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Thyroid, ISSN 1050-7256, 05/2013, Volume 23, Issue 5, pp. 617 - 619
Background: One of the adverse effects of radioactive iodine ( 131 I) treatment in patients with thyroid cancer is damage to the salivary and lacrimal glands.... 
Thyroid Radiology and Nuclear Medicine | BIOKINETICS | I-131 | RADIOIODINE THERAPY | ENDOCRINOLOGY & METABOLISM | SJOGRENS-SYNDROME | HORMONE WITHDRAWAL | CANCER | DOSIMETRY | Lacrimal Apparatus - radiation effects | Recombinant Proteins - therapeutic use | Salivary Gland Diseases - physiopathology | Prospective Studies | Humans | Middle Aged | Male | Lacrimal Apparatus - physiopathology | Hormone Replacement Therapy | Iodine Radioisotopes - adverse effects | Iodine Radioisotopes - therapeutic use | Lacrimal Apparatus - secretion | Salivary Glands - radiation effects | Lacrimal Apparatus Diseases - physiopathology | Adult | Female | Thyrotropin - therapeutic use | Thyroxine - therapeutic use | Salivary Glands - drug effects | Brazil - epidemiology | Salivary Gland Diseases - epidemiology | Thyroid Neoplasms - surgery | Lacrimal Apparatus - drug effects | Salivary Glands - secretion | Lacrimal Apparatus Diseases - epidemiology | Salivary Gland Diseases - etiology | Thyroid Neoplasms - radiotherapy | Combined Modality Therapy - adverse effects | Thyroidectomy - adverse effects | Hypothyroidism - etiology | Radiation Tolerance - drug effects | Radiopharmaceuticals - administration & dosage | Thyroid Neoplasms - physiopathology | Iodine Radioisotopes - administration & dosage | Lacrimal Apparatus Diseases - prevention & control | Salivary Gland Diseases - prevention & control | Hypothyroidism - drug therapy | Salivary Glands - physiopathology | Radiopharmaceuticals - adverse effects | Dose-Response Relationship, Radiation | Lacrimal Apparatus Diseases - etiology | Radiopharmaceuticals - therapeutic use | Index Medicus
Journal Article
JOURNAL OF LEUKOCYTE BIOLOGY, ISSN 0741-5400, 12/2017, Volume 102, Issue 6, pp. 1411 - 1420
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2013, Volume 171, Issue 3, pp. 269 - 279
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1, pp. 44364 - 44364
The study aimed to investigate the effects of silk fibroin in a mouse model of dry eye. The experimental dry eye mouse model was developed using more than... 
OCULAR SURFACE | IN-VITRO | STEM-CELLS | EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | BONE-MARROW | CORNEAL EPITHELIUM | EXTRACELLULAR-MATRIX | SCAFFOLDS | ESSENTIAL FATTY-ACIDS | Ophthalmic Solutions - pharmacology | Dry Eye Syndromes - immunology | Cell Count | Humans | Tumor Necrosis Factor-alpha - genetics | Cornea - immunology | Matrix Metalloproteinase 9 - immunology | Tears - metabolism | Goblet Cells - drug effects | Male | Goblet Cells - immunology | Dry Eye Syndromes - pathology | Conjunctiva - pathology | Cornea - drug effects | Matrix Metalloproteinase 9 - genetics | Tumor Necrosis Factor-alpha - immunology | Vascular Cell Adhesion Molecule-1 - genetics | Cornea - pathology | Lacrimal Apparatus - pathology | Matrix Metalloproteinase 2 - immunology | Disease Models, Animal | Tears - drug effects | Biomarkers - metabolism | Vascular Cell Adhesion Molecule-1 - immunology | Gene Expression | Lacrimal Apparatus - drug effects | Scopolamine | Conjunctiva - immunology | Anti-Inflammatory Agents - pharmacology | Dry Eye Syndromes - drug therapy | Intercellular Adhesion Molecule-1 - immunology | Fibroins - pharmacology | Lacrimal Apparatus - immunology | Matrix Metalloproteinase 2 - genetics | Animals | Conjunctiva - drug effects | Intercellular Adhesion Molecule-1 - genetics | Dry Eye Syndromes - chemically induced | Mice, Inbred NOD | Mice | Goblet Cells - pathology | Immunohistochemistry | Cornea | Animal models | Goblet cells | Epithelial cells | Inflammation | Conjunctiva | Eye care products | Cell density | Eye | Silk | Lacrimal gland | Rodents | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121470 - e0121470
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e33148 - e33148
Background: Decrease in lacrimal gland secretory function is related to age-induced dry eye disease. Lactoferrin, the main glycoprotein component of tears, has... 
OXIDATIVE DAMAGE | EPITHELIAL-CELLS | GASTROINTESTINAL-TRACT | DISEASE | BIOLOGY | RATS | TEAR FILM | IRON | PROTEIN PROFILES | DRY EYE SYNDROME | BOVINE LACTOFERRIN | Immunohistochemistry | Deoxyguanosine - blood | Gene Expression - drug effects | Anti-Infective Agents - pharmacology | Tumor Necrosis Factor-alpha - genetics | Male | Lactoferrin - administration & dosage | Lactoferrin - pharmacology | Aging | Lacrimal Apparatus Diseases - physiopathology | Deoxyguanosine - analogs & derivatives | Tears - drug effects | Microscopy, Electron, Transmission | Lacrimal Apparatus - drug effects | Administration, Oral | Lacrimal Apparatus - ultrastructure | Mice, Inbred C57BL | Chemokine CCL2 - genetics | Random Allocation | Lacrimal Apparatus - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Lacrimal Apparatus Diseases - prevention & control | Animals | Anti-Infective Agents - administration & dosage | Tears - secretion | Deoxyguanosine - metabolism | Mice | Dietary Supplements | Lacrimal Apparatus Diseases - pathology | Viral antibodies | Lysine | Lactoferrins | Antibodies | Eye diseases | Research | Gene expression | Euthanasia | Oxidative stress | Glands | Preserves | Lipid peroxidation | Lipids | Cardiovascular disease | Metastases | Eye | Proteins | Tearing | Lactoferrin | Rodents | Age | Deoxyribonucleic acid--DNA | Enzymes | Immunoglobulins | Internal medicine | Secretion | Glycoprotein | Oral administration | Inflammation | Tumor necrosis factor-α | Medicine | Lacrimal gland | Deoxyguanosine | Diet | Infiltration | Laboratory animals | Monocyte chemoattractant protein 1 | Tears | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 11/2011, Volume 13, Issue 6, pp. R182 - R182
Introduction: In Sjogren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent... 
Chemokine | Keratoconjuntivitis sicca | Sjogren's syndrome | CXCL13 | NOD mouse | Lymphotoxin-beta | chemokine | LYMPHOID NEOGENESIS | HOMING CHEMOKINES | keratoconjuntivitis sicca | RHEUMATOLOGY | SALIVARY-GLANDS | B-CELLS | TUMOR-NECROSIS-FACTOR | KERATOCONJUNCTIVITIS SICCA | LYMPHOCYTIC INFILTRATION | DENDRITIC CELL NETWORKS | AUTOANTIBODY PRODUCTION | AUTOIMMUNE-DISEASE | Immunohistochemistry | Gene Expression - drug effects | Humans | Middle Aged | Venules - physiology | Tears - metabolism | Endothelium, Vascular - drug effects | Male | Gene Expression Profiling | Sjogren's Syndrome - metabolism | Endothelium, Vascular - physiology | Lymphotoxin beta Receptor - metabolism | Cornea - drug effects | Keratoconjunctivitis Sicca - drug therapy | Mucins - metabolism | Adult | Female | Antibodies, Monoclonal - immunology | Sjogren's Syndrome - genetics | Chemokine CXCL13 - genetics | Lacrimal Apparatus - drug effects | Sjogren's Syndrome - drug therapy | Antibodies, Monoclonal - pharmacology | Keratoconjunctivitis Sicca - metabolism | Keratoconjunctivitis Sicca - genetics | Lacrimal Apparatus - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cornea - metabolism | Venules - metabolism | Animals | Endothelium, Vascular - metabolism | Chemokine CXCL13 - metabolism | Mice, Inbred NOD | Aged | Lymphotoxin beta Receptor - antagonists & inhibitors | Mice | Microscopy, Fluorescence | Mucins - genetics | Lymphotoxin beta Receptor - immunology | Care and treatment | Lacrimal organs | Physiological aspects | Genetic aspects | Research | Diagnosis | Gene expression | Risk factors | Index Medicus | Sjögren’s syndrome
Journal Article
Journal of the American Veterinary Medical Association, ISSN 0003-1488, 06/2016, Volume 248, Issue 11, pp. 1262 - 1266
OBJECTIVE To determine effects of glycopyrrolate administered IM on Schirmer tear test I (STT I) measurements in dogs. DESIGN Prospective clinical study.... 
Animals | Lacrimal Apparatus - drug effects | Prospective Studies | Dogs - physiology | Glycopyrrolate - administration & dosage | Injections, Intramuscular - veterinary | Tears - secretion | Glycopyrrolate - pharmacology | Tears - drug effects
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e64724 - e64724
Chronic graft-versus-host disease (cGVHD), a serious complication following allogeneic HSCT (hematopoietic stem cell transplantation), is characterized by... 
SYSTEM | SHOCK-PROTEIN 47 | HEPATIC STELLATE CELLS | RETINAL INFLAMMATION | DRY EYE | MULTIDISCIPLINARY SCIENCES | MECHANISMS | MICE | EXPRESSION | HUMAN SCLERODERMA | FIBROBLASTS | Liver - pathology | Tetrazoles - pharmacology | Gene Expression - drug effects | Receptor, Angiotensin, Type 2 - immunology | Valsartan | Humans | Male | Angiotensin II Type 1 Receptor Blockers - pharmacology | Graft vs Host Disease - immunology | Angiotensin II Type 2 Receptor Blockers - pharmacology | Liver - immunology | Receptor, Angiotensin, Type 1 - genetics | Liver - drug effects | Receptor, Angiotensin, Type 1 - immunology | Fibrosis - prevention & control | Lacrimal Apparatus - pathology | Disease Models, Animal | Receptor, Angiotensin, Type 2 - genetics | Lung - pathology | Lacrimal Apparatus - drug effects | Histocompatibility Testing | Valine - analogs & derivatives | Lacrimal Apparatus - immunology | Renin-Angiotensin System - genetics | Imidazoles - pharmacology | Fibroblasts - pathology | Graft vs Host Disease - pathology | Animals | Fibroblasts - drug effects | Lung - drug effects | Fibroblasts - immunology | Graft vs Host Disease - prevention & control | Mice | Pyridines - pharmacology | Valine - pharmacology | Lung - immunology | Immunohistochemistry | Histocompatibility antigens | Liver diseases | Analysis | Liver | HLA histocompatibility antigens | Fibrosis | Stem cells | Angiotensin | Transplantation | Hematopoietic stem cells | Graft-versus-host reaction | Animal models | Syngeneic grafts | Pathogenesis | Lung | Glands | Lung transplantation | Two dimensional models | Gallbladder diseases | Histocompatibility antigen H-2 | Minor histocompatibility antigens | Allografts | Epidermal growth factor | Rodents | Angiotensin AT1 receptors | Fibroblasts | Angiotensinogen | Bone marrow | Angiotensin II | Localization | Spleen | Medical research | Hematology | Internal medicine | Lung diseases | Heat shock proteins | Inflammation | Attorneys | Gene expression | Hemopoiesis | Medicine | Polymerase chain reaction | Lacrimal gland | Major histocompatibility complex | Collagen | Angiotensin AT2 receptors | Histocompatibility | Liver transplantation | Index Medicus
Journal Article