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Science Signaling, ISSN 1945-0877, 08/2018, Volume 11, Issue 544, p. eaav1294
Journal Article
Significance, ISSN 1740-9705, 08/2019, Volume 16, Issue 4, pp. 28 - 31
Can Bayesian models reveal the underlying processes that drive the lethality of non‐state terrorism at a local level? Andre Python, Janine B. Illian, Charlotte... 
Terrorism | Bayesian analysis | Lethality
Journal Article
Cell, ISSN 0092-8674, 2011, Volume 146, Issue 1, pp. 67 - 79
Journal Article
BLOOD, ISSN 0006-4971, 06/2007, Volume 109, Issue 11, pp. 4753 - 4760
Vascular development is dependent on various growth factors and certain modifiers critical for providing arterial or venous identity, interaction with the... 
LETHALITY | ANGIOGENESIS | EPHRIN-B2 | NOTCH PATHWAY | HYPOXIA | HEMATOLOGY | EPHB4
Journal Article
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 2019
An exploration of novel control strategies for Leptinotarsa decemlineata is becoming more pressing given rapid evolution of insecticide resistance and rise of... 
Development | Taiman | Lethality | RNA interference | Leptinotarsa decemlineata
Journal Article
Bangladesh Journal of Pharmacology, ISSN 1991-007X, 06/2017, Volume 12, Issue 2, pp. 186 - 189
Brine shrimp lethality assay is an important tool for the preliminary cytotoxicity assay of plant extract and others based on the ability to kill a laboratory... 
Brine shrimp | Lethality assay
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 8, pp. 3406 - 3411
Journal Article
Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6225, pp. 1002 - 1006
  When stem cells progress from an embryonic pluripotent state toward a particular lineage, molecular switches dismantle the transcription factor network that... 
Studies | Modifications | MicroRNAs | Government regulations | Depletion | Ribonucleic acids | Stem cells | Decay | In vivo methods and tests | Mammals | Methylation
Journal Article
Genes and Development, ISSN 0890-9369, 06/2000, Volume 14, Issue 12, pp. 1448 - 1459
Chk1, an evolutionarily conserved protein kinase, has been implicated in cell cycle checkpoint control in lower eukaryotes. By gene disruption, we show that... 
Checkpoint | Atm | Chk1 | DNA damage | Atr | Embryonic lethality | checkpoint | embryonic lethality | Research Paper
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3865 - 3878
The SWI/SNF multisubunit complex modulates chromatin structure through the activity of two mutually exclusive catalytic subunits, SMARCA2 and SMARCA4, which... 
CELL LUNG-CANCER | SYNOVIAL SARCOMA | VULNERABILITIES | GENETIC DEFICIENCY | LEUKEMIA MAINTENANCE | ONCOLOGY | BRG1 | COMPLEXES | MUTATIONS | IDENTIFICATION | LETHALITY-BASED STRATEGY
Journal Article
Journal Article
ISSN 0890-9369, 2016
$\textit{PAXX}$ was identified recently as a novel nonhomologous end-joining DNA repair factor in human cells. To characterize its physiological roles, we... 
development | XLF | PAXX | synthetic lethality | ATM | NHEJ
Journal Article
NATURE, ISSN 0028-0836, 01/2003, Volume 421, Issue 6921, pp. 384 - 388
Excessive inflammation and tumour-necrosis factor (TNF) synthesis cause morbidity and mortality in diverse human diseases including endotoxaemia, sepsis,... 
SHOCK | TUMOR-NECROSIS-FACTOR | CLONING | ENDOTOXIN LETHALITY | BUNGAROTOXIN | MULTIDISCIPLINARY SCIENCES | DEFICIENT | CACHECTIN | CALCIUM | MICE
Journal Article
Nature, ISSN 0028-0836, 05/2008, Volume 453, Issue 7195, pp. 662 - 666
Phosphoinositide 3- kinases ( PI3Ks) signal downstream of multiple cell- surface receptor types. Class IA PI3K isoforms(1) couple to tyrosine kinases and... 
CATALYTIC SUBUNIT | P110-DELTA | P110 DELTA | B-CELL | PHOSPHATIDYLINOSITOL 3-KINASE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC LETHALITY | MICE | GROWTH-FACTOR | PHOSPHOINOSITIDE 3-KINASE | EXPRESSION
Journal Article
CELL STEM CELL, ISSN 1934-5909, 07/2007, Volume 1, Issue 1, pp. 113 - 126
Developmental abnormalities, cancer, and premature aging each have been linked to defects in the DNA damage response (DDR). Mutations in the ATR checkpoint... 
EARLY EMBRYONIC LETHALITY | PROGENITORS | DISRUPTION | STABILITY | SECKEL-SYNDROME | GENOME MAINTENANCE | SENESCENCE | DNA-REPAIR | EXPRESSION | CYCLE | CELL BIOLOGY
Journal Article
Critical Reviews in Biochemistry and Molecular Biology, ISSN 1040-9238, 05/2019, Volume 54, Issue 3, pp. 193 - 207
Proliferation requires that cells accumulate sufficient biomass to grow and divide. Cancer cells within tumors must acquire a variety of nutrients, and tumor... 
nutrient limitation | metabolism | tumor microenvironment | collateral lethality | Cancer | Index Medicus
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 10
Hybrid cells of Nicotiana suaveolens x N. tabacum grow normally at 36 degrees C, but immediately express lethality due to probable autoimmune response when... 
ACTIVATION | UBIQUITIN-PROTEASOME SYSTEM | AGGRESOMES | MECHANISM | GENE | MULTIDISCIPLINARY SCIENCES | TIME-COURSE | AUTOPHAGY | TEMPERATURE-SENSITIVE LETHALITY | STRESS | IMPAIRMENT | Proteins | Sodium | Cell death | Cysteine proteinase | Homeostasis | Proteinase inhibitors | Lethality | Phenylbutyric acid | Apoptosis
Journal Article