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Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 1, pp. 550 - 566
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 08/2017, Volume 259, pp. 76 - 82
PLGA nanotherapeutics though representing a most promising platform for targeted cancer therapy are confronted with low stability and insufficient tumor cell... 
Coating | PLGA nanoparticles | Nanomedicine | Lung cancer | Docetaxel | DOXORUBICIN | POLYMERIC MICELLES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | VITAMIN-E TPGS | BREAST-CANCER | THERAPY | IN-VIVO | PHARMACOLOGY & PHARMACY | CLINICAL TRANSLATION | ANTICANCER DRUG-DELIVERY | PROTEIN DELIVERY | Hyaluronic Acid - therapeutic use | Lung Neoplasms - drug therapy | Drug Carriers - therapeutic use | Nanoparticles - chemistry | Humans | Lung Neoplasms - metabolism | Drug Carriers - administration & dosage | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Polyglycolic Acid - therapeutic use | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Taxoids - therapeutic use | Nanoparticles - therapeutic use | Antineoplastic Agents - pharmacokinetics | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | A549 Cells | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Hyaluronic Acid - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Taxoids - pharmacokinetics | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Tumor Burden - drug effects | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Lactic Acid - therapeutic use | Antimitotic agents | Chemotherapy | Antineoplastic agents | Hyaluronic acid | Cancer | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2007, Volume 123, Issue 1, pp. 19 - 26
Polymeric micelles were constructed from poly( -lactic acid) (PLA; 3K)- -poly(ethylene glycol) (PEG; 2K)- -poly( -histidine) (polyHis; 5K) as a tumor... 
Flower-like micelle | Triggered drug release | Poly( l-histidine)- b-PEG- b-poly( l-lactic acid) triblock copolymer | Tumor pH | Poly(l-histidine)-b-PEG-b-poly(l-lactic acid) triblock copolymer | ASSOCIATIVE POLYMERS | SENSITIVE POLYMERIC MICELLES | SOLID TUMORS | poly(L-histidine)-b-PEG-b-poly(L-lactic acid) triblock copolymer | BLOCK-COPOLYMER MICELLES | CHEMISTRY, MULTIDISCIPLINARY | triggered drug release | IN-VITRO | DEPENDENT AGGREGATION | ACETATE NANOPARTICLES PAN | PHARMACOLOGY & PHARMACY | tumor pH | POORLY SOLUBLE DRUGS | EXTRACELLULAR PH | DRUG-DELIVERY SYSTEMS | flower-like micelle | Histidine - administration & dosage | Cell Survival - drug effects | Polymers - administration & dosage | Lactic Acid - chemistry | Humans | Polyethylene Glycols - chemistry | Antineoplastic Agents - administration & dosage | Antineoplastic Agents - chemistry | Polyethylene Glycols - administration & dosage | Neoplasms - drug therapy | Hydrogen-Ion Concentration - drug effects | Micelles | Cell Line, Tumor | Polyesters | Polymers - chemistry | Histidine - chemistry | Neoplasms - pathology | Lactic Acid - administration & dosage | Cell Survival - physiology | Drugs | Ethylene glycol | Drug delivery systems | Block copolymers | Organic acids | Vehicles | Tumors | Index Medicus | Poly(L-histidine)-b-PEG-b-poly(L-lactic acid) triblock copolymer
Journal Article
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 03/2012, Volume 158, Issue 2, pp. 336 - 345
The objective of the present study was to evaluate the effect of oleic acid modified polymeric bilayered nanoparticles (NPS) on combined delivery of two... 
Polymeric nanoparticles | Allergic contact dermatitis | PLGA | Chitosan | Oleic acid | Topical skin delivery | DRUG-DELIVERY | STRATUM-CORNEUM | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | LANGERHANS CELLS | IN-VITRO | PHARMACOLOGY & PHARMACY | THIOLATED GELATIN NANOPARTICLES | SUBSTANCE-P | TOPICAL DELIVERY | SKIN PENETRATION ENHANCEMENT | Nanoparticles - chemistry | Polylactic Acid-Polyglycolic Acid Copolymer | Skin - metabolism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Administration, Cutaneous | Succinimides - chemistry | Ketoprofen - chemistry | Skin Absorption - drug effects | Succinimides - administration & dosage | Substance P - analogs & derivatives | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Dermatitis, Allergic Contact - drug therapy | Lactic Acid - chemistry | Oleic Acid - administration & dosage | Mice, Inbred C57BL | Analgesics - administration & dosage | Ketoprofen - administration & dosage | Rats | Dinitrofluorobenzene | Animals | Dermatitis, Allergic Contact - etiology | Analgesics - chemistry | Polyglycolic Acid - chemistry | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Mice | Nanoparticles - administration & dosage | Substance P - chemistry | Oleic Acid - chemistry | Substance P - administration & dosage | Drugs | Drug delivery systems | Dermatology | Dermatologic agents | Raman spectroscopy | Fatty acids | Transdermal medication | Ketoprofen | Vehicles | Nanoparticles | Unsaturated fatty acids | Monounsaturated fatty acids | Analysis | Formulae, receipts, prescriptions | Skin | Index Medicus | chitosan
Journal Article
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 10/2015, Volume 32, Issue 10, pp. 3376 - 3390
The major hurdle of current drug carrier against hepatocellular carcinoma (HCC) is the lack of specific and selective drug delivery to HCC. In this study, a... 
Biochemistry, general | Biomedical Engineering | pH-sensitive | Biomedicine | Pharmacy | Medical Law | glycyrrhetinic acid | Pharmacology/Toxicology | micelles | hepatocellular carcinoma | andrographolide | INDOCYANINE GREEN | DOXORUBICIN | BIODISTRIBUTION | GLYCOL | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | IN-VITRO | PHARMACOLOGY & PHARMACY | COPOLYMER MICELLES | EXPRESSION | Histidine - administration & dosage | Humans | Drug Carriers - administration & dosage | Polyethylene Glycols - chemistry | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | Carcinoma, Hepatocellular - drug therapy | Liver - drug effects | Micelles | Polyesters - administration & dosage | Glycyrrhetinic Acid - chemistry | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Lactic Acid - chemistry | Acids - chemistry | Glycyrrhetinic Acid - administration & dosage | Liver Neoplasms - drug therapy | Antineoplastic Agents - chemistry | Acids - administration & dosage | Polyethylene Glycols - administration & dosage | Polyesters - chemistry | Animals | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Histidine - chemistry | Drug Delivery Systems - methods | Hydrogen-Ion Concentration | Drugs | Ethylene glycol | Liver cancer | Drug delivery systems | Liver | Hepatoma | Vehicles | Pharmacology | Cancer therapies | Index Medicus
Journal Article
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 134, Issue 2, pp. 81 - 90
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 06/2012, Volume 81, Issue 2, pp. 248 - 256
Schematic illustration of drug-loaded folic acid targeted nanoparticles of mixed lipid-shell and PLGA core (FLPNPs). A functional drug carrier comprised of... 
Drug delivery | PLGA | Nanoparticle | Paclitaxel | GYNECOLOGIC-ONCOLOGY-GROUP | BIODEGRADABLE MICROSPHERES | DRUG-DELIVERY | CONTROLLED-RELEASE | PHASE-II | LIPOSOMAL DAUNORUBICIN | CANCER | RECURRENT | ENDOTHELIAL-CELLS | METASTATIC NASOPHARYNGEAL CARCINOMA | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Nanoparticles - chemistry | Humans | Drug Carriers - administration & dosage | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Tissue Distribution | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Lipids - chemistry | Female | Paclitaxel - administration & dosage | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Lactic Acid - chemistry | Drug Compounding - methods | Chitosan - administration & dosage | Antineoplastic Agents, Phytogenic - chemistry | Lipids - administration & dosage | Mice, SCID | Chemistry, Pharmaceutical | Polyethylene Glycols - administration & dosage | Particle Size | Animals | Chitosan - chemistry | Polyglycolic Acid - chemistry | Cell Line, Tumor | Folic Acid - metabolism | Polymers - chemistry | Mice | Nanoparticles - administration & dosage | HeLa Cells | Drug Delivery Systems - methods | Drugs | Phosphates | Drug delivery systems | Leukemia | Liquid chromatography | Permeability | Chromatography | Folic acid | Vehicles | Nanoparticles | Lysine | Fluorescein | Dimethyl sulfoxide | Lymphomas | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 05/2017, Volume 523, Issue 1, pp. 300 - 309
Metastasis impedes the successful chemotherapy for breast cancer. In this study, an Akt inhibitor (quercetin, Qu) was co-delivered with a chemotherapeutic... 
Metastasis docetaxel | Breast cancer | Akt/MMP-9 pathway | Hyaluronic acid | Quercetin | MMP-9 EXPRESSION | TARGETED DRUG-DELIVERY | POLYMERIC MICELLES | CELLULAR UPTAKE | COLON-CANCER | TUMOR XENOGRAFTS | IN-VIVO | COMBINATION CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | PI3K/AKT SIGNALING PATHWAY | Alct/MMP-9 pathway | Polyethylenes - administration & dosage | Antioxidants - chemistry | Nanoparticles - chemistry | Apoptosis - drug effects | Matrix Metalloproteinase Inhibitors - administration & dosage | Matrix Metalloproteinase Inhibitors - pharmacokinetics | Antineoplastic Agents - administration & dosage | Breast Neoplasms | Polyethylenes - pharmacokinetics | Lactic Acid - pharmacokinetics | Matrix Metalloproteinase 9 - metabolism | Quercetin - pharmacokinetics | Imines - chemistry | Quercetin - administration & dosage | Female | Antineoplastic Agents - pharmacokinetics | Proto-Oncogene Proteins c-akt - metabolism | Lactic Acid - administration & dosage | Polyethylenes - chemistry | Wound Healing - drug effects | Imines - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Quercetin - chemistry | Hyaluronic Acid - chemistry | Matrix Metalloproteinase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Imines - pharmacokinetics | Taxoids - pharmacokinetics | Cell Movement - drug effects | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Polyglycolic Acid - chemistry |