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Journal of the National Cancer Institute, ISSN 0027-8874, 7/2008, Volume 100, Issue 13, pp. 926 - 939
Background Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations are associated with failure of... 
CHRONIC MYELOGENOUS LEUKEMIA | CYTOGENETIC RESPONSES | IN-VITRO | SIGNALING PATHWAYS | ONCOLOGY | TYROSINE KINASE | BLAST CRISIS | CLINICAL RESISTANCE | DOMAIN MUTATIONS | SRC FAMILY KINASES | CHRONIC MYELOID-LEUKEMIA | Phosphorylation | Immunoprecipitation | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Middle Aged | Immunoblotting | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - drug therapy | Caspases - metabolism | Fusion Proteins, bcr-abl | Antineoplastic Agents - adverse effects | Mass Spectrometry | src-Family Kinases - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Adult | Female | Cell Survival - drug effects | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - enzymology | Piperazines - therapeutic use | Enzyme Activation - drug effects | Imatinib Mesylate | Piperazines - adverse effects | Drug Resistance, Neoplasm - genetics | Animals | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Cell Line, Tumor | Aged | Mice | Benzamides | Protein-Tyrosine Kinases - antagonists & inhibitors | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Gene expression | Risk factors | Oncology | Chemotherapy | Cellular biology | Drug resistance | Kinases | Leukemia | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 01/2007, Volume 109, Issue 1, pp. 61 - 64
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 07/2017, Volume 143, Issue 7, pp. 1225 - 1233
Journal Article
Blood, ISSN 0006-4971, 12/2011, Volume 118, Issue 24, pp. 6392 - 6398
Journal Article
Journal Article
Blood, ISSN 0006-4971, 02/2017, Volume 129, Issue 6, pp. 715 - 722
Chronic neutrophilic leukemia (CNL) is a distinct myeloproliferative neoplasm with a high prevalence (> 80%) of mutations in the colony-stimulating factor 3... 
CHRONIC MYELOGENOUS LEUKEMIA | ATYPICAL CML | STIMULATING-FACTOR-RECEPTOR | CLONAL HEMATOPOIESIS | SEVERE CONGENITAL NEUTROPENIA | MYELOPROLIFERATIVE NEOPLASMS | ACUTE MYELOID-LEUKEMIA | G-CSF RECEPTOR | HEMATOLOGY | SETBP1 MUTATIONS | CHRONIC MYELOMONOCYTIC LEUKEMIA | Genomics | Humans | Antineoplastic Agents - therapeutic use | Serine-Arginine Splicing Factors - metabolism | Serine-Arginine Splicing Factors - genetics | DNA-Binding Proteins - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - drug therapy | Receptors, Colony-Stimulating Factor - genetics | Receptors, Colony-Stimulating Factor - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - pathology | Leukemia, Neutrophilic, Chronic - pathology | Nuclear Proteins - genetics | Neutrophils - metabolism | Repressor Proteins - metabolism | Neutrophils - pathology | Proto-Oncogene Proteins - metabolism | Neutrophils - drug effects | Gene Expression Regulation, Leukemic - drug effects | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Disease Progression | Splicing Factor U2AF - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Leukemia, Neutrophilic, Chronic - drug therapy | Cell Proliferation - drug effects | Leukemia, Neutrophilic, Chronic - metabolism | Leukemia, Neutrophilic, Chronic - genetics | Mutation | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - metabolism | Clonal Evolution | Practice Guidelines as Topic | Splicing Factor U2AF - metabolism | Myeloproliferative Neoplasms | Review Series
Journal Article
Cancer, ISSN 0008-543X, 02/2017, Volume 123, Issue 3, pp. 459 - 467
BACKGROUND The introduction of novel prognostic factors such as minimal residual disease (MRD) and genomic profiling has led to the reevaluation of the role of... 
hypodiploidy | minimal residual disease | cytogenetics | prognosis | acute lymphoblastic leukemia (ALL) | complex | ACUTE LYMPHOCYTIC-LEUKEMIA | REGIMEN | PHASE-2 | CHILDREN | THERAPY | ONCOLOGY | PREDICTORS | OUTCOMES | Neoplasm, Residual - pathology | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - diagnosis | Prognosis | Humans | Middle Aged | Male | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Cytodiagnosis | Aged, 80 and over | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Vincristine - administration & dosage | Adult | Female | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Doxorubicin - administration & dosage | Treatment Outcome | Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis | Remission Induction | Cytarabine - administration & dosage | Neoplasm, Residual - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Disease-Free Survival | Adolescent | Aged | Usage | Research | Doxorubicin | Vincristine | Risk factors | Chemotherapy | Cyclophosphamide | Cytogenetics | Dosage and administration | Acute lymphocytic leukemia | Drug therapy | Cancer | Dexamethasone | Profiling | Acute lymphatic leukemia | Hypodiploidy | Leukemia | Abnormalities | Minimal residual disease | Lymphatic leukemia | Multivariate analysis | Patients | Survival | Philadelphia chromosome | Medical prognosis | Adults | Triploidy | Pretreatment
Journal Article
Molecular Cancer, ISSN 1476-4598, 02/2018, Volume 17, Issue 1, pp. 40 - 12
Journal Article
Journal Article