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The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 28, pp. 23790 - 23807
Lecithin: retinol acyltransferase-like proteins, also referred to as HRAS-like tumor suppressors, comprise a vertebrate subfamily of papain-like or NlpC/P60 thiol proteases that function as phospholipid-metabolizing enzymes... 
ADIPOSE-SPECIFIC PHOSPHOLIPASE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RETINOL ACYLTRANSFERASE | ESCHERICHIA-COLI | BIOCHEMICAL-CHARACTERIZATION | TRUNCATED FORM | ACYL | MODEL | MEMBRANE-LIPIDS | SULFENIC ACIDS | Humans | Molecular Sequence Data | Substrate Specificity | Crystallography, X-Ray | Chromatography, High Pressure Liquid | Acyltransferases - metabolism | Acyltransferases - genetics | Cysteine - genetics | Mass Spectrometry | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Cysteine - metabolism | Phospholipids - metabolism | Acylation | Protein Structure, Tertiary | Amino Acid Sequence | Catalytic Domain | Phospholipases A2, Calcium-Independent - metabolism | Tumor Suppressor Proteins - metabolism | Biocatalysis | Electrophoresis, Polyacrylamide Gel | Enzyme Stability | Models, Molecular | Cysteine - chemistry | Sequence Homology, Amino Acid | Protein Binding | Acyltransferases - chemistry | Phospholipases A2, Calcium-Independent - genetics | Phospholipases A2, Calcium-Independent - chemistry | TOPOLOGY | CATALYSIS | LIPASES | NEOPLASMS | BASIC BIOLOGICAL SCIENCES | RESOLUTION | CRYSTAL STRUCTURE | TRIGLYCERIDES | 60 APPLIED LIFE SCIENCES | LECITHINS | THIOLS | EXPENDITURES | ENZYMES | BIOLOGY | ARCHITECTURE | VERTEBRATES | TARGETS | METABOLIC DISEASES | PROTEINS | LIPIDS | Phosphatidylcholine | Lipids | Enzymology | Lipase | Enzyme Catalysis | Structural Biology
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0143846
Restoring vision in inherited retinal degenerations remains an unmet medical need. In mice exhibiting a genetically engineered block of the visual cycle,... 
Vitamin A - pharmacology | Vitamin A - analogs & derivatives | Humans | Middle Aged | Male | Visual Fields - drug effects | Acyltransferases - metabolism | Acyltransferases - genetics | Retinal Ganglion Cells - pathology | Young Adult | Drug Dosage Calculations | Visual Acuity - drug effects | Adult | Female | cis-trans-Isomerases - metabolism | Anticarcinogenic Agents - adverse effects | Anticarcinogenic Agents - pharmacology | Child | Anticarcinogenic Agents - therapeutic use | Administration, Oral | Retinitis Pigmentosa - drug therapy | Treatment Outcome | Cerebral Cortex - diagnostic imaging | Radiography | Vitamin A - therapeutic use | cis-trans-Isomerases - genetics | Polymorphism, Single Nucleotide | Retinal Neurons - pathology | Vitamin A - adverse effects | Physiological aspects | Research | Retinoids | Lecithin | Drug therapy | Retinitis pigmentosa | Headache | Visual cortex | Disease | Retina | Defects | Acuity | Vitamin A | Coherence length | Hemispheres | Vomiting | Functional magnetic resonance imaging | Eye (anatomy) | Safety | Visual fields | Congenital diseases | Abnormalities | Cortex (occipital) | Oral administration | Visual acuity | Nausea | Metabolism | Acyltransferase | Patients | Hospitals | Optical Coherence Tomography | Vision | Retinal degeneration | Photoreceptors | Genetic engineering | Retinitis | Mutation | Gene therapy | Acetic acid | Structure-function relationships
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