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Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 06/2015, Volume 13, Issue 6, pp. 1139 - 1150
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 8, pp. 3086 - 3091
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 04/2008, Volume 6, Issue 4, pp. 669 - 676
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2015, Volume 468, Issue 3, pp. 459 - 473
Platelets are activated by a range of stimuli that share little or no resemblance in structure to each other or to recognized ligands, including diesel exhaust... 
Histones | Tyrosine kinase | C-type lectin-like receptor-2 (clec-2) | Syk | Src | Glycoprotein vi (gpvi) | COLLAGEN | THROMBOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | tyrosine kinase | C-type lectin-like receptor-2 (CLEC-2) | DIMERIZATION | PEPTIDE | GAMMA-CHAIN | histones | glycoprotein VI (GPVI) | SIGNALING CASCADE | AGGREGATION | AGONIST | Vehicle Emissions - toxicity | CD36 Antigens - genetics | Membrane Glycoproteins - metabolism | Humans | Molecular Conformation | Coagulants - chemistry | Lectins, C-Type - genetics | CD36 Antigens - chemistry | Lectins, C-Type - chemistry | Lectins, C-Type - metabolism | Peptides - metabolism | CD36 Antigens - metabolism | Lectins, C-Type - agonists | Protein Processing, Post-Translational - drug effects | Coagulants - pharmacology | Coagulants - metabolism | Protein Engineering | Platelet Aggregation Inhibitors - pharmacology | Phosphorylation - drug effects | Platelet Aggregation Inhibitors - metabolism | Coagulants - antagonists & inhibitors | Recombinant Proteins - metabolism | Cell Line | Peptides - chemistry | Jurkat Cells | Membrane Glycoproteins - agonists | Recombinant Proteins - chemistry | Mice, Transgenic | Membrane Glycoproteins - genetics | Peptides - pharmacology | Air Pollutants - metabolism | Animals | Chickens | Platelet Aggregation Inhibitors - chemistry | Hydrophobic and Hydrophilic Interactions | Genes, Reporter - drug effects | Ligands | Platelet Activation - drug effects | Air Pollutants - toxicity | Air Pollutants - chemistry | Crosses, Genetic
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 02/2018, Volume 67, Issue 2, pp. 299 - 308
Insulin has a narrow therapeutic index, reflected in a small margin between a dose that achieves good glycemic control and one that causes hypoglycemia. Once... 
SYSTEM | LECTIN | MANNOSE RECEPTOR | ENDOCRINOLOGY & METABOLISM | HYPOGLYCEMIA | PATCHES | DELIVERY | Mannose-Binding Lectins - metabolism | Recombinant Proteins - therapeutic use | Cricetulus | Humans | Diabetes Mellitus, Type 1 - metabolism | Half-Life | Male | Metabolic Clearance Rate | Recombinant Proteins - pharmacokinetics | Recombinant Proteins - adverse effects | Lectins, C-Type - genetics | Dose-Response Relationship, Drug | Hypoglycemia - prevention & control | Lectins, C-Type - metabolism | Mannose-Binding Lectins - agonists | Hypoglycemic Agents - administration & dosage | Lectins, C-Type - agonists | Receptor, Insulin - genetics | Swine | Drug Design | Swine, Miniature | Drug Evaluation, Preclinical | Hypoglycemia - chemically induced | CHO Cells | Binding, Competitive | Hypoglycemic Agents - therapeutic use | Recombinant Proteins - metabolism | Hyperglycemia - prevention & control | Hypoglycemic Agents - pharmacokinetics | Receptors, Cell Surface - agonists | Insulin, Regular, Human - adverse effects | Receptors, Cell Surface - metabolism | Insulin, Regular, Human - analogs & derivatives | Insulin, Regular, Human - therapeutic use | Insulin, Regular, Human - pharmacokinetics | Diabetes Mellitus, Type 1 - drug therapy | Animals | Mannose-Binding Lectins - genetics | Diabetes Mellitus, Type 1 - blood | Dogs | Animals, Inbred Strains | Ligands | Receptor, Insulin - metabolism | Receptor, Insulin - agonists | Hypoglycemic Agents - adverse effects | Receptors, Cell Surface - genetics | Control | Hypoglycemia | Blood sugar | Insulin | Health aspects | Risk factors
Journal Article