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Gut, ISSN 0017-5749, 04/2009, Volume 58, Issue 4, pp. 520 - 529
Background:The antitumoral immune response is one determinant of colorectal cancer (CRC) outcome. Recent work suggests that Foxp3+CD25+CD4+ regulatory T cells... 
PLASMACYTOID DENDRITIC CELLS | REGULATORY-CELLS | SURVIVAL | FOXP3 EXPRESSION | GROWTH-FACTOR-BETA | TGF-BETA | IN-VIVO | DIFFERENTIATION | INTERLEUKIN-6 | GASTROENTEROLOGY & HEPATOLOGY | OVARIAN-CARCINOMA | T-Lymphocyte Subsets - immunology | Adenocarcinoma - pathology | Cell Proliferation | Humans | Middle Aged | Male | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Immune Tolerance - immunology | Aged, 80 and over | Adult | Female | Cytokines - immunology | Neoplasm Invasiveness | Adenocarcinoma - immunology | Immunophenotyping | Colorectal Neoplasms - immunology | Forkhead Transcription Factors - analysis | Lymphocyte Count | Neoplasm Proteins - analysis | Aged | Colorectal Neoplasms - pathology | Neoplasm Staging | Cytokines - biosynthesis | Lymphocytes, Tumor-Infiltrating - immunology | Care and treatment | Immune response | Lymphocytes | Colorectal cancer | Physiological aspects | Development and progression | Research | Proteins | Antigens | Cytokines | Medical prognosis | Software | Experiments | Tumors | Cell adhesion & migration | Adenocarcinoma | Life Sciences | Lymphocytes, Tumor-Infiltrating | Immunology | Neoplasm Proteins | Immunotherapy | T-Lymphocytes, Regulatory | Colorectal Neoplasms | CD4-Positive T-Lymphocytes | T-Lymphocyte Subsets | Lymphocyte Activation | Immune Tolerance | Forkhead Transcription Factors
Journal Article
1990, Current topics in membranes and transport, ISBN 9780121533359, Volume 35., xviii, 628
Book
1982, ISBN 9788716091161, Volume 63., 209
Book
Science, ISSN 0036-8075, 3/2009, Volume 323, Issue 5920, pp. 1488 - 1492
Most of the immunoglobulin A (IgA) in the gut is generated by B cells in the germinal centers of Peyer's patches through a process that requires the presence... 
T lymphocytes | Spleen | Molecules | Peyers patches | Cytokines | B lymphocytes | Plasma cells | AIDS | Reports | Mice | Small intestine | GERMINAL CENTER FORMATION | CXC CHEMOKINE RECEPTOR-5 | POPULATION | ACTIVATION | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | RETINOIC-ACID | DIFFERENTIATION | INTERLEUKIN-21 | LAMINA PROPRIA | EXPRESSION | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Spleen - immunology | T-Lymphocyte Subsets - cytology | Dendritic Cells - immunology | Germinal Center - immunology | Gene Expression Profiling | Adoptive Transfer | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | CD40 Antigens - metabolism | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | T-Lymphocytes, Regulatory - cytology | Cell Differentiation | Intestine, Small - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Lymphocyte Activation | CD4-Positive T-Lymphocytes - cytology | Down-Regulation | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Spleen - cytology | Lymph Nodes - immunology | Forkhead Transcription Factors - genetics | Lymph Nodes - cytology | Peyer's Patches - cytology | Animals | B-Lymphocytes - immunology | Intestine, Small - cytology | T-Lymphocyte Subsets - metabolism | Dendritic Cells - cytology | Immunoglobulin A, Secretory - biosynthesis | Peyer's Patches - immunology | Lymphatic system | Immunology | Cellular biology | Gene expression | Rodents
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 4/2014, Volume 63, Issue 4, pp. 395 - 406
The programmed death-1 (PD-1) molecule is mainly expressed on functionally “exhausted” CD8+ T cells, dampening the host antitumor immune response. We evaluated... 
Immunology | Medicine & Public Health | Oncology | Cancer Research | Breast cancer | Immune evasion | Regulatory T cells | Cancer immunotherapy | PD-1 | APOPTOSIS | PROGNOSIS | TUMOR | RISK | ANTIBODY | IMMUNOLOGY | CHEMOTHERAPY | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | IMMUNOTHERAPY | CD8(+) T-LYMPHOCYTES | B7-H1 | Carcinoma, Lobular - pathology | Follow-Up Studies | Breast Neoplasms - immunology | Humans | Middle Aged | Programmed Cell Death 1 Receptor - analysis | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Antigens, Differentiation, T-Lymphocyte - analysis | Aged, 80 and over | Carcinoma, Ductal, Breast - pathology | Lymphocytes, Tumor-Infiltrating - chemistry | T-Lymphocytes, Regulatory - chemistry | Carcinoma, Lobular - immunology | CD8-Positive T-Lymphocytes - chemistry | Combined Modality Therapy | Carcinoma, Lobular - radiotherapy | T-Lymphocyte Subsets - pathology | Carcinoma, Ductal, Breast - radiotherapy | Forkhead Transcription Factors - analysis | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | T-Lymphocyte Subsets - immunology | Breast Neoplasms - surgery | CD8-Positive T-Lymphocytes - pathology | Prognosis | Carcinoma, Ductal, Breast - immunology | Carcinoma, Ductal, Breast - mortality | Carcinoma, Lobular - mortality | T-Lymphocytes, Cytotoxic - pathology | T-Lymphocyte Subsets - chemistry | Mastectomy | Adult | Female | Radiotherapy, Adjuvant | T-Lymphocytes, Cytotoxic - immunology | Carcinoma, Ductal, Breast - surgery | Carcinoma, Lobular - surgery | Kaplan-Meier Estimate | Disease-Free Survival | Breast Neoplasms - radiotherapy | T-Lymphocytes, Cytotoxic - chemistry | Apoptosis - immunology | Lymphocytes, Tumor-Infiltrating - pathology | Breast Neoplasms - pathology | Lymphocyte Count | Breast Neoplasms - mortality | Aged
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2013, Volume 160, Issue 2, pp. 123 - 132
Summary Gamma delta (γδ) Τ cells are non‐conventional T lymphocyte effectors that can interact with and eradicate tumour cells. Several data demonstrate that... 
gamma delta T lymphocytes | cancer | immunotherapy | monoclonal antibodies | haematological oncology | Haematological oncology | Monoclonal antibodies | Immunotherapy | Gamma delta T lymphocytes | Cancer | T-Lymphocyte Subsets - immunology | Adjuvants, Immunologic - pharmacology | Dendritic Cells - immunology | Humans | Receptors, Antigen, T-Cell, alpha-beta - analysis | Cells, Cultured - transplantation | Receptors, Antigen, T-Cell, gamma-delta - genetics | Gene Rearrangement, delta-Chain T-Cell Antigen Receptor | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | T-Lymphocytes, Cytotoxic - transplantation | T-Lymphocyte Subsets - chemistry | Diphosphonates - therapeutic use | Killer Cells, Natural - immunology | Cells, Cultured - immunology | Tumor Escape - immunology | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Cells, Cultured - drug effects | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Translational Medical Research | Clinical Trials as Topic | Immunity, Innate | T-Lymphocyte Subsets - transplantation | Immunologic Surveillance - immunology | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | T-Lymphocytes, Cytotoxic - chemistry | Receptors, Antigen, T-Cell, gamma-delta - analysis | Neoplasms - immunology | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells - transplantation | Diphosphonates - pharmacology | Immunologic Surveillance | Tumor Escape | Killer Cells, Natural | Dendritic Cells | T-Lymphocytes, Cytotoxic | Neoplasms | CD8-Positive T-Lymphocytes | Life Sciences | Immunology | Mesenchymal Stromal Cells | Receptors, Antigen, T-Cell, alpha-beta | T-Lymphocytes, Regulatory | T-Lymphocyte Subsets | Antigens, Neoplasm | Adjuvants, Immunologic | Cells, Cultured | Diphosphonates | Receptors, Antigen, T-Cell, gamma-delta
Journal Article
Journal Article
Science, ISSN 0036-8075, 5/2011, Volume 332, Issue 6030, pp. 687 - 696
Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell "mass cytometry" to examine healthy human... 
T lymphocytes | Cytometry | Phosphorylation | RESEARCH ARTICLE | B lymphocytes | Stem cells | Cell lines | Bone marrow | Bone marrow cells | Cells | Hematopoietic stem cells | STEM-CELLS | ACTIVATION | LYMPHOCYTE | MULTIDISCIPLINARY SCIENCES | MYELOGENOUS LEUKEMIA | TYROSINE KINASE INHIBITOR | FLOW-CYTOMETRY | DASATINIB | IDENTIFICATION | QUANTITATIVE-ANALYSIS | SIGNALING NETWORKS | Lanthanoid Series Elements | Leukocytes, Mononuclear - metabolism | Flow Cytometry - methods | Humans | Antibodies | Lymphocyte Subsets - immunology | Lymphocyte Subsets - metabolism | T-Lymphocytes - metabolism | Hematopoiesis | Single-Cell Analysis - methods | T-Lymphocytes - drug effects | Bone Marrow Cells - immunology | Leukocytes, Mononuclear - immunology | Mass Spectrometry | Bone Marrow Cells - drug effects | B-Lymphocytes - metabolism | Dasatinib | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Bone Marrow Cells - cytology | Lymphocyte Activation | Lymphocyte Subsets - drug effects | Immunophenotyping | Pyrimidines - pharmacology | Transition Elements | B-Lymphocytes - drug effects | Algorithms | B-Lymphocytes - immunology | Signal Transduction - drug effects | T-Lymphocytes - immunology | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Antigens, Surface - analysis | Bone Marrow Cells - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Evaluation | Flow cytometry | Immune response | Research | Immunopharmacology | Methods
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 20254
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to... 
MESSENGER-RNAS | CANCER-PATIENTS | EXTRACELLULAR VESICLES | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | MICROVESICLES | DIAGNOSTIC BIOMARKERS | INDUCE APOPTOSIS | OVARIAN-CANCER | MODULATION | LYMPHOCYTES | Exosomes - metabolism | Neoplasms - metabolism | CD8-Positive T-Lymphocytes - cytology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Humans | Culture Media, Conditioned - pharmacology | RNA, Messenger - metabolism | Antigens, CD - metabolism | Lectins, C-Type - metabolism | T-Lymphocyte Subsets - drug effects | T-Lymphocytes, Regulatory - cytology | CD8-Positive T-Lymphocytes - metabolism | Real-Time Polymerase Chain Reaction | Microscopy, Electron, Transmission | CD4-Positive T-Lymphocytes - cytology | Apyrase - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Down-Regulation - drug effects | Up-Regulation - drug effects | T-Lymphocytes, Regulatory - drug effects | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | Adenosine - metabolism | Neoplasms - pathology | CD4-Positive T-Lymphocytes - drug effects | Microscopy, Fluorescence | Adenosine | Dendritic cells | CD8 antigen | Gene regulation | Data processing | T cell receptors | Lymphocytes T | Gene expression | Exosomes | Cell surface | CD4 antigen | Polymerase chain reaction | CD69 antigen | Cell activation | Lymphocytes | Down-regulation | Peripheral blood
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2016, Volume 46, Issue 7, pp. 1770 - 1782
We previously demonstrated an accumulation of tumor‐reactive CD4+CD8+ double positive (DP) T cells within melanoma‐infiltrating lymphocytes, supporting their... 
IL‐9R | IL‐9 | CD4+CD8+ double‐positive T lymphocyte | TIL | Melanoma | CD4 | IL-9R | CD8 | double-positive T lymphocyte | IL-9 | TH9 CELLS | CD8(+) | INDUCED APOPTOSIS | INTERLEUKIN-9 | RECEPTOR | PERIPHERAL-BLOOD | IMMUNOLOGY | CYTOKINE EXPRESSION | IN-VIVO | CD4(+) CD8(+) double-positive T lymphocyte | GROWTH-FACTOR | LYMPHOCYTES | T-Lymphocyte Subsets - immunology | Apoptosis - drug effects | Humans | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - immunology | Interleukin-9 - pharmacology | Melanoma - genetics | T-Lymphocyte Subsets - drug effects | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Cytotoxicity, Immunologic - drug effects | Melanoma - metabolism | Receptors, Interleukin-9 - metabolism | Gene Expression | Cytokines - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Lymphocytes, Tumor-Infiltrating - drug effects | Melanoma - pathology | Cell Survival - immunology | Apoptosis - immunology | Receptors, Interleukin-9 - genetics | Lymphocyte Activation - drug effects | Melanoma - immunology | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - drug effects | CD8-Positive T-Lymphocytes - immunology | Interleukin-9 - immunology | CD4-Positive T-Lymphocytes - drug effects | Lymphocytes, Tumor-Infiltrating - immunology | Parrots | T cells | Tumors | Life Sciences | Cancer
Journal Article