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amino acid transporter (19) 19
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l-type amino acid transporter 1 (15) 15
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 8, pp. 2877 - 2887
The transporters for glutamine and essential amino acids, ASCT2 (solute carrier family 1 member 5, SLC1A5) and LAT1 (solute carrier family 7 member 5, SLC7A5),... 
CELL LUNG-CANCER | SURVIVAL | NUTRIENT TRANSPORTERS | METABOLISM | GENETIC DISRUPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | HYPOXIA | EXPRESSION | MTORC1 PATHWAY | CYCLE | Lung Neoplasms - drug therapy | Neoplasm Transplantation | Adenocarcinoma - pathology | Cell Proliferation | Large Neutral Amino Acid-Transporter 1 - metabolism | Colonic Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Glutamine - metabolism | Lung Neoplasms - pathology | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Colonic Neoplasms - metabolism | Adenocarcinoma - metabolism | Gene Deletion | Membrane Transport Modulators - pharmacology | Minor Histocompatibility Antigens - genetics | Female | Antineoplastic Agents - pharmacology | Clone Cells | Amino Acid Transport System ASC - genetics | Neoplasm Proteins - genetics | Recombinant Proteins - metabolism | Absorption, Physiological - drug effects | Amino Acid Transport System ASC - antagonists & inhibitors | Recombinant Proteins - chemistry | Amino Acid Transport System ASC - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Gene Knockout Techniques | Adenocarcinoma - drug therapy | Mechanistic Target of Rapamycin Complex 1 - metabolism | Mechanistic Target of Rapamycin Complex 1 - agonists | Minor Histocompatibility Antigens - metabolism | Animals | Mice, Nude | Colonic Neoplasms - pathology | CRISPR-Cas Systems | Cell Line, Tumor | Large Neutral Amino Acid-Transporter 1 - chemistry | Index Medicus | LAT1 | amino acid | ASCT2 | mammalian target of rapamycin (mTOR) | cancer | cell metabolism | amino acid transport | Cell Biology
Journal Article
Anticancer Research, ISSN 0250-7005, 12/2010, Volume 30, Issue 12, pp. 4819 - 4828
Background: L-type amino acid transporter I (LAT1) is highly expressed in various human neoplasms. Antitumor activity of inhibiting LAT1 was analyzed in... 
EGFR mutation | LAT1 | NSCLC | MTOR | Non-small cell lung cancer | non-small cell lung cancer | MTOR PATHWAY | PULMONARY ADENOCARCINOMA | TUMORS | HEAVY-CHAIN | ONCOLOGY | mTOR | CHAIN CD98 EXPRESSION | SMART-AMPLIFICATION PROCESS | PROGNOSTIC-SIGNIFICANCE | MUTATIONS | CARCINOMA | Immunohistochemistry | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | TOR Serine-Threonine Kinases - metabolism | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Lung Neoplasms - pathology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Fusion Regulatory Protein-1 - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Leucine - pharmacokinetics | RNA, Messenger - biosynthesis | Aged, 80 and over | Adult | Quinazolines - administration & dosage | Amino Acids, Cyclic - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Fusion Regulatory Protein-1 - biosynthesis | Amino Acids, Cyclic - pharmacology | Cell Growth Processes - drug effects | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Large Neutral Amino Acid-Transporter 1 - biosynthesis | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Index Medicus
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 12/2016, Volume 167, Issue 6, pp. 1481 - 1494.e18
Journal Article
Journal Article
Journal Article
Journal Article