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PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0137592
Background Diagnosing pediatric pneumonia is challenging in low-resource settings. The World Health Organization (WHO) has defined primary end-point... 
C-REACTIVE PROTEIN | PNEUMOCOCCAL CONJUGATE VACCINE | DIAGNOSIS | COMMUNITY-ACQUIRED PNEUMONIA | PUBLIC-HEALTH | EFFICACY | MULTIDISCIPLINARY SCIENCES | PROCALCITONIN | DOUBLE-BLIND | LOWER RESPIRATORY-TRACT | BACTERIAL | Protein Precursors - blood | Humans | Child, Preschool | Infant | Male | Adipokines - blood | Chitinase-3-Like Protein 1 | Endoglin | Likelihood Functions | C-Reactive Protein - metabolism | Receptor, TIE-2 - blood | Pneumonia - diagnosis | Sensitivity and Specificity | Female | Pneumonia - blood | von Willebrand Factor - metabolism | Calcitonin Gene-Related Peptide | Calcitonin - blood | Enzyme-Linked Immunosorbent Assay | Tanzania | Logistic Models | Receptors, Cell Surface - blood | Biomarkers - blood | Fever | Radiography | Regression Analysis | Antigens, CD - blood | Lectins - blood | ROC Curve | Pneumonia - diagnostic imaging | Cohort Studies | Low income groups | Chitinase | Chest | Pneumonia | C-reactive protein | Procalcitonin | Clinical trials | Life assessment | Standard error | Vaccines | Epidemiology | Streptococcus infections | Proteins | Confidence intervals | Health care networks | Classification | Von Willebrand factor | Mathematical models | Bioindicators | Children | Public health | Enzyme-linked immunosorbent assay | Immunization | Statistical analysis | Mortality | Likelihood ratio | Health psychology | Inflammation | Regression analysis | Primary care | Medicine | Studies | Hospitals | Respiratory syncytial virus | Antibiotics | Proteomics | Biomarkers | Plasma levels | Ambulatory care
Journal Article
BioMed Research International, ISSN 2314-6133, 2015, Volume 2015, pp. 490531 - 16
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0120995 - e0120995
Objective We aimed to identify a novel panel of biomarkers predicting renal function decline in type 2 diabetes, using biomarkers representing different... 
GLOMERULAR-FILTRATION-RATE | YKL-40 LEVELS | PLASMA | ENDOTHELIAL DYSFUNCTION | ALBUMINURIA | MICROALBUMINURIA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | CHRONIC KIDNEY-DISEASE | NEPHROPATHY | PROGRESSION | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Bone Morphogenetic Proteins - blood | Diabetic Nephropathies - blood | Diabetic Nephropathies - diagnosis | Adipokines - blood | Chitinase-3-Like Protein 1 | Kidney - metabolism | Diabetic Nephropathies - physiopathology | Adult | Female | Renal Insufficiency, Chronic - diagnosis | Membrane Proteins - blood | Kidney - physiopathology | Natriuretic Peptide, C-Type - blood | Glomerular Filtration Rate | Receptors, Tumor Necrosis Factor, Type I - blood | Risk Factors | Biomarkers - blood | Genetic Markers | Intracellular Signaling Peptides and Proteins - blood | Chemokine CCL2 - blood | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Protein-Tyrosine Kinases - blood | Renal Insufficiency, Chronic - blood | Diabetes Mellitus, Type 2 - diagnosis | Diabetes Mellitus, Type 2 - blood | Lectins - blood | Diabetes Mellitus, Type 2 - physiopathology | Outpatients | Matrix Metalloproteinases, Secreted - blood | Fibrosis | Aged | Connective Tissue Growth Factor - blood | Type 2 diabetes | Complications and side effects | Research | Kidney diseases | Diagnosis | Biological markers | Risk factors | Nephrology | Renal function | Risk | SOST protein | Angiogenesis | Pathways | Mathematical analysis | Data integration | Rodents | Bioindicators | Mathematical models | Protein-tyrosine kinase | Tyrosine | Medical research | Internal medicine | Epidermal growth factor receptors | Diabetes mellitus | Health risks | Connective tissue growth factor | Pharmacology | Shrinkage | Patients | Studies | Nephropathy | Tumor necrosis factor | Pharmacy | Predictions | Biomarkers | Research design | Diabetes | Monocyte chemoattractant protein 1 | Kidney transplantation | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2017, Volume 109, Issue 4, p. djw266
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2017, Volume 37, Issue 8, pp. 1503 - 1512
OBJECTIVE—Phosphatidylserine exposure mediates platelet procoagulant function and regulates platelet life span. Apoptotic, necrotic, and integrin-mediated... 
phosphatidylserine | blood platelet | cell death | cytosol | mitochondrial membrane | PERMEABILITY TRANSITION PORE | ACTIVATION | BLOOD-COAGULATION | INTEGRIN ALPHA(IIB)BETA | PROCOAGULANT PLATELETS | CELL-DEATH | THROMBUS GROWTH | CALCIUM | SURFACE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPOSURE | Crotalid Venoms - pharmacology | Apoptosis - drug effects | Venous Thrombosis - blood | bcl-2 Homologous Antagonist-Killer Protein - genetics | Mitochondria - ultrastructure | Necrosis | Mitochondrial Membranes - drug effects | Cytochromes c - blood | Thrombin - pharmacology | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | bcl-2 Homologous Antagonist-Killer Protein - blood | Platelet Aggregation - drug effects | Blood Platelets - drug effects | Integrins - blood | bcl-2-Associated X Protein - blood | bcl-2-Associated X Protein - genetics | Disease Models, Animal | Cyclophilins - blood | Signal Transduction | Lectins, C-Type | Genotype | Cyclophilins - genetics | Mitochondria - metabolism | Mitochondria - drug effects | Sulfonamides - pharmacology | Piperazines - pharmacology | Mice, Knockout | Mitochondrial Membranes - metabolism | Phenotype | Animals | Blood Coagulation - drug effects | Blood Platelets - metabolism | Blood Platelets - ultrastructure | Venous Thrombosis - genetics | Caspases - blood | Kinetics | Venous Thrombosis - pathology | Phosphatidylserines - blood | platelet | inner mitochondrial membrane
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46740
Significant bone remodeling with disordered osteoclastogenesis has been implicated in the pathogenesis of psoriatic arthritis (PsA). And there is a high... 
RHEUMATOID-ARTHRITIS | LEPTIN | IN-VITRO | RESISTIN | CHEMERIN | SYNOVIAL TISSUE | PLASMA-LEVELS | MULTIDISCIPLINARY SCIENCES | HUMAN ARTICULAR CHONDROCYTES | TNF-ALPHA | SPONDYLITIS RADIOLOGY INDEX | Chemokines - blood | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Male | Adipokines - blood | Young Adult | RANK Ligand - blood | Arthritis, Psoriatic - pathology | Leptin - blood | Osteoprotegerin - blood | Adult | Female | Cytokines - blood | Osteoclasts - pathology | Bone Resorption - blood | Intercellular Signaling Peptides and Proteins | Osteoclasts - metabolism | Adiponectin - blood | Lectins - blood | Analysis of Variance | Arthritis, Psoriatic - blood | Bone Resorption - pathology | GPI-Linked Proteins - blood | Resistin - blood | Aged | Bone Remodeling | Medical research | Tumor necrosis factor | Leptin | Measuring instruments | Medicine, Experimental | B cells | Psoriatic arthritis | Osteoprogenitor cells | Multiple sclerosis | Pathogenesis | Arthritis | Family medical history | Metabolic syndrome | Osteolysis | Blood | Adiponectin | Osteoprotegerin | Bone growth | Immunology | Precursors | Peripheral blood | Biocompatibility | Erosion control | TRANCE protein | Psoriasis | Cytokines | Bone remodelling | Rheumatic diseases | Rheumatology | Tumor necrosis factor-α | Gene expression | Joint diseases | Patients | Hemopoiesis | Serum levels | Studies | Osteoclastogenesis | Radiography | Hospitals | Correlation analysis | Rheumatoid arthritis | Radiographs | Bone | Diabetes | Autoimmune diseases | Pluripotency | Metabolic disorders | Osteogenesis
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 908 - 916
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2012, Volume 130, Issue 6, pp. 1357 - 1366
The MET oncogene is amplified in a fraction of human gastric carcinoma cell lines, with consequent overexpression and constitutive activation of the... 
oncogene addiction | surrogate biomarkers | targeted therapies | Met receptor | CARCINOMA CELLS | NECROSIS-FACTOR-ALPHA | PLASMINOGEN-ACTIVATOR RECEPTOR | INTERLEUKIN-8 | IN-VITRO | ONCOLOGY | AUTOCRINE GROWTH-FACTOR | C-MET | PROSTATE-CANCER | UROKINASE RECEPTOR | CELL-LINE | Mannose-Binding Lectins - metabolism | Proto-Oncogene Proteins c-met - metabolism | Interleukin-8 - genetics | Membrane Glycoproteins - metabolism | Humans | Stomach Neoplasms - metabolism | Chemokine CXCL1 - genetics | Gene Expression Profiling | Sulfones - pharmacology | Interleukin-6 - blood | Biomarkers, Tumor - metabolism | Female | Indoles - pharmacology | Interleukin-8 - metabolism | Chemokine CXCL1 - metabolism | Interleukin-8 - blood | Interleukin-6 - metabolism | Stomach Neoplasms - genetics | Interleukin-6 - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Membrane Glycoproteins - blood | Receptors, Cell Surface - metabolism | Receptors, Cell Surface - blood | Chemokine CXCL1 - blood | Stomach Neoplasms - drug therapy | Membrane Glycoproteins - genetics | Proto-Oncogene Proteins c-met - genetics | Biomarkers, Tumor - blood | Xenograft Model Antitumor Assays | Animals | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - blood | Stomach Neoplasms - blood | Mice, Nude | Proteomics | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Receptors, Cell Surface - genetics | Biomarkers | Kinases | Gene expression | Tumors
Journal Article