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Immunity (Cambridge, Mass.), ISSN 1074-7613, 2017, Volume 47, Issue 6, pp. 1129 - 1141.e5
During chronic stimulation, CD8+ T cells acquire an exhausted phenotype characterized by expression of inhibitory receptors, down-modulation of effector... 
differentiation | memory | transcription | exhaustion | BATF | NFAT | NFAT_AP-1_IRF4 composite element | NAICE | metabolic function | chronic infection | IRF4 | CD8 | TCF1 | RESPONSES | ACTIVATION | REGULATORY ELEMENT | MITOCHONDRIA | EXPANSION | DRIVER | INHIBITORY RECEPTOR PD-1 | CHECKPOINT | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Lymphocytic choriomeningitis virus - immunology | Hepatocyte Nuclear Factor 1-alpha - immunology | Hepatocyte Nuclear Factor 1-alpha - genetics | Humans | Basic-Leucine Zipper Transcription Factors - immunology | Lymphocyte Depletion | Interferon Regulatory Factors - deficiency | Lymphocytic Choriomeningitis - immunology | NFATC Transcription Factors - immunology | HEK293 Cells | Receptors, Antigen, T-Cell - immunology | Cell Differentiation | Lymphocytic Choriomeningitis - genetics | Lymphocytic Choriomeningitis - virology | Signal Transduction | Lymphocyte Activation | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Basic-Leucine Zipper Transcription Factors - genetics | Mice, Knockout | Interferon Regulatory Factors - immunology | Lymphocytic choriomeningitis virus - growth & development | Animals | CD8-Positive T-Lymphocytes - virology | Immunologic Memory | Mice | Receptors, Antigen, T-Cell - genetics | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - genetics | NFATC Transcription Factors - genetics | Regulators | Transcription factors | PD-1 protein | CD8 antigen | Genes | Memory | Chronic infection | Viruses | Infections | Lymphocytes T | T-cell receptor | Signal transduction | Receptors | Lymphocytes | Tumor necrosis factor-TNF | Hepatocyte nuclear factor 1 | Antigens | Immunological memory | Memory cells | Tumor cells | T cell receptors | Metabolism | Cell differentiation | Cells | Interferon regulatory factor 4 | Exhaustion | Receptor mechanisms | Metabolic disorders | Viral infections
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Journal of allergy and clinical immunology, ISSN 0091-6749, 2013, Volume 131, Issue 4, pp. 959 - 971
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The Journal of immunology (1950), ISSN 1550-6606, 2008, Volume 181, Issue 7, pp. 4733 - 4741
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