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Current Pharmaceutical Design, ISSN 1381-6128, 2013, Volume 19, Issue 14, pp. 2574 - 2593
Journal Article
BioMetals, ISSN 0966-0844, 4/2017, Volume 30, Issue 2, pp. 313 - 320
Gold compounds form a new class of promising metal-based drugs with a number of potential therapeutic applications, particularly in the fields of anticancer... 
Life Sciences | Biochemistry, general | Cysteine proteases | Gold compounds | Microbiology | Enzyme inhibition | Plant Physiology | Parasitic protozoa | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | DRUG-SENSITIVITY | TRYPANOSOMA-BRUCEI-RHODESIENSE | ASSAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | IN-VITRO | LEISHMANIA-MEXICANA | CATHEPSIN-L | ROLES | PARASITE | Cysteine Endopeptidases - chemistry | Plasmodium falciparum - enzymology | Fibroblasts - enzymology | Protozoan Proteins - antagonists & inhibitors | Humans | Cathepsin B - chemistry | Plasmodium falciparum - drug effects | Trypanosoma brucei brucei - enzymology | Trypanosoma cruzi - enzymology | Leishmania infantum - growth & development | Cysteine Proteinase Inhibitors - chemical synthesis | Inhibitory Concentration 50 | Trypanosoma brucei rhodesiense - growth & development | Antiprotozoal Agents - chemical synthesis | Protozoan Proteins - chemistry | Trypanosoma brucei brucei - growth & development | Cell Line | Organogold Compounds - chemical synthesis | Cathepsin B - antagonists & inhibitors | Proteasome Endopeptidase Complex - chemistry | Recombinant Proteins - chemistry | Macrophages - cytology | Cathepsin L - antagonists & inhibitors | Antiprotozoal Agents - pharmacology | Trypanosoma brucei brucei - drug effects | Leishmania infantum - enzymology | Macrophages - enzymology | Animals | Trypanosoma cruzi - growth & development | Organogold Compounds - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Fibroblasts - drug effects | Leishmania infantum - drug effects | Trypanosoma cruzi - drug effects | Macrophages - drug effects | Fibroblasts - cytology | Mice | Trypanosoma brucei rhodesiense - drug effects | Plasmodium falciparum - growth & development | Cathepsin L - chemistry | Trypanosoma brucei rhodesiense - enzymology | Cysteine | Biological products | Protease inhibitors | Proteases | Parasitic diseases | Antiparasitic agents | Technical education | Cystine | Gold | Enzymes | Antimicrobial agents | Cancer therapies | Pharmaceuticals
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2009, Volume 390, Issue 3, pp. 963 - 970
Phosphatidylinositol (PI) kinases are at the heart of one of the major pathways of intracellular signal transduction. Herein, we present the first report on a... 
Trypanosomatids | Inhibitors | Phosphatidylinositol kinases | Phosphatidylinositol-related kinases | SIGNALING PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHAGAS-DISEASE | CELL-GROWTH | ENDOCYTOSIS | BIOPHYSICS | COMPARATIVE GENOMICS | TOR | PHOSPHOINOSITIDE 3-KINASES | AUTOPHAGOSOME FORMATION | ATM | KINASES | Trypanosomatina - growth & development | Humans | Molecular Sequence Data | Trypanocidal Agents - chemistry | Phylogeny | Trypanosoma brucei brucei - enzymology | Autophagy | Trypanosoma cruzi - enzymology | Trypanosomatina - drug effects | Leishmania infantum - growth & development | Enzyme Inhibitors - chemistry | Leishmania major - growth & development | Drug Design | Leishmania braziliensis - enzymology | 1-Phosphatidylinositol 4-Kinase - classification | Trypanosoma brucei brucei - growth & development | Cytokinesis - drug effects | 1-Phosphatidylinositol 4-Kinase - genetics | Amino Acid Sequence | Leishmania braziliensis - drug effects | Leishmania major - drug effects | Enzyme Inhibitors - pharmacology | 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors | Trypanocidal Agents - isolation & purification | Leishmania braziliensis - growth & development | Trypanosoma brucei brucei - drug effects | Enzyme Inhibitors - isolation & purification | Leishmania infantum - enzymology | Trypanosomatina - enzymology | Cell Membrane - enzymology | Androstadienes - chemistry | Lysine - genetics | Leishmania major - enzymology | Trypanosoma cruzi - growth & development | Androstadienes - pharmacology | Trypanocidal Agents - pharmacology | Leishmania infantum - drug effects | Trypanosoma cruzi - drug effects | Phosphatidylinositol | Phosphotransferases
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2016, Volume 109, pp. 173 - 186
Journal Article
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 1, pp. 57 - 66
In its canonical role the reverse transcriptase telomerase recovers the telomeric repeats that are lost during DNA replication. Other locations and activities... 
TRYPANOSOMA-CRUZI TELOMERASE | INFECTIOUS DISEASES | REPLICATION | RNA | KINETOPLAST DNA | REVERSE-TRANSCRIPTASE | SEQUENCE | RESISTANCE | BRUCEI | IMMUNOLOGY | MITOCHONDRIAL-DNA | DAMAGE | Telomerase - analysis | Cytoplasm - enzymology | Mitochondria - enzymology | Leishmania major - enzymology | Oxidative Stress | Cell Nucleus - enzymology | Fungal and Parasitic Infections
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2017, Volume 130, Issue 4, pp. 754 - 766
Journal Article