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The lancet oncology, ISSN 1470-2045, 2015, Volume 16, Issue 13, pp. 1295 - 1305
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Young Adult | Arsenicals - therapeutic use | Idarubicin - adverse effects | Time Factors | Adult | Female | Leukocyte Count | Idarubicin - therapeutic use | Real-Time Polymerase Chain Reaction | Arsenicals - adverse effects | Oxides - therapeutic use | Kaplan-Meier Estimate | Treatment Outcome | United Kingdom | Oxides - adverse effects | New Zealand | Tretinoin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Adolescent | Intention to Treat Analysis | Leukemia, Promyelocytic, Acute - mortality | Denmark | Quality of Life | Tretinoin - adverse effects | Leukemia, Promyelocytic, Acute - diagnosis | Biomarkers, Tumor - genetics | Leukemia, Promyelocytic, Acute - genetics | Leukemia, Promyelocytic, Acute - drug therapy | Anthracyclines | Product development | Hospitals | Arsenic | Tretinoin | Index Medicus
Journal Article
2007, Current topics in microbiology and immunology, ISBN 9783540345923, Volume 313, vi, 273
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Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation
Nature medicine, ISSN 1078-8956, 12/2008, Volume 14, Issue 12, pp. 1333 - 1342
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Cyclic AMP-Dependent Protein Kinases - metabolism | Oncogene Proteins, Fusion - metabolism | Phosphorylation | Leukemia, Promyelocytic, Acute - pathology | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Serine - genetics | Cell Transformation, Neoplastic - metabolism | Serine - metabolism | Cyclic AMP - pharmacology | Xenograft Model Antitumor Assays | Leukemia, Promyelocytic, Acute - metabolism | Animals | Cell Differentiation - drug effects | Cell Transformation, Neoplastic - genetics | Mice, Nude | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Mice | Leukemia, Promyelocytic, Acute - genetics | Cell Transformation, Neoplastic - pathology | Tretinoin - pharmacology | Research | Health aspects | Oncogenes | Tretinoin | Signal transduction | Oncology | Chemotherapy | Cellular biology | Leukemia | Index Medicus | Serine | Cyclic AMP | Life Sciences | Ethics | Oncogene Proteins, Fusion | Cell Transformation, Neoplastic | Leukemia, Promyelocytic, Acute | Cell Differentiation | Cyclic AMP-Dependent Protein Kinases
Journal Article
Cancer cell, ISSN 1535-6108, 11/2017, Volume 32, Issue 5, pp. 552 - 560
mouse models | targeted therapy | retinoic acid | differentiation | SUMO | RARA | precision medicine | arsenic | PML | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Oncogene Proteins - genetics | Oncogene Proteins, Fusion - metabolism | Tretinoin - administration & dosage | Tumor Suppressor Proteins - metabolism | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Oncogene Proteins - metabolism | Oncogene Proteins - antagonists & inhibitors | Arsenicals - administration & dosage | Leukemia, Promyelocytic, Acute - metabolism | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Tumor Suppressor Proteins - genetics | Oncogene Proteins, Fusion - antagonists & inhibitors | Leukemia, Promyelocytic, Acute - genetics | Leukemia, Promyelocytic, Acute - drug therapy | Medical colleges | Arsenic | Analysis | Tretinoin | Index Medicus
Journal Article
The New England journal of medicine, ISSN 0028-4793, 07/2013, Volume 369, Issue 2, pp. 111 - 121
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | General aspects | Medical sciences | Oxides - therapeutic use | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Induction Chemotherapy | Male | Consolidation Chemotherapy | Thrombocytopenia - chemically induced | Oxides - adverse effects | Young Adult | Disease-Free Survival | Arsenicals - therapeutic use | Tretinoin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tretinoin - adverse effects | Adult | Female | Aged | Maintenance Chemotherapy | Leukemia, Promyelocytic, Acute - genetics | Neutropenia - chemically induced | Arsenicals - adverse effects | Leukemia, Promyelocytic, Acute - drug therapy | Dosage and administration | Drug therapy, Combination | Research | Tretinoin | Arsenic | Toxicity | Leukemia | Arsenic trioxide | Patients | Studies | Promyeloid leukemia | Chemotherapy | Consolidation | Remission | Pharmaceutical industry | Drug therapy | Retinoic acid | Acute promyeloid leukemia | Index Medicus | Abridged Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 08/2015, Volume 75, Issue 16, pp. 3411 - 3424
Life Sciences & Biomedicine | Oncology | Science & Technology | Multigene Family | Oncogene Proteins, Fusion - metabolism | Leukemia, Promyelocytic, Acute - pathology | Apoptosis - drug effects | Humans | Apoptosis - genetics | Immunoblotting | Receptors, Retinoic Acid - genetics | Leukemia, Promyelocytic, Acute - metabolism | Flow Cytometry | U937 Cells | Tumor Suppressor Proteins - genetics | HEK293 Cells | Antineoplastic Agents - pharmacology | Nuclear Proteins - genetics | Tretinoin - pharmacology | Cell Proliferation - genetics | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Gene Expression Regulation, Leukemic - drug effects | Mice, Transgenic | Nuclear Proteins - metabolism | Receptors, Retinoic Acid - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Transcription Factors - metabolism | Animals | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | HL-60 Cells | Cell Proliferation - drug effects | MicroRNAs - genetics | Leukemia, Promyelocytic, Acute - genetics | Retinoic Acid Receptor alpha | Promyelocytic Leukemia Protein | Index Medicus
Journal Article
Archives of pathology & laboratory medicine (1976), ISSN 0003-9985, 10/2015, Volume 139, Issue 10, pp. 1308 - 1313
Pathology | Life Sciences & Biomedicine | Medical Laboratory Technology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Translocation, Genetic | Diagnosis, Differential | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Promyelocytic Leukemia Zinc Finger Protein | Receptors, Retinoic Acid - genetics | STAT5 Transcription Factor - genetics | Oncogene Proteins, Fusion - genetics | Leukemia, Promyelocytic, Acute - diagnosis | Leukemia, Promyelocytic, Acute - genetics | Kruppel-Like Transcription Factors - genetics | Retinoic Acid Receptor alpha | Leukemia, Promyelocytic, Acute - drug therapy | Arsenic | Index Medicus | Abridged Index Medicus
Journal Article
British journal of haematology, ISSN 0007-1048, 03/2015, Volume 168, Issue 6, pp. 904 - 908
t(7; 17) translocation | retinoic acid resistance | variant acute promyelocytic leukaemia | RARA fusion gene | GTF2I | Variant acute promyelocytic leukaemia | T(7; 17) translocation | Retinoic acid resistance | Life Sciences & Biomedicine | Hematology | Science & Technology | Amino Acid Sequence | Translocation, Genetic | Humans | Mutant Chimeric Proteins - genetics | Molecular Sequence Data | Male | Antineoplastic Agents - therapeutic use | Chromosomes, Human, Pair 17 - genetics | Receptors, Retinoic Acid - genetics | Drug Resistance, Neoplasm - genetics | Transcription Factors, TFII - genetics | Tretinoin - therapeutic use | Base Sequence | Fatal Outcome | Adult | Leukemia, Promyelocytic, Acute - genetics | Chromosomes, Human, Pair 7 - genetics | Neoplasm Proteins - genetics | Retinoic Acid Receptor alpha | Karyotype | Tretinoin | Index Medicus
Journal Article
Leukemia, ISSN 0887-6924, 08/2016, Volume 30, Issue 8, pp. 1672 - 1681
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Recurrence | Exome - genetics | Humans | Cell Differentiation | Gene Expression Profiling | Leukemia, Promyelocytic, Acute - genetics | Transcription Factors - genetics | DNA Mutational Analysis - methods | DNA-Binding Proteins - genetics | Nuclear Proteins - genetics | Relapse | Dosage and administration | Research | Gene expression | Risk factors | Tretinoin | Diseases | Index Medicus | Original
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