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2017, Methods in molecular biology, ISBN 1493965468, Volume 1514
Web Resource
2017, Methods in molecular biology, ISBN 1493965468, Volume 1514
Web Resource
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 2090 - 2108
Activation of mTOR-dependent pathways regulates the specification and differentiation of CD4(+) T effector cell subsets. Herein, we show that mTOR complex 1... 
MAMMALIAN TARGET | EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-CONTROL | ACTIVATION | TUBEROUS SCLEROSIS COMPLEX | MEMORY DEVELOPMENT | GENE-PRODUCTS | TUMOR-SUPPRESSOR TSC1 | TRANSCRIPTION FACTOR | CUTTING EDGE | Recombinant Fusion Proteins - immunology | Ovalbumin - immunology | CD8-Positive T-Lymphocytes - transplantation | Male | Multiprotein Complexes - genetics | Ras Homolog Enriched in Brain Protein | Glycolysis - drug effects | TOR Serine-Threonine Kinases - deficiency | CD4-CD8 Ratio | TOR Serine-Threonine Kinases - genetics | Lymphopoiesis - physiology | Peptide Fragments - immunology | CD8-Positive T-Lymphocytes - metabolism | TOR Serine-Threonine Kinases - physiology | Thymoma - therapy | Multiprotein Complexes - deficiency | Proto-Oncogene Proteins c-akt - metabolism | Transduction, Genetic | Lymphocyte Activation | Thymoma - immunology | Melanoma, Experimental - therapy | Monomeric GTP-Binding Proteins - deficiency | Multiprotein Complexes - physiology | Cell Line, Tumor | Mice | Mice, Congenic | Protein Processing, Post-Translational | CD8-Positive T-Lymphocytes - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Adoptive Transfer | Mechanistic Target of Rapamycin Complex 2 | Mechanistic Target of Rapamycin Complex 1 | Deoxyglucose - therapeutic use | Melanoma, Experimental - immunology | Deoxyglucose - pharmacology | Female | Neuropeptides - genetics | Genes, Reporter | Rapamycin-Insensitive Companion of mTOR Protein | Neuropeptides - deficiency | Sirolimus - therapeutic use | Mice, Inbred C57BL | Monomeric GTP-Binding Proteins - genetics | Sirolimus - pharmacology | Carrier Proteins - genetics | Animals | Immunologic Memory | Interferon-gamma - biosynthesis | Metabolism | Oncology | Immunology
Journal Article
Immunity, ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 374 - 387
Journal Article
Immunity, ISSN 1074-7613, 02/2015, Volume 42, Issue 2, pp. 252 - 264
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 406 - 414
We report that oral infection with Yersinia pseudotuberculosis results in the development of two distinct populations of pathogen-specific CD8(+)... 
MIGRATION | ORAL INFECTION | DENDRITIC CELLS | MEMORY | PESTIS INFECTION | CHEMOKINE RECEPTOR CXCR3 | YERSINIA-PSEUDOTUBERCULOSIS | GENERATION | IMMUNOLOGY | EFFECTOR-CELLS | ANTIGEN | Yersinia pseudotuberculosis Infections - immunology | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Dendritic Cells - immunology | Dendritic Cells - pathology | CD4-Positive T-Lymphocytes - pathology | Antigens, CD - genetics | CD4-Positive T-Lymphocytes - immunology | Intestinal Mucosa - immunology | Integrin alpha Chains - immunology | Macrophages - immunology | Macrophages - microbiology | Integrin alpha Chains - deficiency | Transforming Growth Factor beta - immunology | Yersinia pseudotuberculosis - immunology | Yersinia pseudotuberculosis Infections - genetics | CD4-Positive T-Lymphocytes - microbiology | CD8-Positive T-Lymphocytes - microbiology | Macrophages - pathology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Cellular Microenvironment | Immunophenotyping | Intestinal Mucosa - microbiology | Mice, Knockout | Animals | Transforming Growth Factor beta - genetics | Yersinia pseudotuberculosis Infections - microbiology | Receptors, CXCR3 - genetics | Receptors, CXCR3 - immunology | Dendritic Cells - microbiology | Immunologic Memory | Mice | Yersinia pseudotuberculosis Infections - pathology | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Cell Movement | Intestinal Mucosa - pathology
Journal Article