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PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e115987
Journal Article
Journal Article
Human Gene Therapy, ISSN 1043-0342, 01/2018, Volume 29, Issue 1, pp. 51 - 67
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2013, Volume 9, Issue 10, pp. e1003693 - e1003693
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0172847
Journal Article
Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 9, pp. 1524 - 1533
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2007, Volume 26, Issue 24, pp. 4985 - 4995
The establishment of HIV proviral latency requires the creation of repressive chromatin structures that impair the initiation of transcription and restrict... 
histone deacetylases (HDAC) | histone methylation | HIV transcription | HIV latency | chromatin restriction | Histone deacetylases (HDAC) | Histone methylation | Chromatin restriction | RECRUITMENT | TAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | CELL BIOLOGY | CHROMATIN-REMODELING COMPLEX | POSTINTEGRATION LATENCY | IN-VIVO | GENE-EXPRESSION | TYPE-1 HIV-1 | NF-KAPPA-B | T-CELLS | Chromatin - metabolism | Humans | Recombinant Fusion Proteins - metabolism | RNA - genetics | Lentivirus - metabolism | Lentivirus - genetics | Transcription, Genetic | Nucleic Acid Conformation | Binding Sites | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | Virus Activation | Chromatin - chemistry | RNA - metabolism | HIV-1 - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Promoter Regions, Genetic | Jurkat Cells | HIV Infections - genetics | Gene Silencing | Genetic Vectors - metabolism | HIV Long Terminal Repeat - genetics | Histone Deacetylases - metabolism | HIV-1 - genetics | Genetic Vectors - genetics | Animals | Gene Expression Regulation, Viral | Recombinant Fusion Proteins - genetics | HeLa Cells | HIV Infections - metabolism | Virus Latency - genetics | Signal transduction | Inhibitor drugs | Cellular biology | Ribonucleic acid | Human immunodeficiency virus--HIV | Human immunodeficiency virus | Molecular biology | Ribonucleic acid--RNA | Virology
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2018, Volume 14, Issue 4, p. e1007012
The bromodomain protein Brd4 promotes HIV-1 latency by competitively inhibiting P-TEFb-mediated transcription induced by the virus-encoded Tat protein. Brd4 is... 
ACTIVATION | COMPLEX | ACETYLATION | TAT | MICROBIOLOGY | P-TEFB | HISTONE-ACETYLTRANSFERASE | VIROLOGY | ELONGATION | TIP60 | CURE