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Journal of Clinical Oncology, ISSN 0732-183X, 04/2010, Volume 28, Issue 12, pp. 2085 - 2093
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 06/2017, Volume 73, Issue 6, pp. 689 - 698
Purpose BMS-986142 is an oral, small-molecule reversible inhibitor of Bruton's tyrosine kinase. The main objectives of our phase I studies were to characterize... 
Pharmacodynamics | BMS-986142 | Methotrexate | Pharmacokinetics | Drug–drug interaction | Reversible Bruton’s tyrosine kinase inhibitors | PROTEIN | EFFICACY | ACTIVE RHEUMATOID-ARTHRITIS | Reversible Bruton's tyrosine kinase inhibitors | B-CELL | TYROSINE KINASE INHIBITOR | PHARMACOLOGY & PHARMACY | Drug-drug interaction | LEFLUNOMIDE | Isoquinolines - adverse effects | Isoquinolines - pharmacokinetics | Humans | Methotrexate - pharmacokinetics | Middle Aged | Half-Life | Male | Protein Kinase Inhibitors - adverse effects | Oligopeptides - adverse effects | Antigens, CD - metabolism | Dose-Response Relationship, Drug | Young Adult | Lectins, C-Type - metabolism | Drug Interactions | Adult | Protein Kinase Inhibitors - pharmacokinetics | Double-Blind Method | Drug Administration Schedule | Oligopeptides - pharmacokinetics | Antigens, Differentiation, T-Lymphocyte - metabolism | Protein Kinase Inhibitors - administration & dosage | Adolescent | Methotrexate - administration & dosage | Oligopeptides - administration & dosage | Isoquinolines - administration & dosage | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Safety and security measures | Enzyme inhibitors | Drug interactions | Dosage and administration | Drug therapy, Combination | Radioactive half-life | Pharmacology | Bruton's tyrosine kinase | CD69 antigen | Inhibitors | Drug interaction | Safety | Protein-tyrosine kinase | Drug dosages | Clinical Trial
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 05/2017, Volume 37, Issue 5, pp. 2803 - 2810
Journal Article
Blood, ISSN 0006-4971, 01/2018, Volume 131, Issue 4, pp. 387 - 396
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 16, pp. 3792 - 3800
Immunotoxins based on Pseudomonas exotoxin A (PE) are promising anticancer agents that combine a variable fragment (Fv) from an antibody to a tumor-associated... 
Immunoglobulin Variable Region - adverse effects | Virulence Factors - genetics | Exotoxins - pharmacokinetics | Humans | Antibodies, Monoclonal - adverse effects | Bacterial Toxins - pharmacokinetics | Immunotoxins - adverse effects | Immunotoxins - pharmacology | Endosomes - metabolism | Exotoxins - adverse effects | Lysosomes - metabolism | Virulence Factors - pharmacokinetics | ADP Ribose Transferases - pharmacokinetics | Bacterial Toxins - genetics | Female | Sialic Acid Binding Ig-like Lectin 2 | ADP Ribose Transferases - adverse effects | Antibodies, Monoclonal - pharmacology | Antibodies, Monoclonal - pharmacokinetics | Clinical Trials as Topic | Exotoxins - pharmacology | Bacterial Toxins - adverse effects | Xenograft Model Antitumor Assays | ADP Ribose Transferases - genetics | Antibodies, Monoclonal - genetics | Immunotoxins - genetics | Animals | Bacterial Toxins - pharmacology | Mice, Nude | ADP Ribose Transferases - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Exotoxins - genetics | Immunoglobulin Variable Region - pharmacology | Immunoglobulin Variable Region - genetics | Immunotoxins - pharmacokinetics | Mice | Mice, Inbred BALB C | Virulence Factors - adverse effects | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mutation | Virulence Factors - pharmacology | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2006, Volume 27, Issue 18, pp. 3482 - 3490
Journal Article
Clinical Drug Investigation, ISSN 1173-2563, 11/2016, Volume 36, Issue 11, pp. 889 - 902
SM03 is a novel recombinant, human/mouse chimeric immunoglobulin G1 monoclonal antibody directed against the CD22 antigen on human B lymphocytes. This was the... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | B-LYMPHOCYTE STIMULATOR | TRIAL | BELIMUMAB | EFFICACY | RITUXIMAB |