clinical Immunology
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8. Full Text Time-dependent alterations in mRNA, protein and microRNA during in vitro adipogenesis
by Krishna, Mahesh S and Aneesh Kumar, A and Abdul Jaleel, K A
Molecular and cellular biochemistry, ISSN 0300-8177, 11/2018, Volume 448, Issue 1, pp. 1 - 8
Life Sciences | Biochemistry, general | Mmu-mir-1a-3p | MicroRNA | SRC | LXRα | Medical Biochemistry | Oncology | Cardiology | PPARγ | Adipogenesis | Mmu-mir-23a-3p | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proteins | Obesity | Glucose metabolism | Messenger RNA | Genes | Glucose | Gene expression | Fatty acids | Dextrose | Flow cytometry | Nucleic acids | Metabolism | Nuclear receptors | Ribonucleic acid--RNA | Biological activity | Complexity | Time dependence | Receptors | Molecular modelling | MicroRNAs | miRNA | Aberration | Bioinformatics | Index Medicus
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