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1. Full Text Treatment for mitochondrial disorders
by Pfeffer, Gerald and Majamaa, Kari and Turnbull, Douglass M and Thorburn, David and Chinnery, Patrick F
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2012, Volume 4, Issue 4, p. CD004426
Background Mitochondrial respiratory chain disorders are the most prevalent group of inherited neurometabolic diseases. They present with central and... 
Mitochondrial Diseases [drug therapy] | Humans | Dichloroacetate [therapeutic use] | Creatine [therapeutic use] | KEARNS-SAYRE SYNDROME | PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA | MEDICINE, GENERAL & INTERNAL | CONGENITAL LACTIC-ACIDOSIS | Sarcosine [analogs & derivatives; therapeutic use] | MAGNETIC-RESONANCE-SPECTROSCOPY | Ubiquinone [therapeutic use] | DOUBLE-BLIND | STROKE-LIKE EPISODES | HEREDITARY OPTIC NEUROPATHY | DNA MUTATIONS | COMPLEX-I DEFICIENCY | COENZYME Q TREATMENT | Mitochondrial Diseases - drug therapy | Sarcosine - therapeutic use | Ubiquinone - analogs & derivatives | Ubiquinone - therapeutic use | Creatine - therapeutic use | Sarcosine - analogs & derivatives | Dichloroacetic Acid - therapeutic use | Randomized Controlled Trials as Topic | Thioctic Acid - therapeutic use
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2. Full Text Hyaluronic acid coated PLGA nanoparticulate docetaxel effectively targets and suppresses orthotopic human lung cancer
by Wu, Jintian and Deng, Chao and Meng, Fenghua and Zhang, Jian and Sun, Huanli and Zhong, Zhiyuan
Journal of Controlled Release, ISSN 0168-3659, 08/2017, Volume 259, pp. 76 - 82
PLGA nanotherapeutics though representing a most promising platform for targeted cancer therapy are confronted with low stability and insufficient tumor cell... 
Coating | PLGA nanoparticles | Nanomedicine | Lung cancer | Docetaxel | DOXORUBICIN | POLYMERIC MICELLES | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | VITAMIN-E TPGS | BREAST-CANCER | THERAPY | IN-VIVO | PHARMACOLOGY & PHARMACY | CLINICAL TRANSLATION | ANTICANCER DRUG-DELIVERY | PROTEIN DELIVERY | Hyaluronic Acid - therapeutic use | Lung Neoplasms - drug therapy | Drug Carriers - therapeutic use | Nanoparticles - chemistry | Humans | Lung Neoplasms - metabolism | Drug Carriers - administration & dosage | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Polyglycolic Acid - therapeutic use | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Taxoids - therapeutic use | Nanoparticles - therapeutic use | Antineoplastic Agents - pharmacokinetics | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Taxoids - chemistry | A549 Cells | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Lactic Acid - chemistry | Hyaluronic Acid - chemistry | Antineoplastic Agents - chemistry | Hyaluronic Acid - pharmacokinetics | Taxoids - pharmacokinetics | Taxoids - administration & dosage | Animals | Polyglycolic Acid - pharmacokinetics | Tumor Burden - drug effects | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Lactic Acid - therapeutic use | Antimitotic agents | Chemotherapy | Antineoplastic agents | Hyaluronic acid | Cancer
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3. Full Text PLGA-based nanoparticles: An overview of biomedical applications
by Danhier, Fabienne and Ansorena, Eduardo and Silva, Joana M and Coco, Régis and Le Breton, Aude and Préat, Véronique
Journal of Controlled Release, ISSN 0168-3659, 07/2012, Volume 161, Issue 2, pp. 505 - 522
Poly(lactic-co-glycolic acid) (PLGA) is one of the most successfully developed biodegradable polymers. Among the different polymers developed to formulate... 
Nanoparticles | Drug delivery | Targeting | Poly(lactic-co-glycolic acid) | HUMAN DENDRITIC CELLS | GENE DELIVERY | DRUG-DELIVERY | NEUROTROPHIC FACTOR | SPINAL-CORD | SEQUENTIAL BMP-2/BMP-7 DELIVERY | BIODEGRADABLE NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | Bacterial Infections - drug therapy | Cardiovascular Diseases - drug therapy | Humans | Polyglycolic Acid - therapeutic use | Drug Delivery Systems | Neoplasms - drug therapy | Brain Diseases - drug therapy | Animals | Vaccination - methods | Inflammation - drug therapy | Nanoparticles - therapeutic use | Nanomedicine - methods | Lactic Acid - therapeutic use | Drugs | Care and treatment | Drug delivery systems | Vehicles | Cancer | Biomedical engineering | Biodegradability | Macromolecules | Vaccination | Inflammation | Hydrophobicity | Drug development | Cancer vaccines | Reviews | nanoparticles | Surface properties | Biocompatibility | polylactide-co-glycolide | Controlled release
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4. Full Text The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment
by Zhang, Xudong and Dong, Yichen and Zeng, Xiaowei and Liang, Xin and Li, Xiaoming and Tao, Wei and Chen, Hongbo and Jiang, Yuyang and Mei, Lin and Feng, Si-Shen
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 6, pp. 1932 - 1943
Abstract Nanoparticles of biodegradable polymers (NPs) have been widely used for drug delivery. However, there has been little research on their fate after... 
Advanced Basic Science | Dentistry | Cancer nanotechnology | Endocytosis | Pharmaceutical nanotechnology | Nanomedicine | Chloroquine | 3-Methyladenine | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | QUANTIFICATION | RELEASE | MACROAUTOPHAGY | VITAMIN-E TPGS | CELL-DEATH | BREAST-CANCER | PROTEINS | COPOLYMER | INTRACELLULAR TRAFFICKING | PLGA NANOPARTICLES | Nanoparticles - chemistry | Humans | Polyglycolic Acid - pharmacology | Immunoblotting | Polyglycolic Acid - therapeutic use | Adenine - chemistry | Autophagy - drug effects | Chloroquine - pharmacology | Polymers - therapeutic use | Adenine - therapeutic use | Female | Lactic Acid - pharmacology | Adenine - analogs & derivatives | Lactic Acid - chemistry | Chloroquine - therapeutic use | Drug Delivery Systems - standards | Adenine - pharmacology | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Polyglycolic Acid - chemistry | Chloroquine - chemistry | Cell Line, Tumor | Polymers - chemistry | Lactic Acid - therapeutic use | Nanoparticles | Drugs | Drug delivery systems | Analysis | Polymer industry | Polymers | Cells | Vehicles
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5. Full Text Review article: probiotics for the treatment of irritable bowel syndrome – focus on lactic acid bacteria
by Clarke, G and Cryan, J. F and Dinan, T. G and Quigley, E. M
Alimentary Pharmacology & Therapeutics, ISSN 0269-2813, 02/2012, Volume 35, Issue 4, pp. 403 - 413
Summary Background Irritable bowel syndrome (IBS) is a poorly understood, yet highly prevalent functional gastrointestinal disorder (FGID). The withdrawal, due... 
LACTOBACILLUS-PLANTARUM 299V | CLINICAL-TRIAL | FERMENTED MILK | DOUBLE-BLIND | BARRIER FUNCTION | PHARMACOLOGY & PHARMACY | RANDOMIZED CONTROLLED-TRIAL | QUALITY-OF-LIFE | GUT MICROBIOTA | BIFIDOBACTERIUM-INFANTIS | GASTROENTEROLOGY & HEPATOLOGY | FUNCTIONAL GASTROINTESTINAL DISORDERS | Animals | Irritable Bowel Syndrome - therapy | Humans | Lactic Acid - metabolism | Probiotics - therapeutic use | Treatment Outcome | Lactic Acid - therapeutic use | Lactobacillus | Randomized Controlled Trials as Topic
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6. Full Text Superparamagnetic PLGA-iron oxide microcapsules for dual-modality US/MR imaging and high intensity focused US breast cancer ablation
by Sun, Yang and Zheng, Yuanyi and Ran, Haitao and Zhou, Yang and Shen, Hongxia and Chen, Yu and Chen, Hangrong and Krupka, Tianyi M and Li, Ao and Li, Pan and Wang, Zhibiao and Wang, Zhigang
Biomaterials, ISSN 0142-9612, 2012, Volume 33, Issue 24, pp. 5854 - 5864
Abstract Organic/inorganic, hybrid, multifunctional, material-based platforms combine the merits of diverse functionalities of inorganic nanoparticles and the... 
Advanced Basic Science | Dentistry | Fe3O4 | HIFU | PLGA | MRI | Ultrasound imaging | Cancer therapy | Fe | O | SURGERY | ULTRASOUND CONTRAST AGENT | MATERIALS SCIENCE, BIOMATERIALS | SOLID TUMORS | FEASIBILITY | ENGINEERING, BIOMEDICAL | MICROBUBBLE AGENT | NANOCAPSULES | NANOPARTICLES | IN-VITRO | THERAPY | LIVER | Breast Neoplasms - surgery | Rabbits | Capsules - therapeutic use | Lactic Acid - chemistry | Breast - surgery | Humans | Ultrasonography, Mammary | Magnetic Resonance Imaging - methods | Capsules - chemistry | Ferric Compounds - chemistry | Polyglycolic Acid - therapeutic use | Animals | Breast Neoplasms - pathology | Polyglycolic Acid - chemistry | Ferric Compounds - therapeutic use | Contrast Media - chemistry | Contrast Media - therapeutic use | Female | Breast Neoplasms - diagnosis | Breast Neoplasms - diagnostic imaging | High-Intensity Focused Ultrasound Ablation - methods | Lactic Acid - therapeutic use | Breast - pathology | Ablation (Surgery) | Diagnostic imaging | Breast cancer | Biological products | Magnetic resonance imaging | Health aspects
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7. Full Text Bioabsorbable radiopaque water-responsive shape memory embolization plug for temporary vascular occlusion
by Wong, Yee Shan and Salvekar, Abhijit Vijay and Zhuang, Kun Da and Liu, Hui and Birch, William R and Tay, Kiang Hiong and Huang, Wei Min and Venkatraman, Subbu S
Biomaterials, ISSN 0142-9612, 2016, Volume 102, pp. 98 - 106
Abstract We describe the preparation, characterization and evaluation of a biodegradable radiopaque water-triggered shape memory embolization plug for... 
Advanced Basic Science | Dentistry | Embolization | Shape-memory | Biodegradable | PEG hydrogel | Poly(lactide-co- glycolide) | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | DEVICE | COMPOSITES | FILLER | MECHANICAL-PROPERTIES | PEGDA HYDROGELS | FILMS | POLYMER | Poly(lactide-co-glycolide) | Rabbits | Lactic Acid - chemistry | Biocompatible Materials - chemistry | Polyethylene Glycols - chemistry | Polyglycolic Acid - therapeutic use | Polyethylene Glycols - therapeutic use | Animals | Polyglycolic Acid - chemistry | Water - chemistry | Biocompatible Materials - therapeutic use | Lactic Acid - therapeutic use | Hydrogels - therapeutic use | Embolization, Therapeutic - methods | Hydrogels - chemistry | Ethylene glycol | Mechanical engineering | Aerospace engineering | Occlusion | Shape memory | Prototypes | Imaging | Feasibility studies | Biocompatibility | In vivo methods and tests | Devices
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8. Poly(lactic acid) and poly(lactic-co-glycolic acid) particles as versatile carrier platforms for vaccine delivery
by Pavot, Vincent and Berthet, Morgane and Rességuier, Julien and Legaz, Sophie and Handké, Nadège and Gilbert, Sarah C and Paul, Stéphane and Verrier, Bernard
Nanomedicine, ISSN 1743-5889, 12/2014, Volume 9, Issue 17, pp. 2703 - 2718
The development of safe and effective vaccines for cancer and infectious diseases remains a major goal in public health. Over the last two decades, controlled... 
vaccine delivery | biodegradable | controlled release | PLGA | PLA | immune response | particles | adjuvants | DENDRITIC CELLS | PLA NANOPARTICLES | CONTROLLED-RELEASE | NANOSCIENCE & NANOTECHNOLOGY | BIODEGRADABLE NANOPARTICLES | LECTIN RECEPTORS | PLGA-BASED NANOPARTICLES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | PLA/PLGA MICROSPHERES | ANTIBODY-RESPONSES | Lactic Acid - chemistry | Dendritic Cells - immunology | Humans | Vaccines - immunology | Polyglycolic Acid - therapeutic use | Vaccines - therapeutic use | Drug Carriers | Drug Delivery Systems | Immunity, Cellular - immunology | Microspheres | Polymers - therapeutic use | Immunity, Cellular - drug effects | Vaccines - chemistry | Adjuvants, Immunologic - chemistry | Polyglycolic Acid - chemistry | Polyesters | Antigens - immunology | Polymers - chemistry | Lactic Acid - therapeutic use | Adjuvants, Immunologic - therapeutic use
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9. Full Text The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus
by Look, Michael and Saltzman, W. Mark and Craft, Joe and Fahmy, Tarek M
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 3, pp. 1089 - 1095
Abstract Targeting dendritic cells with nanoparticles is an attractive modality for instigating immunity or inducing immunosuppression. An important aspect of... 
Advanced Basic Science | Dentistry | Lupus | Nanoparticles | Autoimmune disease | Mycophenolic acid | Immunosuppressives | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | ALLOGRAFT SURVIVAL | ANTIGENS | MAMMALIAN-CELLS | CARBON NANOTUBES | DELIVERY | IMMUNE | NANOPARTICLES | IN-VIVO | POLY(LACTIC-CO-GLYCOLIC ACID) | Nanoparticles Mycophenolic acid | Dendritic Cells - immunology | Immunosuppressive Agents - therapeutic use | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Polyethyleneimine - chemistry | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Dendritic Cells - drug effects | Female | Polyglycolic Acid - metabolism | Mycophenolic Acid - administration & dosage | Dendritic Cells - metabolism | Immunosuppressive Agents - administration & dosage | Polyethylene Glycols - metabolism | Drug Carriers - metabolism | Polyethyleneimine - metabolism | Lactic Acid - chemistry | Lactic Acid - metabolism | Mice, Inbred C57BL | Cells, Cultured | Permeability | Mice, Inbred NZB | Immunosuppression | Animals | Mycophenolic Acid - therapeutic use | Polyglycolic Acid - chemistry | Mice | Mice, Inbred BALB C | Tracers (Biology) | Dendritic cells | Immunotherapy | Health aspects | Immunosuppressive agents | Biomedical engineering
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