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Nature Immunology, ISSN 1529-2908, 12/2013, Volume 14, Issue 12, pp. 1294 - 1301
Tissue-resident memory T cells (TRM cells) provide superior protection against infection in extralymphoid tissues. Here we found that CD103(+)CD8(+) TRM cells... 
MIGRATION | EFFECTOR | INTESTINAL EPITHELIUM | NONLYMPHOID TISSUE | RM CELLS | PERIPHERAL-TISSUES | DIFFERENTIATION | IMMUNOLOGY | LYMPHOCYTE EGRESS | CD103 EXPRESSION | CUTTING EDGE | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - immunology | Oligonucleotide Array Sequence Analysis | Skin - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | Lectins, C-Type - metabolism | Herpesvirus 1, Human - physiology | Integrin alpha Chains - immunology | CD8-Positive T-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Antigens, Differentiation, T-Lymphocyte - metabolism | Mice, Transgenic | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Herpes Simplex - immunology | Mice, Knockout | Cell Differentiation - immunology | Herpes Simplex - virology | Interleukin-15 - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Antigens, CD - immunology | Lectins, C-Type - immunology | Transcriptome - immunology | Lectins, C-Type - genetics | Interleukin-15 - immunology | Cell Differentiation - genetics | Signal Transduction - immunology | Flow Cytometry | Herpesvirus 1, Human - immunology | Receptors, Immunologic - immunology | Skin - virology | Immunologic Memory - immunology | Skin - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Integrin alpha Chains - metabolism | Transcriptome - genetics | Mice, Inbred Strains | Animals | Interleukin-15 - genetics | Receptors, Transforming Growth Factor beta - metabolism | CD8-Positive T-Lymphocytes - virology | Antigens, Differentiation, T-Lymphocyte - genetics | Protein-Serine-Threonine Kinases - immunology | Integrin alpha Chains - genetics | Receptors, Immunologic - metabolism | Index Medicus
Journal Article
Journal of experimental medicine, ISSN 0022-1007, 2008, Volume 205, Issue 7, pp. 1621 - 1634
Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b(-)... 
MEDICINE, RESEARCH & EXPERIMENTAL | IIFN-PRODUCING CELLS | INHALED ANTIGEN | IN-VIVO DEPLETION | ANTIGEN PRESENTATION | STEADY-STATE | IMMUNOLOGY | PULMONARY INFECTION | ANTIBODY-RESPONSE | CD8(+) T-CELLS | RESPIRATORY SYNCYTIAL VIRUS | LANGERHANS CELLS | Dendritic Cells - immunology | Lectins, C-Type - immunology | Male | Lectins, C-Type - genetics | CD11c Antigen - immunology | Trachea - virology | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | CD11b Antigen - genetics | Lung - virology | CD11c Antigen - genetics | Female | CD4-Positive T-Lymphocytes - virology | Dendritic Cells - virology | CD11b Antigen - immunology | Plasma Cells - virology | Antigens, Surface - genetics | Intercellular Signaling Peptides and Proteins - genetics | Antigen Presentation - genetics | Mice, Transgenic | Lymph Nodes - virology | Lymph Nodes - immunology | CD8 Antigens - immunology | Trachea - immunology | Heparin-binding EGF-like Growth Factor | Animals | Mannose-Binding Lectins - genetics | Mannose-Binding Lectins - immunology | CD8-Positive T-Lymphocytes - virology | CD8 Antigens - genetics | Dogs | Antibodies, Viral - immunology | Nucleocapsid Proteins - immunology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Antigens, Surface - immunology | Antibody Formation - genetics | Intercellular Signaling Peptides and Proteins - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Plasma Cells - immunology | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 24, pp. 4751 - 4760
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown... 
INNATE | NATURAL-KILLER-CELLS | INFECTION | HEMATOLOGY | EXPANSION | Receptors, Interleukin-12 - immunology | Antigens, CD - immunology | Interleukin-18 - immunology | Humans | Lectins, C-Type - immunology | Interferon-gamma - metabolism | Interleukin-15 - immunology | Antigens, CD - metabolism | NK Cell Lectin-Like Receptor Subfamily D - immunology | Lectins, C-Type - metabolism | NK Cell Lectin-Like Receptor Subfamily C - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Time Factors | Killer Cells, Natural - immunology | Receptors, Interleukin-12 - genetics | Interferon-gamma - genetics | CD56 Antigen - immunology | Immunologic Memory - immunology | Cytokines - immunology | Interleukin-12 - pharmacology | Receptors, Interleukin-18 - metabolism | CD56 Antigen - metabolism | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-15 - pharmacology | Receptors, Interleukin-12 - metabolism | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-12 - immunology | K562 Cells | Receptors, Interleukin-18 - genetics | Receptors, Interleukin-18 - immunology | Cell Proliferation - drug effects | Interleukin-18 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Cytokines - pharmacology | Index Medicus | Abridged Index Medicus | Immunobiology
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 587 - 601
Mucosal-associated invariant T (MAIT) cells have a semi-invariant TCR V alpha-chain, and their optimal development is dependent upon commensal flora and... 
MYCOBACTERIUM-TUBERCULOSIS | ANTIGEN RECEPTOR RECOGNITION | IMMUNE-RESPONSE | NATURAL-KILLER-CELLS | MAIT CELLS | NK CELLS | MULTIPLE-SCLEROSIS | VITAMIN-B METABOLITES | TCR ALPHA-CHAIN | BACTERIAL-INFECTION | IMMUNOLOGY | Lung - microbiology | Interleukin-18 - immunology | Mycobacterium bovis - immunology | Immunity, Mucosal | Receptors, Antigen, T-Cell, alpha-beta - immunology | Antigens, CD - genetics | Riboflavin - analogs & derivatives | CD4-Positive T-Lymphocytes - immunology | Tuberculosis - pathology | CD4-Positive T-Lymphocytes - microbiology | Signal Transduction | Riboflavin - immunology | Genetic Heterogeneity | Mice, Knockout | Integrin alpha4beta1 - immunology | Lung - drug effects | Receptors, CXCR3 - genetics | Interleukin-12 - immunology | Receptors, CXCR3 - immunology | Hyaluronan Receptors - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Interleukin-18 - genetics | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Interleukin-12 - genetics | Minor Histocompatibility Antigens | Protein Multimerization | Antigens, Ly - genetics | Lectins, C-Type - immunology | Tuberculosis - microbiology | Riboflavin - pharmacology | CD4-Positive T-Lymphocytes - pathology | Lectins, C-Type - genetics | Gene Expression Regulation, Developmental | CD8-Positive T-Lymphocytes - microbiology | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Integrin alpha4beta1 - genetics | Histocompatibility Antigens Class I - genetics | Tuberculosis - veterinary | Hyaluronan Receptors - genetics | NK Cell Lectin-Like Receptor Subfamily B - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | Tuberculosis - immunology | Animals | Antigens, Ly - immunology | NK Cell Lectin-Like Receptor Subfamily B - genetics | CD8-Positive T-Lymphocytes - drug effects | Antigens, Differentiation, T-Lymphocyte - genetics | Immunologic Memory | CD4-Positive T-Lymphocytes - drug effects | Lung - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 1, pp. 221 - 230.e3
Background & Aims Anti–tumor necrosis factor (TNF)α antibodies are effective in treating patients with Crohn's disease whereas soluble TNFα receptors have not... 
Gastroenterology and Hepatology | Autoimmunity | IBD | Inflammatory Response | Type 2 Macrophage | MONOCLONAL-ANTIBODY | POLYMORPHISM | ACTIVE CROHNS-DISEASE | INFLAMMATORY-BOWEL-DISEASE | ACCENT-I | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | TNF-ALPHA | INFLIXIMAB | GASTROENTEROLOGY & HEPATOLOGY | T-LYMPHOCYTES | Cell Proliferation | Certolizumab Pegol | Humans | Lectins, C-Type - immunology | Anti-Inflammatory Agents - immunology | Caspase 3 - immunology | Antibodies, Monoclonal, Humanized | Lymphocyte Activation - immunology | Immunoglobulin Fc Fragments - immunology | Etanercept | Infliximab | Immunoglobulin G - immunology | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Immunosuppressive Agents - pharmacology | Antibodies, Monoclonal - immunology | Macrophages - immunology | Cytokines - immunology | Polyethylene Glycols - pharmacology | Leukocytes, Mononuclear - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Cytokines - secretion | Crohn Disease - immunology | Receptors, Cell Surface - immunology | Immunoglobulin Fab Fragments - pharmacology | Mannose-Binding Lectins - immunology | Receptors, Fc - immunology | Immunosuppressive Agents - immunology | Lymphocyte Activation - drug effects | Caspase 3 - analysis | T-Lymphocytes - immunology | Immunoglobulin Fab Fragments - immunology | Adalimumab | Receptors, Tumor Necrosis Factor - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
NATURE, ISSN 0028-0836, 07/2011, Volume 475, Issue 7354, pp. 110 - U133
High-dose intravenous immunoglobulin is a widely used therapeutic preparation of highly purified immunoglobulin G (IgG) antibodies. It is administered at high... 
IMMUNITY IN-VIVO | ALLERGIC INFLAMMATION | RESPONSES | ANTIINFLAMMATORY ACTIVITY | DC-SIGN | DENDRITIC CELL | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | TYPE-2 IMMUNITY | AUTOIMMUNE-DISEASE | Cell Adhesion Molecules - genetics | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Th2 Cells - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Th2 Cells - drug effects | Interleukins - metabolism | Receptors, IgG - metabolism | Immunoglobulins, Intravenous - metabolism | Lectins, C-Type - metabolism | Immunoglobulin G - immunology | Inflammation - drug therapy | Interleukins - immunology | Basophils - immunology | Arthritis - immunology | Immunoglobulin G - pharmacology | Interleukins - pharmacology | Bone Marrow | Autoimmune Diseases - drug therapy | Macrophages - immunology | Basophils - drug effects | Arthritis - pathology | Interleukin-33 | Immunoglobulin G - chemistry | Interleukin-4 - metabolism | Autoimmune Diseases - immunology | Crystallization | Receptors, Cell Surface - metabolism | Inflammation - immunology | Macrophages - cytology | Receptors, IgG - immunology | Cell Adhesion Molecules - metabolism | Immunoglobulins, Intravenous - pharmacology | Receptors, Cell Surface - immunology | Interleukin-4 - immunology | Animals | Arthritis - drug therapy | Ligands | Dendritic Cells - cytology | Immunoglobulins, Intravenous - chemistry | Mice | Basophils - metabolism | Immunoglobulins, Intravenous - immunology | Immunoglobulin G - metabolism | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 443 - 456
The mechanisms underlying human natural killer (NK) cell phenotypic and functional heterogeneity are unknown. Here, we describe the emergence of diverse... 
NATURAL-KILLER-CELLS | ACTIVATION | CMV REACTIVATION | INNATE | RECEPTOR | FCR-GAMMA | DIFFERENTIATION | IMMUNOLOGY | PLZF CONTROLS | EXPRESSION | T-CELLS | Cell Proliferation | Humans | Transcription Factors - deficiency | NK Cell Lectin-Like Receptor Subfamily C - genetics | Receptors, IgG - deficiency | Intracellular Signaling Peptides and Proteins - immunology | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Killer Cells, Natural - pathology | Cytomegalovirus Infections - genetics | Protein-Tyrosine Kinases - deficiency | Protein-Tyrosine Kinases - immunology | T-Lymphocytes, Cytotoxic - pathology | Intracellular Signaling Peptides and Proteins - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | DNA Methylation | Protein-Tyrosine Kinases - genetics | Receptors, IgG - genetics | Microarray Analysis | Antibodies - immunology | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Kruppel-Like Transcription Factors - deficiency | Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Promoter Regions, Genetic | GPI-Linked Proteins - immunology | Signal Transduction | Killer Cells, Natural - virology | T-Lymphocytes, Cytotoxic - virology | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Immunophenotyping | Receptors, IgG - immunology | Transcription Factors - genetics | Killer Cells, Natural - classification | Promyelocytic Leukemia Zinc Finger Protein | Cytomegalovirus - immunology | Epigenesis, Genetic - immunology | Kruppel-Like Transcription Factors - genetics | Kruppel-Like Transcription Factors - immunology | GPI-Linked Proteins - genetics | Virus diseases | Proteins | Epigenetic inheritance | Killer cells | Immunotherapy | Genomics | Medical genetics | Cytomegalovirus infections | T cells | Methylation | Health aspects | Antigens | Flow cytometry | Cytomegalovirus | Data analysis | Biomedical research | Transplants & implants | Cytokines | Leukemia | Cytotoxicity | Infections | Kinases | Diversification | Gene expression | Experiments | Scholarships & fellowships | Lymphocytes | DNA methylation | Epigenetics | Viral infections | Immune system | Cancer | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2908, 2009, Volume 10, Issue 10, pp. 1081 - U58
Journal Article
Mucosal Immunology, ISSN 1933-0219, 03/2016, Volume 9, Issue 2, pp. 352 - 363
In inflammatory bowel diseases, a breakdown in host microbial interactions accompanies sustained activation of immune cells in the gut. Functional studies... 
CD103(+)CD11B(+) DENDRITIC CELLS | TISSUE MACROPHAGES | ANTIGEN-PRESENTING CELLS | LY6C(HI) MONOCYTES | MEDIATED COLITIS | IMMUNOLOGY | DEPENDENT MECHANISM | IMMUNE DEFENSE | T-CELLS | AUTOIMMUNE ENCEPHALOMYELITIS | BOWEL-DISEASE |