X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (462) 462
Publication (52) 52
Book Review (13) 13
Book Chapter (3) 3
Book / eBook (1) 1
Conference Proceeding (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (402) 402
index medicus (280) 280
oncology (204) 204
hematology (179) 179
leukemia (161) 161
animals (133) 133
male (101) 101
cancer (100) 100
mutation (98) 98
female (97) 97
chronic myelogenous leukemia (95) 95
chronic myeloid-leukemia (85) 85
chronic myeloid leukemia (76) 76
signal transduction (76) 76
research (73) 73
genetic aspects (71) 71
middle aged (71) 71
acute myeloid-leukemia (68) 68
kinases (67) 67
leukemia, myelogenous, chronic, bcr-abl positive - genetics (64) 64
cell biology (63) 63
aged (62) 62
adult (58) 58
hemic and lymphatic diseases (58) 58
mice (58) 58
acute lymphoblastic-leukemia (57) 57
gene expression (57) 57
proteins (57) 57
leukemia, myelogenous, chronic, bcr-abl positive - pathology (56) 56
review (56) 56
biochemistry & molecular biology (54) 54
apoptosis (53) 53
leukemia, myelogenous, chronic, bcr-abl positive - metabolism (52) 52
antineoplastic agents - therapeutic use (50) 50
bcr-abl (49) 49
pathology (46) 46
tumors (46) 46
care and treatment (45) 45
imatinib mesylate (45) 45
leukemia, myelogenous, chronic, bcr-abl positive - drug therapy (45) 45
protein kinase inhibitors - therapeutic use (45) 45
health aspects (43) 43
chronic myelomonocytic leukemia (42) 42
fusion proteins, bcr-abl - genetics (42) 42
fusion proteins, bcr-abl - metabolism (42) 42
medicine & public health (42) 42
myeloproliferative disorders - genetics (42) 42
stem cells (42) 42
analysis (40) 40
genetics & heredity (40) 40
leukemia, myeloid, chronic, atypical, bcr-abl negative - genetics (40) 40
development and progression (39) 39
cell line, tumor (38) 38
prognosis (36) 36
janus kinase 2 - genetics (35) 35
tyrosine (35) 35
bone marrow (34) 34
imatinib (34) 34
medicine (34) 34
physiological aspects (34) 34
essential thrombocythemia (33) 33
myeloid leukemia (33) 33
diagnosis (32) 32
philadelphia chromosome (32) 32
phosphorylation (32) 32
polycythemia-vera (32) 32
activation (31) 31
pyrimidines - therapeutic use (31) 31
antineoplastic agents - pharmacology (30) 30
cell proliferation (30) 30
in-vitro (30) 30
protein-tyrosine kinases - metabolism (30) 30
article (29) 29
expression (29) 29
aged, 80 and over (28) 28
flow cytometry (28) 28
myeloproliferative disorders (28) 28
benzamides (27) 27
cells (27) 27
cml (27) 27
genes (27) 27
research article (27) 27
translocation, genetic (27) 27
medicine, research & experimental (26) 26
piperazines - therapeutic use (26) 26
colony-stimulating factor (25) 25
janus kinase 2 - metabolism (25) 25
leukemia, myeloid, acute - genetics (25) 25
leukemia, myeloid, chronic, atypical, bcr-abl negative - pathology (25) 25
myeloproliferative disorders - metabolism (25) 25
signal transduction - drug effects (25) 25
biology (24) 24
bone marrow - pathology (24) 24
cytokines (24) 24
multidisciplinary sciences (24) 24
myeloproliferative disorders - pathology (24) 24
tyrosine kinase (24) 24
apoptosis - drug effects (23) 23
immunology (23) 23
pathogenesis (23) 23
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of the National Cancer Institute, ISSN 0027-8874, 7/2008, Volume 100, Issue 13, pp. 926 - 939
Background Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations are associated with failure of... 
CHRONIC MYELOGENOUS LEUKEMIA | CYTOGENETIC RESPONSES | IN-VITRO | SIGNALING PATHWAYS | ONCOLOGY | TYROSINE KINASE | BLAST CRISIS | CLINICAL RESISTANCE | DOMAIN MUTATIONS | SRC FAMILY KINASES | CHRONIC MYELOID-LEUKEMIA | Phosphorylation | Immunoprecipitation | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Middle Aged | Immunoblotting | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - drug therapy | Caspases - metabolism | Fusion Proteins, bcr-abl | Antineoplastic Agents - adverse effects | Mass Spectrometry | src-Family Kinases - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Adult | Female | Cell Survival - drug effects | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - enzymology | Piperazines - therapeutic use | Enzyme Activation - drug effects | Imatinib Mesylate | Piperazines - adverse effects | Drug Resistance, Neoplasm - genetics | Animals | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Cell Line, Tumor | Aged | Mice | Benzamides | Protein-Tyrosine Kinases - antagonists & inhibitors | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Gene expression | Risk factors | Oncology | Chemotherapy | Cellular biology | Drug resistance | Kinases | Leukemia | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 12/2011, Volume 118, Issue 24, pp. 6392 - 6398
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2013, Volume 45, Issue 1, pp. 18 - 24
Journal Article
Blood, ISSN 0006-4971, 02/2017, Volume 129, Issue 6, pp. 715 - 722
Chronic neutrophilic leukemia (CNL) is a distinct myeloproliferative neoplasm with a high prevalence (> 80%) of mutations in the colony-stimulating factor 3... 
CHRONIC MYELOGENOUS LEUKEMIA | ATYPICAL CML | STIMULATING-FACTOR-RECEPTOR | CLONAL HEMATOPOIESIS | SEVERE CONGENITAL NEUTROPENIA | MYELOPROLIFERATIVE NEOPLASMS | ACUTE MYELOID-LEUKEMIA | G-CSF RECEPTOR | HEMATOLOGY | SETBP1 MUTATIONS | CHRONIC MYELOMONOCYTIC LEUKEMIA | Genomics | Humans | Antineoplastic Agents - therapeutic use | Serine-Arginine Splicing Factors - metabolism | Serine-Arginine Splicing Factors - genetics | DNA-Binding Proteins - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - drug therapy | Receptors, Colony-Stimulating Factor - genetics | Receptors, Colony-Stimulating Factor - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - pathology | Leukemia, Neutrophilic, Chronic - pathology | Nuclear Proteins - genetics | Neutrophils - metabolism | Repressor Proteins - metabolism | Neutrophils - pathology | Proto-Oncogene Proteins - metabolism | Neutrophils - drug effects | Gene Expression Regulation, Leukemic - drug effects | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Disease Progression | Splicing Factor U2AF - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Leukemia, Neutrophilic, Chronic - drug therapy | Cell Proliferation - drug effects | Leukemia, Neutrophilic, Chronic - metabolism | Leukemia, Neutrophilic, Chronic - genetics | Mutation | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - metabolism | Clonal Evolution | Practice Guidelines as Topic | Splicing Factor U2AF - metabolism | Myeloproliferative Neoplasms | Review Series
Journal Article
Journal Article
Blood, ISSN 0006-4971, 04/2014, Volume 123, Issue 17, pp. 2645 - 2651
Journal Article
Leukemia, ISSN 0887-6924, 05/2014, Volume 28, Issue 10, pp. 1988 - 1992
Journal Article
Journal Article
International Journal of Hematology, ISSN 0925-5710, 06/2017, Volume 105, Issue 6, pp. 732 - 742
SETBP1 is a SET-binding protein regulating self-renewal potential through HOXA-protein activation. Somatic SETBP1 mutations were identified by whole exome... 
Myelodysplastic/myeloproliferative neoplasms | Self-renewal potential | SETBP1 | Secondary acute myeloid leukemia | Poor prognosis | ATYPICAL CML | CSF3R | CHRONIC NEUTROPHILIC LEUKEMIA | RECURRENT MUTATIONS | ASXL1 | GENE | DISEASE | HEMATOLOGY | SCHINZEL-GIEDION SYNDROME | MYELODYSPLASTIC SYNDROMES | CHRONIC MYELOMONOCYTIC LEUKEMIA | Humans | Leukemia, Myeloid, Acute - metabolism | Leukemia, Myelomonocytic, Chronic - genetics | Proto-Oncogene Proteins c-myb - genetics | Leukemia, Myelomonocytic, Chronic - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - genetics | Nuclear Proteins - genetics | Leukemia, Myeloid, Acute - therapy | Repressor Proteins - metabolism | Chromosome Deletion | Leukemia, Myelomonocytic, Juvenile | Core Binding Factor Alpha 2 Subunit - metabolism | Leukemia, Myelomonocytic, Chronic - mortality | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - mortality | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - therapy | Proto-Oncogene Proteins c-myb - metabolism | Leukemia, Myeloid, Acute - mortality | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Leukemia, Myelomonocytic, Chronic - therapy | Mice | Chromosomes, Human, Pair 7 - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative - metabolism | Leukemia, Myeloid, Acute - genetics | Genetic aspects | Genetic disorders | Gene mutations | Analysis | Leukemia | Protein binding | Proteins | Rodents | Activation | Mutation | Neoplasms | Tumors
Journal Article
Journal Article
Journal Article