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British Journal of Cancer, ISSN 0007-0920, 2017, Volume 117, Issue 12, pp. 1777 - 1786
Background: Although chemotherapy is the cornerstone treatment for patients with metastatic colorectal cancer (mCRC), acquired chemoresistance is common and... 
Nuclear internalisation | Acquired resistance | IGF-1R | Colorectal cancer | BRAF mutation | colorectal cancer | I RECEPTOR | TUMOR-CELLS | COMBINATION | acquired resistance | INSULIN | nuclear internalisation | MUTATION STATUS | ONCOLOGY | POOR-PROGNOSIS | KRAS | INHIBITOR | TRANSCRIPTION FACTOR | EXPRESSION | Leucovorin - administration & dosage | Receptor, IGF Type 1 - metabolism | Molecular Chaperones - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Panitumumab | Drug Resistance, Neoplasm | Male | Protein Inhibitors of Activated STAT - metabolism | Protein Transport - drug effects | Cell Nucleus - metabolism | Colorectal Neoplasms - drug therapy | Protein Inhibitors of Activated STAT - genetics | Camptothecin - administration & dosage | Camptothecin - analogs & derivatives | Cell Survival - drug effects | Bevacizumab - administration & dosage | Antibodies, Monoclonal - pharmacology | HCT116 Cells | Curcumin - pharmacology | Molecular Chaperones - genetics | Pyrimidines - pharmacology | Dasatinib - pharmacology | Signal Transduction - drug effects | Sorafenib | Fluorouracil - pharmacology | Niacinamide - analogs & derivatives | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Molecular Targeted Therapy | Organoplatinum Compounds - pharmacology | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Oxaliplatin | Female | Antineoplastic Agents - pharmacology | Gene Silencing | Fatty Acids, Unsaturated - pharmacology | HT29 Cells | Pyrroles - pharmacology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Cetuximab - administration & dosage | Aged | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Colorectal Neoplasms - pathology | Immunohistochemistry | Medical research | Cell survival | Insulin-like growth factor I | RNA-mediated interference | Colorectal carcinoma | Chemoresistance | Clinical trials | Insulin-like growth factors | Metastasis | Insulin | Patients | Survival | Metastases | Proteins | SUMO protein | Chemotherapy | Cell lines | Monoclonal antibodies | Tumors | Cancer | Translational Therapeutics
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2014, Volume 134, Issue 11, pp. 2717 - 2725
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2016, Volume 22, Issue 6, pp. 624 - 631
Cetuximab is a monoclonal antibody that is effective in the treatment of metastatic colorectal cancer (mCRC). Cetuximab blocks epidermal growth factor receptor... 
MEDICINE, RESEARCH & EXPERIMENTAL | 1ST-LINE TREATMENT | PLUS IRINOTECAN | EFFICACY | BIOCHEMISTRY & MOLECULAR BIOLOGY | METASTATIC COLORECTAL-CANCER | CELL BIOLOGY | CALRETICULIN EXPOSURE | COLON-CANCER | BRAF MUTATION | POOLED ANALYSIS | ENDOPLASMIC-RETICULUM | KRAS | Leucovorin - administration & dosage | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Dendritic Cells - immunology | Humans | Cell Death - immunology | X-Box Binding Protein 1 - drug effects | Endoplasmic Reticulum Stress - immunology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Fluorouracil - administration & dosage | Calreticulin - drug effects | Calreticulin - metabolism | Camptothecin - administration & dosage | Dendritic Cells - drug effects | Indoles - pharmacology | Pyrimidinones - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Camptothecin - analogs & derivatives | Disease Models, Animal | Phagocytosis - drug effects | X-Box Binding Protein 1 - immunology | Endoplasmic Reticulum Stress - drug effects | Antibodies, Monoclonal - pharmacology | HCT116 Cells | Phagocytosis - immunology | Cetuximab - pharmacology | Sulfonamides - pharmacology | Unfolded Protein Response | HT29 Cells | Animals | Colorectal Neoplasms - immunology | Proto-Oncogene Proteins B-raf - genetics | X-Box Binding Protein 1 - metabolism | Cell Line, Tumor | Mice | Pyridones - pharmacology | Physiological aspects | Genetic aspects | Immune response | Research | Drug therapy | Colorectal cancer | Care and treatment | Usage | Chemotherapy | Epidermal growth factor | Cell death | Analysis | Endoplasmic reticulum | Cancer | Monoclonal antibodies | Apoptosis | Immune system
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 11/2014, Volume 74, Issue 5, pp. 1029 - 1032
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2015, Volume 288, Issue 2, pp. 258 - 268
4-Acetylantroquinonol B (4-AAQB), closely related to the better known antroquinonol, is a bioactive isolate of the mycelia of , a Taiwanese mushroom with... 
Cancer progression | Chemotherapy | 4-Acetylantroquinonol B | Cancer stem cells | Antrodia camphorata | Colorectal cancer | HEPATOCELLULAR-CARCINOMA CELLS | APOPTOSIS | OXIDATIVE STRESS | ACTIVATION | PLUS IRINOTECAN | ALDEHYDE DEHYDROGENASE | MYCELIUM | PROLIFERATION | ANTROQUINONOL | GROWTH | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Drug Resistance, Neoplasm | Organoplatinum Compounds - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Neoplastic Stem Cells - metabolism | Time Factors | Colorectal Neoplasms - drug therapy | Neoplastic Stem Cells - pathology | Gene Expression Regulation, Neoplastic - drug effects | Spheroids, Cellular | Colorectal Neoplasms - metabolism | HCT116 Cells | 4-Butyrolactone - pharmacology | Tumor Burden | Cyclohexanones - pharmacology | Mice, SCID | HT29 Cells | Xenograft Model Antitumor Assays | Phenotype | Animals | Signal Transduction - drug effects | Mice, Inbred NOD | Cell Proliferation - drug effects | Fluorouracil - pharmacology | 4-Butyrolactone - analogs & derivatives | Antineoplastic Agents, Phytogenic - pharmacology | Colorectal Neoplasms - pathology | Leucovorin - pharmacology | Development and progression | Genetic aspects | Cellular signal transduction | Tumors | Cancer | Index Medicus | PHENOTYPE | SIGNALS | CELL PROLIFERATION | TUMOR CELLS | IN VIVO | 60 APPLIED LIFE SCIENCES | CHEMOTHERAPY | FLUOROURACILS | MAINTENANCE | TYROSINE | INFLAMMATION | CARCINOMAS | PHOSPHOTRANSFERASES | STEM CELLS | RECEPTORS | MUSHROOMS
Journal Article
Journal Article
Critical Reviews in Oncology and Hematology, ISSN 1040-8428, 2013, Volume 89, Issue 2, pp. 217 - 230
Abstract Metastatic colorectal cancer remains a lethal disease with a poor prognosis in the majority of patients. Multiple drug combinations have been... 
Hematology, Oncology and Palliative Medicine | Irinotecan | Oxaliplatin | 5-Fluorouracil | Drug resistance | Overcome resistance | Cetuximab | Re-challenge | Bevacizumab | 1ST-LINE TREATMENT | BIWEEKLY CETUXIMAB | 3RD-LINE THERAPY | FOLINIC ACID | CETUXIMAB-PLUS-IRINOTECAN | COLON-CANCER | ONCOLOGY | HIGH-DOSE LEUCOVORIN | RANDOMIZED PHASE-III | CONTINUOUS-INFUSION 5-FLUOROURACIL | HEMATOLOGY | FLUOROURACIL-LEUCOVORIN | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Rectum - pathology | Humans | Colon - drug effects | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Organoplatinum Compounds - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Fluorouracil - therapeutic use | Organoplatinum Compounds - administration & dosage | Antibodies, Monoclonal, Humanized - administration & dosage | Fluorouracil - administration & dosage | Rectum - drug effects | Antibodies, Monoclonal, Humanized - pharmacology | Colorectal Neoplasms - drug therapy | Camptothecin - administration & dosage | Antineoplastic Agents - pharmacology | Camptothecin - analogs & derivatives | Antibodies, Monoclonal, Humanized - therapeutic use | Camptothecin - therapeutic use | Colon - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Fluorouracil - pharmacology | Camptothecin - pharmacology | Organoplatinum Compounds - therapeutic use | Care and treatment | Drug therapy | Methods | Colorectal cancer | Cancer
Journal Article
Parasitology Research, ISSN 0932-0113, 5/2008, Volume 102, Issue 6, pp. 1227 - 1234
Journal Article
Investigational New Drugs, ISSN 0167-6997, 6/2012, Volume 30, Issue 3, pp. 1012 - 1027
Journal Article
Journal Article