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Leukemia, ISSN 0887-6924, 02/2017, Volume 31, Issue 2, pp. 272 - 281
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Prognosis | Isoenzymes | Gene Frequency | Humans | Leukemia, Myeloid, Acute - epidemiology | Isocitrate Dehydrogenase - genetics | Myelodysplastic Syndromes - epidemiology | Biomarkers, Tumor | Myelodysplastic Syndromes - enzymology | Leukemia, Myeloid, Acute - mortality | Leukemia, Myeloid, Acute - enzymology | Animals | DNA Mutational Analysis | Isocitrate Dehydrogenase - metabolism | Myelodysplastic Syndromes - genetics | Mutation | Leukemia, Myeloid, Acute - genetics | Care and treatment | Research | Isocitrate dehydrogenase | Myelodysplastic syndromes | Krebs cycle | Mutation (Biology) | Index Medicus | Review
Journal Article
Cancer cell, ISSN 1535-6108, 01/2017, Volume 31, Issue 1, pp. 127 - 141
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Proliferation | Leukemia, Myeloid, Acute - pathology | Alpha-Ketoglutarate-Dependent Dioxygenase FTO - physiology | Humans | Transcriptome | Leukemia, Myeloid, Acute - etiology | Retinoic Acid Receptor alpha - physiology | Leukemia, Myeloid, Acute - enzymology | Adenosine - analogs & derivatives | Adenosine - metabolism | Leukemia, Myeloid, Acute - drug therapy | Suppressor of Cytokine Signaling Proteins - physiology | Methylation | Apoptosis | Tretinoin - pharmacology
Journal Article
Blood, ISSN 0006-4971, 06/2012, Volume 119, Issue 22, pp. 5133 - 5143
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Niacinamide - analogs & derivatives | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Neoplasm Transplantation | Humans | Middle Aged | Aldehyde Dehydrogenase - biosynthesis | Matrix Metalloproteinase 15 - genetics | Male | Transplantation, Heterologous | Bone Marrow - enzymology | Gene Expression Profiling | Phenylurea Compounds | Antineoplastic Agents - administration & dosage | Benzenesulfonates - administration & dosage | Benzenesulfonates - adverse effects | Retinal Dehydrogenase | Janus Kinase 3 - biosynthesis | fms-Like Tyrosine Kinase 3 - genetics | Leukemia, Myeloid, Acute - enzymology | Pyridines - adverse effects | Time Factors | Antineoplastic Agents - adverse effects | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Aldehyde Dehydrogenase 1 Family | Protein Structure, Tertiary | Pyridines - administration & dosage | Leukemia, Myeloid, Acute - pathology | Aldehyde Dehydrogenase - genetics | Gene Expression Regulation, Leukemic | Mice, SCID | fms-Like Tyrosine Kinase 3 - metabolism | Matrix Metalloproteinase 15 - biosynthesis | Drug Resistance, Neoplasm - genetics | Animals | Bone Marrow - pathology | Sorafenib | Janus Kinase 3 - genetics | Mice, Inbred NOD | Mice | Mutation | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Nature chemical biology, ISSN 1552-4450, 11/2015, Volume 11, Issue 11, pp. 878 - 886
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Neoplastic Stem Cells - drug effects | Allosteric Regulation | Humans | Crystallography, X-Ray | Male | Isocitrate Dehydrogenase - antagonists & inhibitors | Dose-Response Relationship, Drug | Leukemia, Myeloid, Acute - enzymology | Pyrazoles - chemistry | Enzyme Inhibitors - pharmacokinetics | Granulocytes - drug effects | Cytosine - metabolism | Dihydropyridines - pharmacokinetics | Enzyme Inhibitors - chemistry | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Granulocytes - pathology | Pyrazoles - pharmacokinetics | Pyrazoles - pharmacology | Dihydropyridines - chemistry | Leukemia, Myeloid, Acute - pathology | Enzyme Inhibitors - pharmacology | Models, Molecular | Isocitrate Dehydrogenase - genetics | Cytosine - chemistry | Granulocytes - enzymology | Xenograft Model Antitumor Assays | Animals | Cell Differentiation - drug effects | Isocitrate Dehydrogenase - chemistry | Allosteric Site | Cell Line, Tumor | CpG Islands | Dihydropyridines - pharmacology | Protein Binding | Isocitrate Dehydrogenase - metabolism | Mice | Kinetics | Mutation | Primary Cell Culture | DNA Methylation - drug effects | Neoplastic Stem Cells - enzymology | Leukemia, Myeloid, Acute - genetics | Index Medicus
Journal Article
Trends in molecular medicine, ISSN 1471-4914, 2010, Volume 16, Issue 9, pp. 387 - 397
Pathology | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Brain Neoplasms - enzymology | Glioma - enzymology | Humans | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Glioma - genetics | Leukemia, Myeloid, Acute - enzymology | Animals | Isocitrate Dehydrogenase - chemistry | Brain Neoplasms - therapy | Glioma - therapy | Isocitrate Dehydrogenase - metabolism | Mutation | Leukemia, Myeloid, Acute - therapy | Leukemia, Myeloid, Acute - genetics | Enzymes | Gliomas | Genetic aspects | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 22, pp. 3607 - 3615
Life Sciences & Biomedicine | Hematology | Science & Technology | Niacinamide - analogs & derivatives | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Humans | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Tandem Repeat Sequences | Antineoplastic Agents - administration & dosage | fms-Like Tyrosine Kinase 3 - genetics | Leukemia, Myeloid, Acute - enzymology | Benzimidazoles - administration & dosage | Leukemia, Myeloid, Acute - drug therapy | Female | Piperidines - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Benzimidazoles - therapeutic use | Protein Kinase Inhibitors - pharmacokinetics | Cell Survival - drug effects | Piperidines - administration & dosage | Benzimidazoles - pharmacokinetics | Mice, SCID | Niacinamide - administration & dosage | Drug Synergism | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Animals | Phenylurea Compounds - administration & dosage | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Sorafenib | Cell Line, Tumor | Mice, Inbred NOD | Mice | Mutation | Leukemia, Myeloid, Acute - genetics | Index Medicus | Abridged Index Medicus | Myeloid Neoplasia
Journal Article
American journal of hematology, ISSN 0361-8609, 04/2015, Volume 90, Issue 4, pp. 276 - 281
Life Sciences & Biomedicine | Hematology | Science & Technology | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Azacitidine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Staurosporine - analogs & derivatives | Myelodysplastic Syndromes - enzymology | Dose-Response Relationship, Drug | Young Adult | fms-Like Tyrosine Kinase 3 - genetics | Leukemia, Myeloid, Acute - enzymology | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Myelodysplastic Syndromes - drug therapy | Azacitidine - administration & dosage | Drug Administration Schedule | Staurosporine - adverse effects | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Staurosporine - therapeutic use | Myelodysplastic Syndromes - mortality | Aged | Mutation | Azacitidine - therapeutic use | Staurosporine - administration & dosage | Index Medicus | AML | AZA | midostaurin | MDS
Journal Article
European journal of cancer (1990), ISSN 0959-8049, 11/2017, Volume 86, pp. 233 - 239
Acute myeloid leukemia | FLT3-ITD | Sorafenib | Hematopoietic stem cell transplantation | Life Sciences & Biomedicine | Oncology | Science & Technology | Niacinamide - analogs & derivatives | Recurrence | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Tandem Repeat Sequences | Protein Kinase Inhibitors - adverse effects | Transplantation, Homologous | Young Adult | fms-Like Tyrosine Kinase 3 - genetics | Leukemia, Myeloid, Acute - enzymology | Time Factors | Antineoplastic Agents - adverse effects | Phenylurea Compounds - adverse effects | Adult | Female | Retrospective Studies | Leukemia, Myeloid, Acute - therapy | Risk Factors | Kaplan-Meier Estimate | Niacinamide - adverse effects | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Treatment Outcome | Remission Induction | Disease Progression | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Protein Kinase Inhibitors - therapeutic use | Adolescent | Aged | Biomarkers, Tumor - genetics | Germany | Leukemia, Myeloid, Acute - genetics | Stem Cell Transplantation - adverse effects | Antimitotic agents | Tyrosine | Relapse | Care and treatment | Analysis | Patient outcomes | Stem cells | Transplantation | Antineoplastic agents | Hematopoietic stem cells | Diseases | Transplants & implants | Leukemia | Stem cell transplantation | Remission | Flt3 protein | Patients | Protein-tyrosine kinase | Survival | Index Medicus
Journal Article