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Applied and Environmental Microbiology, ISSN 0099-2240, 03/2018, Volume 84, Issue 5
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ISSN 0005-2736, 05/2016, Volume 1858, Issue 5, pp. 947 - 957
Understanding the mode of action of antibiotics is becoming more and more important in the time that microorganisms start to develop resistance. One very well... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | NUKACIN ISK-1 | PORE FORMATION | Lantibiotics | ANTIBIOTIC NISIN | CELL-WALL BIOSYNTHESIS | Peptidoglycan | CONFORMATIONAL-CHANGES | BIOPHYSICS | Defensins | Antibiotics | ANTIBACTERIAL ACTIVITY | HUMAN BETA-DEFENSIN-3 | Bacteriocins | LANTIBIOTIC LACTICIN-3147 | ANTIMICROBIAL ACTIVITY | PEPTIDOGLYCAN-BIOSYNTHESIS
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 05/2016, Volume 1858, Issue 5, pp. 947 - 957
Understanding the mode of action of antibiotics is becoming more and more important in the time that microorganisms start to develop resistance. One very well... 
Peptidoglycan | Defensins | Antibiotics | Lantibiotics | Bacteriocins | Peptides | Drug resistance in microorganisms
Journal Article
Organic Letters, ISSN 1523-7060, 12/2018, Volume 20, Issue 23, pp. 7478 - 7482
A one-pot, high-yield procedure for synthesizing lanthionine-containing peptides was developed. It relies on the S-alkylation of cysteine-containing peptides... 
DESIGN | BIOSYNTHESIS | MODE | CHEMISTRY, ORGANIC | LANTIBIOTICS | ZEOLITES | STEREOSELECTIVE-SYNTHESIS
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2018, Volume 62, Issue 12
Mutacin 1140, a member of the epidermin family of type AI lantibiotics, has a broad spectrum of activity against Gram-positive bacteria. It blocks cell wall... 
Mutacin | Lantibiotics | MRSA | NISIN | BIOSYNTHESIS | lantibiotics | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | PHARMACODYNAMICS | LYSOSTAPHIN | MODEL | mutacin
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2018, Volume 74, Issue 31, pp. 4247 - 4258
The microbisporicins are the most potent lantibiotics isolated to-date. Cyclic tetra-, hexa- and octapeptides, inspired by this family of antimicrobial agents,... 
Thioether | Desulfurization | Lantibiotic | Peptide synthesis | PEPTIDE ANTIBIOTIC NISIN | ORTHOGONALLY PROTECTED LANTHIONINES | EPILANCIN 15X | SOLID-PHASE SYNTHESIS | CHEMISTRY, ORGANIC | DISULFIDE | RING-C | CYSTINE | BIOSYNTHESIS | LANTIBIOTICS | DERIVATIVES | Peptides | Sulfur compounds | Analysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 23, pp. 10430 - 10435
Journal Article
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, ISSN 0305-7453, 09/2009, Volume 64, Issue 3, pp. 546 - 551
Objectives: Our goal was to compare the activities of lacticin 3147 and nisin, two of the most well characterized lantibiotics, against antibiotic-resistant... 
INFECTIOUS DISEASES | GLYCOPEPTIDE RESISTANCE | ANTIBIOTICS | PRECURSOR LIPID-II | VRE | VISA | VANCOMYCIN RESISTANCE | MICROBIOLOGY | PORE FORMATION | CLOSTRIDIUM-DIFFICILE | PEPTIDES | MRSA | lantibiotics | PHARMACOLOGY & PHARMACY | LANTIBIOTIC LACTICIN-3147 | GRAM-POSITIVE PATHOGENS | antimicrobial peptides | IN-VITRO ACTIVITY
Journal Article
CHILD`S HEALTH, ISSN 2224-0551, 12/2018, Volume 13, Issue 7, pp. 629 - 634
Background. Streptococcus salivarius K12 (SsK12) is an oral colonizing, persistent, antibiotic-sensitive and safe strain that produces two megaplasmid-encoded... 
lantibiotics | children | pharyngotonsillitis | acute respiratory infections
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 07/2019, Volume 374, pp. 32 - 40
associated disease (CDAD) is the leading infectious cause of antibiotic-associated diarrhea and colitis in the United States. Both the incidence and severity... 
OG253 | Mutacin | Bacteriocin | Lantibiotic | CDAD | Lanthipeptide | Nisin and Toxicokinetics
Journal Article
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 07/2018, Volume 83, Issue 14, pp. 7528 - 7533
Lanthipeptides are a family of ribosomally synthesized peptides that have crucial biological functions. However, due to their complicated structures, the total... 
NISIN | DEHYDROALANINE | PROTEIN | ANALOGS | AMINO-ACIDS | BIOSYNTHESIS | NATIVE CHEMICAL LIGATION | SOLID-PHASE | CHEMISTRY, ORGANIC | LANTIBIOTICS | PEPTIDE NATURAL-PRODUCTS
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2018, Volume 140, Issue 38, pp. 11884 - 11888
Most native producers of ribosomally synthesized and post-translationally modified peptides (RiPPs) utilize N-terminal leader peptides to avoid potential... 
NISIN | MUTAGENESIS | PROTEIN | VARIANTS | BIOSYNTHESIS | HALODURACIN | NUKACIN ISK-1 | LANTIBIOTICS | GENERATION | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | BASIC BIOLOGICAL SCIENCES
Journal Article
Journal Article