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lysobacter enzymogenes (48) 48
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polycyclic tetramate macrolactams (9) 9
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Organic Letters, ISSN 1523-7060, 06/2018, Volume 20, Issue 12, pp. 3504 - 3508
Polycyclic tetramate macrolactams (PoTeMs) are a growing class of natural products with distinct structure and diverse biological activities. By promoter... 
CHEMISTRY, ORGANIC | LYSOBACTER-ENZYMOGENES | IKARUGAMYCIN | ACTIVATION | CYCLIZATION | MARINE SPONGE
Journal Article
Chemical Science, ISSN 2041-6520, 2017, Volume 8, Issue 2, pp. 1607 - 1612
Polycyclic tetramate macrolactams (PTMs) are a growing class of natural products and are derived from a hybrid polyketide synthase (PKS)/non-ribosomal peptide... 
HSAF | XIAMYCIN | LYSOBACTER-ENZYMOGENES C3 | BUTREMYCIN | (+)-IKARUGAMYCIN | IDENTIFICATION | ENANTIOSELECTIVE TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | MARINE SPONGE | IKARUGAMYCIN BIOSYNTHESIS | CYLINDRAMIDE
Journal Article
Chemical Science, ISSN 2041-6520, 01/2017, Volume 8, Issue 2, pp. 1607 - 1612
Polycyclic tetramate macrolactams (PTMs) are a growing class of natural products and are derived from a hybrid polyketide synthase (PKS)/non-ribosomal peptide... 
Peptides | Genes | Cascades | Clusters | Bacteria | Activation | Formations | Gene expression
Journal Article
Chemical Communications, ISSN 1359-7345, 03/2015, Volume 51, Issue 25, pp. 5334 - 5336
Polycyclic tetramate macrolactams (PTMs) are a structurally, bio-medically and biosynthetically intriguing class of bacterial metabolites. By combining parts... 
HSAF | LYSOBACTER-ENZYMOGENES C3 | POLYKETIDE SYNTHASE | BIOSYNTHESIS | COLI | STRAIN | CHEMISTRY, MULTIDISCIPLINARY | Enzymes | Bacteria | Pathways | Metabolites | Machinery | Conversion
Journal Article
RSC Adv, ISSN 2046-2069, 2014, Volume 4, Issue 92, pp. 50566 - 50593
Natural products containing the tetramic acid core scaffold have been isolated from an assortment of terrestrial and marine species and often display wide... 
Journal Article
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 92, pp. 50566 - 50593
Natural products containing the tetramic acid core scaffold have been isolated from an assortment of terrestrial and marine species and often display wide... 
SPONGE MELOPHLUS-SARASSINORUM | MARINE-DERIVED FUNGI | BIOSYNTHETIC GENE-CLUSTER | LYSOBACTER-ENZYMOGENES C3 | MALTOPHILIA STRAIN C3 | RNA-POLYMERASE INHIBITOR | ASYMMETRIC TOTAL-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | C-ACYL REARRANGEMENT | FUNGUS PHOLIOTA-SQUARROSA | STREPTOMYCES SP 17944
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 12/2018, Volume 9, p. 2984
Heat-Stable Antifungal Factor (HSAF) and its analogs are antifungal natural products produced by the biocontrol agent Lysobacter enzymogenes. The production of... 
HSAF | Arginase | Arginine decarboxylase | Lysobacter enzymogenes | S-adenosylmethionine decarboxylase | Spermidine | spermidine | ACID | MICROBIOLOGY | arginine decarboxylase | IDENTIFICATION | arginase | BIOLOGICAL-CONTROL AGENT | POLYAMINES | GROWTH | METABOLITE
Journal Article
by Wang, CT and Xu, H and Zhang, Y and Wu, SZ and Chen, DD and Qian, GL and Hu, BS and Fan, JQ
FEMS MICROBIOLOGY LETTERS, ISSN 0378-1097, 09/2019, Volume 366, Issue 17
Heat-stable antifungal factor (HSAF), which was first isolated from Lysobacter enzymogenes, exhibits inhibitory activities against a wide range of pathogens;... 
NUTRITIONAL-REQUIREMENTS | BIOCONTROL | MICROBIOLOGY | ANTIBIOTIC COMPLEX | one factor at a time method | HSAF | cultural condition optimization | EXOPOLYSACCHARIDE PRODUCTION | BACILLUS-SUBTILIS | DIHYDROMALTOPHILIN | ACID PRODUCTION | orthogonal matrix method | BIOLOGICAL-CONTROL | STRAIN | Lysobacter enzymogenes OH11 | MYCELIAL GROWTH
Journal Article
Biological Control, ISSN 1049-9644, 05/2018, Volume 120, pp. 52 - 58
Clp was a bone fide downstream regulator of the Rpf/LeDSF signaling to modulate the biosynthesis of HSAF (indicted by blue arrow). However, regulations of Clp... 
Signaling | LeDSF | Lysobacter enzymogenes | Clp | Biocontrol | BACTERIA | MOLECULE | IDENTIFICATION | VIRULENCE | ENTOMOLOGY | BIOLOGICAL-CONTROL AGENT | XANTHOMONAS-CAMPESTRIS | PATHOGENICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOSYNTHESIS | CELL-CELL COMMUNICATION | ANTIMICROBIAL ACTIVITY
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2014, Volume 53, Issue 19, pp. 4840 - 4844
Ikarugamycin is a member of the polycyclic tetramate macrolactams (PTMs) family of natural products with diverse biological activities. The biochemical... 
heterologous expression | ikarugamycin | reductive cyclization | polycyclic tetramate macrolactams | biosynthesis | LACTAM | HSAF | COEXPRESSION | LYSOBACTER-ENZYMOGENES C3 | TETRAMATE MACROLACTAMS | CHEMISTRY, MULTIDISCIPLINARY | Cyclization | Oxidation-Reduction | Lactams - metabolism | Physiological aspects | Enzymes | Biosynthesis
Journal Article
by Feng, T and Han, Y and Li, BQ and Li, ZQ and Yu, YM and Sun, QY and Li, XY and Du, LC and Zhang, XH and Wang, Y
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, ISSN 0099-2240, 12/2019, Volume 85, Issue 23, p. 1
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 128, pp. 105753 - 105759
WAP-8294A is a family of at least 20 cyclic lipodepsipeptides exhibiting potent anti-MRSA activity. These compounds differ mainly in the hydroxylated fatty... 
PERSPECTIVE | MECHANISM | TETRAMATE MACROLACTAM HSAF | LIPOPEPTIDE ANTIBIOTICS | POLYKETIDE | LYSOBACTER-ENZYMOGENES | PIPELINE | ANTIFUNGAL | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | DAPTOMYCIN
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 06/2016, Volume 16, Issue 15, pp. 1727 - 1739
Polycyclic tetramate macrolactams (PTMs), a widely distributed class of structurally complex natural products exhibiting diverse biological activities, share a... 
Polycyclic tetramate macrolactams | Bioactivity | Biosynthesis | Cyclization | Natural products | Genome mining | CHEMISTRY, MEDICINAL | POLYKETIDE SYNTHASE | IRIDOID BIOSYNTHESIS | STRUCTURE ELUCIDATION | MARINE SPONGE | LYSOBACTER-ENZYMOGENES C3 | GENE-CLUSTER | 4+2 CYCLOADDITION | ENANTIOSELECTIVE TOTAL-SYNTHESIS | REDUCTIVE CYCLIZATION | IKARUGAMYCIN BIOSYNTHESIS
Journal Article