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Blood, ISSN 1528-0020, 2011, Volume 117, Issue 23, pp. 6287 - 6296
B-cell receptor (BCR) signaling is aberrantly activated in chronic lymphocytic leukemia (CLL... 
B-CELLS | SURVIVAL | APOPTOSIS | ACTIVATION | FLUDARABINE PLUS CYCLOPHOSPHAMIDE | RITUXIMAB | LYMPHOMA | PROLIFERATION | INHIBITOR | HEMATOLOGY | EXPRESSION | T-Lymphocytes - enzymology | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Cell Survival - genetics | Apoptosis - genetics | Male | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Receptors, Antigen, B-Cell - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Cell Survival - drug effects | Drug Screening Assays, Antitumor - methods | Interleukin-6 - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Gene Expression Regulation, Leukemic - drug effects | Pyrimidines - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | B-Cell Activating Factor - metabolism | CD40 Ligand - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Gene Expression Regulation, Enzymologic - genetics | Cell Line, Tumor | Receptors, Antigen, B-Cell - genetics | Mice | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mitogen-Activated Protein Kinase 1 - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Gene Expression Regulation, Leukemic - genetics | Protein-Tyrosine Kinases - genetics | CD40 Ligand - metabolism | MAP Kinase Signaling System - genetics | Female | Interleukin-4 - genetics | Protein-Tyrosine Kinases - biosynthesis | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Neoplasm Proteins - biosynthesis | Interleukin-4 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | MAP Kinase Signaling System - drug effects | NF-kappa B - genetics | B-Cell Activating Factor - genetics | Cell Proliferation - drug effects | Lymphoid Neoplasia
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 05/2018, Volume 42, Issue 7, pp. 843 - 854
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a low-grade B-cell neoplasm and ∼2% to 9... 
PD-L1 | chronic lymphocytic leukemia | diffuse large B-cell lymphoma | small lymphocytic lymphoma, Richter transformation | PD-1 | clonal relatedness | SURGERY | Richter transformation | PDL1 EXPRESSION | small lymphocytic lymphoma | PROLIFERATION CENTERS | PROGRAMMED DEATH-1 | PATHOLOGY | LUNG-CANCER | ADVANCED MELANOMA | MOUSE MODEL | HODGKIN LYMPHOMAS | DEATH LIGAND 1 | LYMPHOPROLIFERATIVE DISORDERS | T-CELLS | Immunohistochemistry | Humans | Programmed Cell Death 1 Receptor - analysis | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Tumor Suppressor Protein p53 - genetics | Genes, Immunoglobulin Heavy Chain | Cell Transformation, Neoplastic - genetics | DNA Mutational Analysis | Lymphoma, Large B-Cell, Diffuse - immunology | B-Lymphocytes - pathology | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Genetic Predisposition to Disease | Lymphoma, Large B-Cell, Diffuse - pathology | Biomarkers, Tumor - analysis | In Situ Hybridization, Fluorescence | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Cell Transformation, Neoplastic - immunology | Phenotype | B-Lymphocytes - immunology | B7-H1 Antigen - analysis | Biomarkers, Tumor - genetics | Mutation | Cell Transformation, Neoplastic - pathology | Lymphoma, Large B-Cell, Diffuse - genetics | Clonal Evolution | Cell receptors | Immune response | Development and progression | Lymphomas | Genetic aspects | Cellular signal transduction | Health aspects
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 526, Issue 7574, pp. 525 - 530
Journal Article
Journal Article
Nature genetics, ISSN 1546-1718, 2016, Volume 48, Issue 3, pp. 253 - 264
Journal Article
Blood, ISSN 1528-0020, 2013, Volume 121, Issue 8, pp. 1403 - 1412
Journal Article
Blood, ISSN 1528-0020, 2014, Volume 124, Issue 4, pp. 546 - 554
Journal Article