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1. Full Text The last universal common ancestor between ancient Earth chemistry and the onset of genetics
by Weiss, Madeline C and Preiner, Martina and Xavier, Joana C and Zimorski, Verena and Martin, William F
PLoS Genetics, ISSN 1553-7390, 08/2018, Volume 14, Issue 8, p. e1007518
All known life forms trace back to a last universal common ancestor (LUCA) that witnessed the onset of Darwinian evolution. One can ask questions about LUCA in... 
PHYLOGENY | BIOLOGICAL EVOLUTION | EUBACTERIAL GENES | COMPARATIVE GENOMICS | GENETICS & HEREDITY | ARCHAEBACTERIAL ORIGIN | TREE | NETWORKS | EMERGENCE | LIFE | PROKARYOTES | Fitness (Genetics) | Last universal common ancestor | Research | Prokaryotes | Analysis | Genetic code | Eukaryotes | Genomics | Ribosomes | Phylogenetics | Genomes | Trends | Phylogeny | Gene expression | Carbon
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2. Full Text Environmental Adaptation from the Origin of Life to the Last Universal Common Ancestor
by Cantine, Marjorie D and Fournier, Gregory P
Origins of Life and Evolution of Biospheres, ISSN 0169-6149, 3/2018, Volume 48, Issue 1, pp. 35 - 54
Extensive fundamental molecular and biological evolution took place between the prebiotic origins of life and the state of the Last Universal Common Ancestor... 
Life Sciences | Biochemistry, general | Last universal common ancestor (LUCA) | Life Sciences, general | Astrophysics and Astroparticles | Origin of life | Environmental adaptation | Earth Sciences, general | Astronomy, Observations and Techniques | REVERSE GYRASE | ISOTOPE EVIDENCE | PREBIOTIC SYNTHESIS | EARLY ARCHEAN ERA | EARLY EARTH | IONIZING-RADIATIONS | COMPARATIVE GENOMICS | AMINO-ACIDS | BIOLOGY | MODEL PROTOCELL MEMBRANES | STRELLEY POOL FORMATION | Genetics | Evolution
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3. Gene content of LUCA, the last universal common ancestor
by Mushegian, Arcady
Frontiers in Bioscience, ISSN 1093-9946, 2008, Volume 13, Issue 12, pp. 4657 - 4666
Comparative genomics and modern phylogenetic approaches allow us to infer the gene content of LUCA, the Last Universal Common Ancestor of all known currently... 
Last universal common ancestor | Phylogeny | Review | LUCA | Horizontal gene transfer | CELLS | BACTERIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALGORITHM | horizontal gene transfer | CELL BIOLOGY | ARCHAEAL | ORIGIN | GENOMES | review | BIOSYNTHESIS | last universal common ancestor | phylogeny | TREE | DUPLICATION | EVOLUTIONARY HISTORY | Protein Biosynthesis | Genomics | Computational Biology | Conserved Sequence | DNA Replication | Gene Transfer, Horizontal | Models, Genetic | Origin of Life | Evolution, Molecular
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4. Full Text Protein Superfamily Evolution and the Last Universal Common Ancestor (LUCA)
by Ranea, Juan A. G and Sillero, Antonio and Thornton, Janet M and Orengo, Christine A
Journal of Molecular Evolution, ISSN 0022-2844, 10/2006, Volume 63, Issue 4, pp. 513 - 525
By exploiting three-dimensional structure comparison, which is more sensitive than conventional sequence-based methods for detecting remote homology, we have... 
Life Sciences | Protein evolution | Ancestral protein families | Ancestral protein functions | Microbiology | Last Universal Common Ancestor | Evolutionary temperature | Protein structural domains | Plant Sciences | Genome comparison | Cell Biology | protein evolution | PERSPECTIVE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIZE | evolutionary temperature | CLASSIFICATION | genome comparison | ancestral protein functions | EVOLUTIONARY BIOLOGY | protein structural domains | DATABASE | REDUCTION | COMPARATIVE GENOMICS | FAMILIES | GENETICS & HEREDITY | GENE-TRANSFER | ancestral protein families | Gene Duplication | Genetic Variation | Protein Structure, Tertiary | Proteins - genetics | Temperature | Proteins - classification | Proteins - chemistry | Genome | Evolution, Molecular | Proteins | Analysis
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5. Full Text Buds of the tree: The highway to the last universal common ancestor
by De Farias, Savio Torres and Prosdocimi, Francisco
International Journal of Astrobiology, ISSN 1473-5504, 07/2016, Volume 16, Issue 2, pp. 105 - 113
The last universal common ancestor (LUCA) has been considered as the branching point on which Bacteria, Archaea and Eukaryotes have diverged. However, the... 
viruses | LUCA | last universal common ancestor | LGT | evolution | hypothesis | lateral gene transfer | tree of life | GENE CONTENT | RNA WORLD | ORIGIN | GEOSCIENCES, MULTIDISCIPLINARY | AMINO-ACIDS | ASTRONOMY & ASTROPHYSICS | BIOLOGY | MISSING LINK | DOMAINS | RIBOSOME | LIFE | Bacteria | Viruses | Eukaryotes | Genomes | Astrobiology
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6. Full Text The redox protein construction kit: pre-last universal common ancestor evolution of energy-conserving enzymes
by Frauke Baymann and Evelyne Lebrun and Myriam Brugna and Barbara Schoepp–Cothenet and Marie–Thérèse Giudici–Orticoni and Wolfgang Nitschke
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, ISSN 0962-8436, 01/2003, Volume 358, Issue 1429, pp. 267 - 274
Genome analyses and the resolution of three–dimensional structures have provided evidence in recent years for hitherto unexpected family relationships between... 
Oxidases | Enzymes | Archaea | Phylogenetics | Evolution | Cytochromes | Bacteria | Formates | Genomes | Arsenites | Last universal common ancestor | Phylogeny | Redox proteins | Evolution of bioenergetic enzymes | PHYLOGENETIC ANALYSIS | COORDINATION | redox proteins | ARSENITE OXIDASE | GENOME SEQUENCE | GENES | BIOLOGY | last universal common ancestor | phylogeny | REDUCTASE | TREE | evolution of bioenergetic enzymes | ALCALIGENES-FAECALIS | PHOTOSYNTHESIS | LIFE | Enzymes - chemistry | Species Specificity | Pteridines - metabolism | Archaea - enzymology | Cytochrome b Group - metabolism | Hydrogenase - metabolism | Metalloproteins - metabolism | Ferritins - metabolism | Ferritins - genetics | Enzymes - genetics | Enzymes - metabolism | Bacteria - metabolism | Coenzymes | Oxidation-Reduction | Oxidoreductases - metabolism | Cytochrome b Group - genetics | Bacteria - genetics | Bacterial Proteins | Archaea - metabolism | Energy Metabolism | Bacteria - enzymology | Protein Conformation | Archaea - genetics | Evolution, Molecular
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7. Full Text A proposal of the proteome before the last universal common ancestor (LUCA)
by De Farias, Sávio Torres and Rêgo, Thais Gaudêncio and José, Marco V
International Journal of Astrobiology, ISSN 1473-5504, 01/2016, Volume 15, Issue 1, pp. 27 - 31
The search for understanding the biological nature of the last universal common ancestor (LUCA) has been a theoretical challenge and has sparked intense debate... 
tRNA | last universal common ancestor | proteome | PREBIOTIC CHEMISTRY | RNA WORLD | ORIGIN | GEOSCIENCES, MULTIDISCIPLINARY | EVOLUTION | DATABASE | GENE | ASTRONOMY & ASTROPHYSICS | BIOLOGY | LIFE | Studies | Molecules | Ribonucleic acid--RNA | Astrobiology
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8. Full Text A minimal estimate for the gene content of the last universal common ancestor—exobiology from a terrestrial perspective
by Ouzounis, Christos A and Kunin, Victor and Darzentas, Nikos and Goldovsky, Leon
Research in Microbiology, ISSN 0923-2508, 2006, Volume 157, Issue 1, pp. 57 - 68
Using an algorithm for ancestral state inference of gene content, given a large number of extant genome sequences and a phylogenetic tree, we aim to... 
Ancestral reconstruction | Last ancestor | Genome comparison | Function annotation | last ancestor | ORGANIC-MOLECULES | MICROBIOLOGY | genome comparison | ancestral reconstruction | ORIGIN | function annotation | EVOLUTION | COMPARATIVE GENOMICS | PROTEIN FAMILIES | DEEP-SEA | INTERSTELLAR GLYCINE | PHYLOGENETIC CLASSIFICATION | DNA-REPAIR | LIFE | Exobiology | Algorithms | Gene Transfer, Horizontal | Earth (Planet) | Phylogeny | Genome | Evolution, Molecular | Genetic research | Carrier proteins | Analysis | Genomics
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9. Full Text Modern mRNA proofreading and repair: Clues that the last universal common ancestor possessed an RNA genome?
by Poole, Anthony M and Logan, Derek T and Biochemistry and Structural Biology and Lund University and Lunds universitet and Biokemi och Strukturbiologi
Molecular Biology and Evolution, ISSN 0737-4038, 06/2005, Volume 22, Issue 6, pp. 1444 - 1455
RNA repair has now been demonstrated to be a genuine biological process and appears to be present in all three domains of life. In this article, we consider... 
Evolution | RNA polymerase | Proofreading | DNA origins | Last Universal Common Ancestor | RNA repair | METAZOAN MITOCHONDRIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TOBACCO MOSAIC VIRUS | DNA-POLYMERASE | evolution | RIBOSOMAL-RNA | RIBONUCLEOTIDE REDUCTASE | EVOLUTIONARY BIOLOGY | REPLICATION PROTEINS | GENETICS & HEREDITY | proofreading | POLYMERASE-II | TRANSCRIPTION FACTOR | HYDROLYTIC CLEAVAGE | Models, Theoretical | RNA Processing, Post-Transcriptional | RNA Editing | RNA, Messenger - genetics | Selection, Genetic | Models, Molecular | DNA-Directed RNA Polymerases - genetics | RNA - genetics | Biological Evolution | DNA Repair | Models, Genetic | Genome | Evolution, Molecular | Biological Sciences | Biologi | Naturvetenskap | Natural Sciences
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10. Full Text From the primordial soup to the latest universal common ancestor
by Vaneechoutte, Mario and Fani, Renato
Research in Microbiology, ISSN 0923-2508, 2009, Volume 160, Issue 7, pp. 437 - 440
This special issue of Research in Microbiology is dedicated to the origin of Life and of microbiology. One hundred and fifty years after Darwin's ‘Origin of... 
Life | Darwin | Last universal common ancestor | Natural selection | Horizontal gene transfer | ORIGIN | EVOLUTION | MICROBIOLOGY | Biological Evolution | Origin of Life | Genetic Speciation | Selection, Genetic | Evolutionary biology
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11. Full Text Cenancestor, the Last Universal Common Ancestor
by Delaye, Luis and Becerra, Arturo
Evolution: Education and Outreach, ISSN 1936-6426, 9/2012, Volume 5, Issue 3, pp. 382 - 388
Darwin suggested that all life on Earth could be phylogenetically related. Modern biology has confirmed Darwin’s extraordinary insight; the existence of a... 
Learning & Instruction | Sociology of Education | Archaea | Cenancestor | Life Sciences | Early evolution of life | Last universal common ancestor | Eukarya | Teaching and Teacher Education | Bacteria | Evolutionary Biology | Education, general | Progenote | Horizontal gene transfer | Genomics
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12. Full Text The origin of life and the last universal common ancestor: do we need a change of perspective?
by Glansdorff, Nicolas and Xu, Ying and Labedan, Bernard
Research in Microbiology, ISSN 0923-2508, 2009, Volume 160, Issue 7, pp. 522 - 528
A complete tree with roots, trunk and crown remains an appropriate model to represent all steps of life's development, from the emergence of a unique genetic... 
Last common ancestor | Prebiotic polymers | Primordial cells | CELL EVOLUTION | MICROBIOLOGY | MODEL | RNA WORLD | GENETIC-CODE | REAPPRAISAL | COMPARATIVE GENOMICS | TREE | SELECTION | HISTORY | PROKARYOTES | Genetic Code | Evolution, Chemical | Origin of Life | Models, Biological | Evolution, Molecular | RNA - genetics | Life Sciences | Microbiology and Parasitology | Biochemistry, Molecular Biology
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13. Full Text The universal ancestor, the deeper nodes of the tree of life, and the fundamental types of primary cells (cellular domains)
by Di Giulio, Massimo
Journal of Theoretical Biology, ISSN 0022-5193, 01/2019, Volume 460, pp. 142 - 143
I have analyzed the deep nodes of the topology of the tree of life as supported by Castelle and Banfield (2018). My arguments imply that the last universal... 
Last universal common ancestor | Progenotes | CPR bacteria | Tree of life | DPANN archaea | TERM PROKARYOTE | EARTH | BACTERIA | ORIGIN | ARCHAEA | BIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | KINDS | Bacteria | Analysis
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14. Full Text Ancient horizontal gene transfer and the last common ancestors Phylogenetics and phylogeography
by Fournier, Gregory P and Andam, Cheryl P and Gogarten, Johann Peter
BMC Evolutionary Biology, 04/2015, Volume 15, Issue 1
Hypnolog | LUCA | Aminoacyl-tRNA synthetase | Last Universal Common Ancestor | Cenancestor | Horizontal gene transfer
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15. Full Text Universal Protein Families and the Functional Content of the Last Universal Common Ancestor
by Kyrpides, Nikos and Overbeek, Ross and Ouzounis, Christos
Journal of Molecular Evolution, ISSN 0022-2844, 10/1999, Volume 49, Issue 4, pp. 413 - 423
The phylogenetic distribution of Methanococcus jannaschii proteins can provide, for the first time, an estimate of the genome content of the last common... 
Last Universal Common Ancestor — Cellular evolution — Metabolic reconstruction — Biochemical pathways — Genomics | Cellular evolution | Biochemical pathways | Genomics | Last Universal Common Ancestor | Metabolic reconstruction | biochemical pathways | CORE | METHANOCOCCUS-JANNASCHII | BIOCHEMISTRY & MOLECULAR BIOLOGY | BACTERIAL GENOMES | ARCHAEON | EVOLUTIONARY BIOLOGY | COMPLETE GENOME SEQUENCE | EVOLUTION | cellular evolution | GENETICS & HEREDITY | metabolic reconstruction | genomics | TRANSCRIPTION FACTOR | LIFE | Genes, Archaeal - genetics | Archaeal Proteins - genetics | Phylogeny | Genome | Archaeal Proteins - classification | Methanococcus - genetics | Databases, Factual | Evolution, Molecular | Proteins | Biochemistry | Evolutionary biology | Cellular biology | Metabolism
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