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Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7363, pp. 225 - 228
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2011, Volume 20, Issue 4, pp. 524 - 537
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 20, Issue 3, pp. 315 - 327
Inactivation of the TCA cycle enzyme, fumarate hydratase ( ), drives a metabolic shift to aerobic glycolysis in -deficient kidney tumors and cell lines from... 
CELLS | SUCCINATE-DEHYDROGENASE | COMPLEX-II | ONCOLOGY | GLUCOSE-METABOLISM | GROWTH | HEREDITARY LEIOMYOMATOSIS | RENAL-CANCER | CARCINOMA | HYPOXIA-INDUCIBLE FACTOR-1 | REGULATORY PROTEINS | CELL BIOLOGY | AMP-Activated Protein Kinases - metabolism | Tumor Suppressor Protein p53 - biosynthesis | Cation Transport Proteins - biosynthesis | Humans | Leiomyomatosis - metabolism | Fumarate Hydratase - deficiency | Kidney Neoplasms - metabolism | Glycolysis - drug effects | Iron Regulatory Protein 2 - biosynthesis | Neoplastic Syndromes, Hereditary | Fumarate Hydratase - metabolism | Ribose - biosynthesis | Acetyl Coenzyme A - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Iron - deficiency | Leiomyomatosis - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Leiomyomatosis - congenital | Ribosomal Protein S6 - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | NADP - biosynthesis | Uterine Neoplasms | Animals | Iron Regulatory Protein 1 - metabolism | Thenoyltrifluoroacetone - pharmacology | Ribosomal Protein S6 - metabolism | Kidney Neoplasms - enzymology | Skin Neoplasms | Acetyl-CoA Carboxylase - biosynthesis | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Iron Regulatory Protein 1 - biosynthesis | Acetyl-CoA Carboxylase - metabolism | Iron Regulatory Protein 2 - metabolism | Enzymes | Glucose metabolism | Research | Tumor proteins | Oncology, Experimental | Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 8, Issue 2, pp. 143 - 153
Individuals with hemizygous germline fumarate hydratase (FH) mutations are predisposed to renal cancer. These tumors predominantly exhibit functional... 
HYPOXIA-INDUCIBLE FACTOR | FACTOR 1-ALPHA | NUCLEAR TRANSLOCATOR ARNT | SUCCINATE-DEHYDROGENASE | ONCOLOGY | PROLYL HYDROXYLATION | TUMOR-SUPPRESSOR PROTEIN | HEREDITARY LEIOMYOMATOSIS | CELL-CANCER | HIPPEL-LINDAU PROTEIN | FAMILIAL PHEOCHROMOCYTOMA | CELL BIOLOGY | Up-Regulation | Kidney Neoplasms - genetics | Nuclear Proteins - analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Leiomyomatosis - metabolism | Carcinoma, Renal Cell - genetics | DNA-Binding Proteins - analysis | Male | Kidney Neoplasms - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit | DNA-Binding Proteins - metabolism | Fumarate Hydratase - metabolism | Ketoglutaric Acids - pharmacology | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Adult | Carcinoma, Renal Cell - enzymology | Female | Fumarate Hydratase - antagonists & inhibitors | Nuclear Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors | Hypoxia-Inducible Factor 1 | Nuclear Proteins - metabolism | Fumarate Hydratase - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Syndrome | Transcription Factors - metabolism | Carcinoma, Renal Cell - metabolism | Fumarates - pharmacology | Kidney Neoplasms - enzymology | Alleles | Fumarates - metabolism | Transcription Factors - analysis | Leiomyomatosis - enzymology | Leiomyomatosis - genetics | Medical colleges | Hydroxylation | Pharmacy | Oncology, Experimental | Physiological aspects | Research | Cancer
Journal Article
Reproduction, ISSN 1470-1626, 08/2013, Volume 146, Issue 2, pp. 91 - 102
Journal Article
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 06/2017, Volume 37, Issue 11
Journal Article